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Protein
Submitted name:

Numb-like protein

Gene

NUMBL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Numb-like proteinImported
Gene namesi
Name:NUMBLImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105245.9
HGNCiHGNC:8061 NUMBL

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105245

PTM / Processingi

Proteomic databases

MaxQBiM0QYC2
PeptideAtlasiM0QYC2
PRIDEiM0QYC2

Expressioni

Gene expression databases

BgeeiENSG00000105245 Expressed in 207 organ(s), highest expression level in mammary gland
ExpressionAtlasiM0QYC2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliM0QYC2
SMRiM0QYC2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 162PIDInterPro annotationAdd BLAST126

Phylogenomic databases

eggNOGiKOG3537 Eukaryota
ENOG410XT15 LUCA
GeneTreeiENSGT00530000062937

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PfamiView protein in Pfam
PF00640 PID, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
PROSITEiView protein in PROSITE
PS01179 PID, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

M0QYC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKLRQSLRR RKPAYVPEAS RPHQWQADED AVRKGTCSFP VRYLGHVEVE
60 70 80 90 100
ESRGMHVCED AVKKLKAMGR KSVKSVLWVS ADGLRVVDDK TKDLLVDQTI
110 120 130 140 150
EKVSFCAPDR NLDKAFSYIC RDGTTRRWIC HCFLALKDSG ERLSHAVGCA
160 170 180 190 200
FAACLERKQR REKECGVTAA FDASRTSFAR EGSFRLSGGG RPAEREAPDK
210 220 230
KKAEAAAAPT VAPGPAQPGH VSPTPATTSP GEKGE
Length:235
Mass (Da):25,839
Last modified:April 3, 2013 - v1
Checksum:i9076F1059B0DD1C7
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y6R0NUMBL_HUMAN
Numb-like protein
NUMBL
609Annotation score:
A0A0C4DGH3A0A0C4DGH3_HUMAN
Numb-like protein
NUMBL
568Annotation score:
M0QXQ4M0QXQ4_HUMAN
Numb-like protein
NUMBL
214Annotation score:
M0QZV7M0QZV7_HUMAN
Numb-like protein
NUMBL
115Annotation score:
M0R0Q4M0R0Q4_HUMAN
Numb-like protein
NUMBL
110Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei235Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010412 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000598773; ENSP00000469736; ENSG00000105245
UCSCiuc060yvj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010412 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0QYC2
SMRiM0QYC2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiM0QYC2
PeptideAtlasiM0QYC2
PRIDEiM0QYC2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000598773; ENSP00000469736; ENSG00000105245
UCSCiuc060yvj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000105245.9
HGNCiHGNC:8061 NUMBL
OpenTargetsiENSG00000105245
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3537 Eukaryota
ENOG410XT15 LUCA
GeneTreeiENSGT00530000062937

Miscellaneous databases

ChiTaRSiNUMBL human

Gene expression databases

BgeeiENSG00000105245 Expressed in 207 organ(s), highest expression level in mammary gland
ExpressionAtlasiM0QYC2 baseline and differential

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PfamiView protein in Pfam
PF00640 PID, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
PROSITEiView protein in PROSITE
PS01179 PID, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QYC2_HUMAN
AccessioniPrimary (citable) accession number: M0QYC2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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