UniProtKB - M0QYM9 (M0QYM9_HUMAN)
Protein
Submitted name:
Fms-related tyrosine kinase 3 ligand
Gene
FLT3LG
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Fms-related tyrosine kinase 3 ligandImported |
Gene namesi | Name:FLT3LGImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:3766, FLT3LG |
VEuPathDBi | HostDB:ENSG00000090554.12 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 168 – 188 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | Sequence analysisAdd BLAST | 26 | |
ChainiPRO_5004004059 | 27 – 217 | Sequence analysisAdd BLAST | 191 |
Proteomic databases
PeptideAtlasi | M0QYM9 |
PRIDEi | M0QYM9 |
Expressioni
Gene expression databases
Bgeei | ENSG00000090554, Expressed in testis and 113 other tissues |
ExpressionAtlasi | M0QYM9, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 195 – 217 | DisorderedSequence analysisAdd BLAST | 23 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00530000064424 |
OMAi | GCLELQC |
OrthoDBi | 1596773at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR009079, 4_helix_cytokine-like_core IPR004213, Flt3_lig |
PANTHERi | PTHR11032, PTHR11032, 1 hit |
Pfami | View protein in Pfam PF02947, Flt3_lig, 1 hit |
SUPFAMi | SSF47266, SSF47266, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
M0QYM9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTVLAPAWSP TTYLLLLLLL SSGLSGTQDC SFQHSPISSD FAVKIRELSD
60 70 80 90 100
YLLQDYPVTV ASNLQDEELC GGLWRLVLAQ RWMERLKTVA GSKMQGLLER
110 120 130 140 150
VNTEIHFVTK CAFQETSEQL VALKPWITRQ NFSRCLELQC QPDSSTLPPP
160 170 180 190 200
WSPRPLEATA PTAPQPPLLL LLLLPVGLLL LAAAWCLHWQ RTRRRTPRPG
210
EQVPPVPSPQ DLLLVEH
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP49771 | FLT3L_HUMAN | Fms-related tyrosine kinase 3 ligan... | FLT3LG | 235 | Annotation score: | ||
M0QXI0 | M0QXI0_HUMAN | Fms-related tyrosine kinase 3 ligan... | FLT3LG | 187 | Annotation score: | ||
M0R2K0 | M0R2K0_HUMAN | Fms-related tyrosine kinase 3 ligan... | FLT3LG | 58 | Annotation score: | ||
M0R3A6 | M0R3A6_HUMAN | Fms-related tyrosine kinase 3 ligan... | FLT3LG | 132 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010619 Genomic DNA No translation available. |
RefSeqi | XP_005258737.3, XM_005258680.4 XP_005258738.3, XM_005258681.4 |
Genome annotation databases
Ensembli | ENST00000596435; ENSP00000469942; ENSG00000090554 |
GeneIDi | 2323 |
UCSCi | uc061bdp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010619 Genomic DNA No translation available. |
RefSeqi | XP_005258737.3, XM_005258680.4 XP_005258738.3, XM_005258681.4 |
3D structure databases
SMRi | M0QYM9 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | M0QYM9 |
PRIDEi | M0QYM9 |
Protocols and materials databases
Antibodypediai | 2271, 411 antibodies |
DNASUi | 2323 |
Genome annotation databases
Ensembli | ENST00000596435; ENSP00000469942; ENSG00000090554 |
GeneIDi | 2323 |
UCSCi | uc061bdp.1, human |
Organism-specific databases
CTDi | 2323 |
HGNCi | HGNC:3766, FLT3LG |
OpenTargetsi | ENSG00000090554 |
VEuPathDBi | HostDB:ENSG00000090554.12 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00530000064424 |
OMAi | GCLELQC |
OrthoDBi | 1596773at2759 |
Miscellaneous databases
BioGRID-ORCSi | 2323, 17 hits in 999 CRISPR screens |
GenomeRNAii | 2323 |
Gene expression databases
Bgeei | ENSG00000090554, Expressed in testis and 113 other tissues |
ExpressionAtlasi | M0QYM9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR009079, 4_helix_cytokine-like_core IPR004213, Flt3_lig |
PANTHERi | PTHR11032, PTHR11032, 1 hit |
Pfami | View protein in Pfam PF02947, Flt3_lig, 1 hit |
SUPFAMi | SSF47266, SSF47266, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | M0QYM9_HUMAN | |
Accessioni | M0QYM9Primary (citable) accession number: M0QYM9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 3, 2013 |
Last sequence update: | April 3, 2013 | |
Last modified: | April 7, 2021 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |