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Protein
Submitted name:

NEDD4 family-interacting protein 2

Gene

Ndfip2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
NEDD4 family-interacting protein 2Imported
Gene namesi
Name:Ndfip2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1923523 Ndfip2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei234 – 257HelicalSequence analysisAdd BLAST24
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Transmembranei296 – 317HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiM0QWK1
PRIDEiM0QWK1

Expressioni

Gene expression databases

BgeeiENSMUSG00000053253 Expressed in 302 organ(s), highest expression level in intestine
ExpressionAtlasiM0QWK1 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4812 Eukaryota
ENOG4111M6U LUCA
GeneTreeiENSGT00390000012721
OrthoDBiEOG091G0IMV

Family and domain databases

InterProiView protein in InterPro
IPR019325 NEDD4/Bsd2
PANTHERiPTHR13396 PTHR13396, 1 hit
PfamiView protein in Pfam
PF10176 DUF2370, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

M0QWK1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRRRSQRAC ASAPSMLSSA RGSPELRRRS ASDAELSAGA EGATGSEAAP
60 70 80 90 100
PGDLGGRTRG GGRGSAAAAA TTSTREAEGA ERRGDTPARK PDPEAGRMDH
110 120 130 140 150
HQLGTGRYQV LHNEEDNSES SAVEQPSTSS LAAPTVEAAA SAPALDPDSP
160 170 180 190 200
PPYSSITVEA PTTSDTDVYS EFYPVPPPYS VATSLPTYDE AEKAKAAALA
210 220 230 240 250
AAAADAPQRN QEEDCTPRDD FSDVEQLRVG NDGIFMLAFF MAFIFNWLGF
260 270 280 290 300
CLSFCITNTI AGRYGAICGF GLSLIKWILI VRFSDYFTGY FNGQYWLWWI
310 320 330
FLVLGLLLFF RGFVNYLKVR NMSESMAAAH RTRYFFLL
Length:338
Mass (Da):36,540
Last modified:April 3, 2013 - v1
Checksum:iB1DEEFAE23FF1141
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q91ZP6NFIP2_MOUSE
NEDD4 family-interacting protein 2
Ndfip2 Kiaa1165, N4wbp5A
311Annotation score:
F6RT43F6RT43_MOUSE
NEDD4 family-interacting protein 2
Ndfip2
312Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113125 Genomic DNA No translation available.
AC141878 Genomic DNA No translation available.
RefSeqiNP_001177918.1, NM_001190989.1
NP_083837.2, NM_029561.4
UniGeneiMm.290669
Mm.387487

Genome annotation databases

EnsembliENSMUST00000181969; ENSMUSP00000137875; ENSMUSG00000053253
GeneIDi76273
KEGGimmu:76273
UCSCiuc007uxp.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113125 Genomic DNA No translation available.
AC141878 Genomic DNA No translation available.
RefSeqiNP_001177918.1, NM_001190989.1
NP_083837.2, NM_029561.4
UniGeneiMm.290669
Mm.387487

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiM0QWK1
PRIDEiM0QWK1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000181969; ENSMUSP00000137875; ENSMUSG00000053253
GeneIDi76273
KEGGimmu:76273
UCSCiuc007uxp.2 mouse

Organism-specific databases

CTDi54602
MGIiMGI:1923523 Ndfip2

Phylogenomic databases

eggNOGiKOG4812 Eukaryota
ENOG4111M6U LUCA
GeneTreeiENSGT00390000012721
OrthoDBiEOG091G0IMV

Miscellaneous databases

ChiTaRSiNdfip2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000053253 Expressed in 302 organ(s), highest expression level in intestine
ExpressionAtlasiM0QWK1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR019325 NEDD4/Bsd2
PANTHERiPTHR13396 PTHR13396, 1 hit
PfamiView protein in Pfam
PF10176 DUF2370, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiM0QWK1_MOUSE
AccessioniPrimary (citable) accession number: M0QWK1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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