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Protein
Submitted name:

Upstream stimulatory factor 2

Gene

USF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Upstream stimulatory factor 2Imported
Gene namesi
Name:USF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105698.15
HGNCiHGNC:12594 USF2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105698

PTM / Processingi

Proteomic databases

MaxQBiM0QYU7
PeptideAtlasiM0QYU7
PRIDEiM0QYU7

Expressioni

Gene expression databases

BgeeiENSG00000105698 Expressed in 234 organ(s), highest expression level in frontal cortex
ExpressionAtlasiM0QYU7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliM0QYU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 95BHLHInterPro annotationAdd BLAST56

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili92 – 143Sequence analysisAdd BLAST52

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INSC Eukaryota
ENOG4111DV1 LUCA
GeneTreeiENSGT00390000004498

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

M0QYU7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XSNLILSRCL GKQLCDNTCP LFFSSSCRKI DGTRTPRDER RRAQHNEVER
60 70 80 90 100
RRRDKINNWI VQLSKIIPDC NADNSKTGAS KGGILSKACD YIRELRQTNQ
110 120 130 140
RMQETFKEAE RLQMDNELLR QQIEELKNEN ALLRAQLQQH NLEMVGEGT
Length:149
Mass (Da):17,328
Last modified:April 3, 2013 - v1
Checksum:i7BA99E4B0FE7E11A
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15853USF2_HUMAN
Upstream stimulatory factor 2
USF2 BHLHB12
346Annotation score:
B4DLJ1B4DLJ1_HUMAN
cDNA FLJ60670, highly similar to Up...
USF2
349Annotation score:
M0QXT0M0QXT0_HUMAN
Upstream stimulatory factor 2
USF2
253Annotation score:
M0QY46M0QY46_HUMAN
Upstream stimulatory factor 2
USF2
170Annotation score:
M0R1C6M0R1C6_HUMAN
Upstream stimulatory factor 2
USF2
143Annotation score:
V9GYR5V9GYR5_HUMAN
Upstream stimulatory factor 2
USF2
112Annotation score:
M0QZ39M0QZ39_HUMAN
Upstream stimulatory factor 2
USF2
86Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei149Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AD000684 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000599625; ENSP00000470081; ENSG00000105698
UCSCiuc060xav.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AD000684 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0QYU7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiM0QYU7
PeptideAtlasiM0QYU7
PRIDEiM0QYU7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000599625; ENSP00000470081; ENSG00000105698
UCSCiuc060xav.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000105698.15
HGNCiHGNC:12594 USF2
OpenTargetsiENSG00000105698
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410INSC Eukaryota
ENOG4111DV1 LUCA
GeneTreeiENSGT00390000004498

Miscellaneous databases

ChiTaRSiUSF2 human

Gene expression databases

BgeeiENSG00000105698 Expressed in 234 organ(s), highest expression level in frontal cortex
ExpressionAtlasiM0QYU7 baseline and differential

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QYU7_HUMAN
AccessioniPrimary (citable) accession number: M0QYU7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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