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Protein
Submitted name:

DnaJ homolog subfamily B member 1

Gene

DNAJB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DnaJ homolog subfamily B member 1Imported
Gene namesi
Name:DNAJB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000132002.7
HGNCiHGNC:5270 DNAJB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132002

PTM / Processingi

Proteomic databases

MaxQBiM0QXK0
PeptideAtlasiM0QXK0
PRIDEiM0QXK0

Expressioni

Gene expression databases

BgeeiENSG00000132002 Expressed in 239 organ(s), highest expression level in hypothalamus
ExpressionAtlasiM0QXK0 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliM0QXK0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini97 – 160DnaJ_CInterPro annotationAdd BLAST64

Phylogenomic databases

eggNOGiKOG0714 Eukaryota
COG0484 LUCA
GeneTreeiENSGT00760000118947

Family and domain databases

InterProiView protein in InterPro
IPR002939 DnaJ_C
IPR008971 HSP40/DnaJ_pept-bd
PfamiView protein in Pfam
PF01556 DnaJ_C, 1 hit
SUPFAMiSSF49493 SSF49493, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

M0QXK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLMCLKGSGP SGGSGGGANG TSFSYTFHGD PHAMFAEFFG GRNPFDTFFG
60 70 80 90 100
QRNGEEGMDI DDPFSGFPMG MGGFTNVNFG RSRSAQEPAR KKQDPPVTHD
110 120 130 140 150
LRVSLEEIYS GCTKKMKISH KRLNPDGKSI RNEDKILTIE VKKGWKEGTK
160
ITFPKEGDQT SN
Length:162
Mass (Da):17,735
Last modified:April 3, 2013 - v1
Checksum:iC453D962A98C620B
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P25685DNJB1_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1 DNAJ1, HDJ1, HSPF1
340Annotation score:
M0R080M0R080_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
183Annotation score:
M0QYT3M0QYT3_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
116Annotation score:
M0QZD0M0QZD0_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
107Annotation score:
M0R1D6M0R1D6_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
91Annotation score:
M0R128M0R128_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
79Annotation score:
A0A1B0GX60A0A1B0GX60_HUMAN
DnaJ homolog subfamily B member 1
DNAJB1
80Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei162Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009004 Genomic DNA No translation available.
AC012318 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000595139; ENSP00000469221; ENSG00000132002
UCSCiuc060uoz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009004 Genomic DNA No translation available.
AC012318 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliM0QXK0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiM0QXK0
PeptideAtlasiM0QXK0
PRIDEiM0QXK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000595139; ENSP00000469221; ENSG00000132002
UCSCiuc060uoz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132002.7
HGNCiHGNC:5270 DNAJB1
OpenTargetsiENSG00000132002
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0714 Eukaryota
COG0484 LUCA
GeneTreeiENSGT00760000118947

Miscellaneous databases

ChiTaRSiDNAJB1 human

Gene expression databases

BgeeiENSG00000132002 Expressed in 239 organ(s), highest expression level in hypothalamus
ExpressionAtlasiM0QXK0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002939 DnaJ_C
IPR008971 HSP40/DnaJ_pept-bd
PfamiView protein in Pfam
PF01556 DnaJ_C, 1 hit
SUPFAMiSSF49493 SSF49493, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QXK0_HUMAN
AccessioniPrimary (citable) accession number: M0QXK0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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