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Protein

General transcription factor IIH subunit 4

Gene

M91_10387

Organism
Bos mutus (wild yak)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA damage, DNA repairUniRule annotation, Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
General transcription factor IIH subunit 4UniRule annotation
Gene namesi
ORF Names:M91_10387Imported
OrganismiBos mutus (wild yak)Imported
Taxonomic identifieri72004 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TFB2 family.UniRule annotation

Phylogenomic databases

KOiK03144

Family and domain databases

InterProiView protein in InterPro
IPR004598 TFIIH_p52/Tfb2
PANTHERiPTHR13152 PTHR13152, 1 hit
PfamiView protein in Pfam
PF03849 Tfb2, 1 hit
TIGRFAMsiTIGR00625 tfb2, 1 hit

Sequencei

Sequence statusi: Complete.

L8HWF1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESTPSRGGL NRVHLQCRNL QEFLGGLSPG ILDRLYGHPA TCLAVFRELP
60 70 80 90 100
SLAKNWVMRM LFLEQPLPQA AVALWVKKEF SKAQEESTGL LSGLRIWHTQ
110 120 130 140 150
LLPGGLQGLI LNPIFRQNLR IALLGGGKAW SDDTSQLGPD KHARDVLSLD
160 170 180 190 200
KYAEERWEVV LHFMVGSPSA AVSQDLAQLL SQAGLMKSAE PGEPPCITSA
210 220 230 240 250
GFQFLLLDTP AQLWYFMLQY LQTAQSRGMD LVEILSFLFQ LSFSTLGKDY
260 270 280 290 300
SVEGMSDSLL NFLQHLREFG LVFQRKRKSR RYYPTRLAIN LSSGVSGAGG
310 320 330 340 350
TAHQPGFIVV ETNYRLYAYT ESELQIALIA LFSEMLYRFP NMVVAQVTRE
360 370 380 390 400
SVQQAIASGI TAQQIIHFLR TRAHPVMLKQ TPVLPPTITD QIRLWELERD
410 420 430 440 450
RLRFTEGVLY NQFLSQVDFE LLLAHARELG VLVFENSAKR LMVVTPAGHS
460
DVKRFWKRQK HNS
Length:463
Mass (Da):52,242
Last modified:April 3, 2013 - v1
Checksum:i11965A6665D4488A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH882830 Genomic DNA Translation: ELR48176.1
RefSeqiXP_005907024.1, XM_005906962.2

Genome annotation databases

GeneIDi102280062
KEGGibom:102280062

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH882830 Genomic DNA Translation: ELR48176.1
RefSeqiXP_005907024.1, XM_005906962.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi102280062
KEGGibom:102280062

Organism-specific databases

CTDi2968

Phylogenomic databases

KOiK03144

Family and domain databases

InterProiView protein in InterPro
IPR004598 TFIIH_p52/Tfb2
PANTHERiPTHR13152 PTHR13152, 1 hit
PfamiView protein in Pfam
PF03849 Tfb2, 1 hit
TIGRFAMsiTIGR00625 tfb2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiL8HWF1_9CETA
AccessioniPrimary (citable) accession number: L8HWF1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: October 10, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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