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Protein
Submitted name:

Amino acid adenylation domain-containing protein

Gene

SRIM_12553

Organism
Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Amino acid adenylation domain-containing proteinImported
Gene namesi
ORF Names:SRIM_12553Imported
OrganismiStreptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234)Imported
Taxonomic identifieri1265868 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000011074 Componenti: Unassembled WGS sequence

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei939O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei1984O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3054O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotation

Structurei

3D structure databases

ProteinModelPortaliL8ETW6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini904 – 979CarrierInterPro annotationAdd BLAST76
Domaini1949 – 2024CarrierInterPro annotationAdd BLAST76
Domaini3019 – 3094CarrierInterPro annotationAdd BLAST76

Phylogenomic databases

OrthoDBiPOG091H088I

Family and domain databases

Gene3Di1.10.1200.10, 3 hits
3.30.559.10, 6 hits
InterProiView protein in InterPro
IPR010071 AA_adenyl_domain
IPR036736 ACP-like_sf
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR023213 CAT-like_dom_sf
IPR001242 Condensatn
IPR020806 PKS_PP-bd
IPR009081 PP-bd_ACP
IPR006162 Ppantetheine_attach_site
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF00501 AMP-binding, 3 hits
PF13193 AMP-binding_C, 2 hits
PF00668 Condensation, 3 hits
PF00550 PP-binding, 3 hits
SMARTiView protein in SMART
SM00823 PKS_PP, 3 hits
SUPFAMiSSF47336 SSF47336, 3 hits
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR01733 AA-adenyl-dom, 3 hits
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 3 hits
PS50075 CARRIER, 3 hits
PS00012 PHOSPHOPANTETHEINE, 2 hits

Sequencei

Sequence statusi: Complete.

L8ETW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPFPELFARQ VARTPESTAL VFEGESLSYR ELDARANRLA HWLIGRGVGP
60 70 80 90 100
EARVAVVLPR SVDLAVALLA VLKAGGAYVP VDPEYPEARR AFVLADAAPA
110 120 130 140 150
LVLDAETLRR DFSAHPATDP GARLTPAHAA YVIYTSGSTG VPKGVVVSHA
160 170 180 190 200
GLAGLAASQA ERFAVTGQSR VLQFASPSFD ASVAEFCVAW LSGAALVMAP
210 220 230 240 250
AARLLPGAGL AELVAEQRVT HATLPPSVLA ALPPRTTLPE ITSLVVAGES
260 270 280 290 300
CPPDVAGRWS AGRRMVNAYG PTETTVCATV GEPLSGRVVP TLGTPIADVR
310 320 330 340 350
LQVLDASLRP VPAGGTGELY VTGTGLARGY LGRPALTAER FVACPFGPAG
360 370 380 390 400
ARMYRTGDVV RHRADGELEF VGRADDQVKV RGHRIEPGEV EQTLAAHPGV
410 420 430 440 450
GQAVVAARED RPGDVRLIGY VVPADGPAPD ATGDDAHQVG EWQQMHDLVY
460 470 480 490 500
ADEAKPQDDE PPFGEDFSGW NSSYDGTPIP VDEMRDWRAE TVRRILALRP
510 520 530 540 550
RRVLEMGVGS GLLLSKVAPA CEAYWGADFS APAVERLRRQ VAAVPDLAGK
560 570 580 590 600
VELSCRPADD TTGLPTGYFD TIVINSVTQY FPNAAYFLRV LRNAVDLLAP
610 620 630 640 650
GGRVFVGDIR NRRLLRLFRT AVELTRAGTG TGTGALAAVI DQGVRLEKEL
660 670 680 690 700
LVDPDFFAAL PAELPALAGA DLRLKGTRHH NELTRHRYDA VLHKQPARTV
710 720 730 740 750
SFADVPCLAW GKDVTDTGSL EAALRERAGQ RLRLTGVPNP RLAGEAAAEA
760 770 780 790 800
AVTAGLPVSE ARARLGGTDA ATGAEPELIT ELGARLGLWT AVTWSPDGTE
810 820 830 840 850
GQYDVLFAPE TDLASAAPVA LCRPSGDLTG PPAGHTTDPG AALTTAALVT
860 870 880 890 900
DLQRHLRDRL PAYLVPSAIV ALDTLPLTPN GKVDRAALPA PDLSHAGDGT
910 920 930 940 950
GGRAPRTPRE GVLCELYADV LGVPQVGIDD SFFALGGHSL LATRLIGRIR
960 970 980 990 1000
TALDVDLPIT AVFEAPTVAR LAEHIDAAAS GGRPALRPAP RPDALPLSYA
1010 1020 1030 1040 1050
QRRLWFLHRL EGPSATYNVP LALHLSGELD HDALRAAFGD LLARHESLRT
1060 1070 1080 1090 1100
VFHETAAGTP HQVARDLGDL PDLSSVFSVV RTGPDDVRRL LHEATRHAFD
1110 1120 1130 1140 1150
ITTELPLRAT LFHVKPNEHV LLLLLHHIAG DGWSAAPLAR DLAEAYDARR
1160 1170 1180 1190 1200
KGAAPQWSSL PVQYADYTLW QRDLLGDPQD PDSVHSRQLA YWTDQLKGLP
1210 1220 1230 1240 1250
EEIALPYDRP RPRRATYRGD AFGLELPAAL HADLHTLARD TGTSLFMIVQ
1260 1270 1280 1290 1300
AGLAALLTRL GAGTDIPLGS PVAGRTDQAL DDLVGFFVNT LVLRTDTSGN
1310 1320 1330 1340 1350
PTFRELLRRV RDTDLAAWTH QDLPFEQLVE ALNPVRSAGR QPLFQVVAAV
1360 1370 1380 1390 1400
QNAPEGGFGR LGVRTRSELL STGTAKYDLF FSLWERQGPQ GEPRGLDGFV
1410 1420 1430 1440 1450
EYSTDLFDRG TAETLAAQLV RVLETAAATP DVPLAHLDIL TAGERERLRR
1460 1470 1480 1490 1500
DASAAVPAVR HSTLPELFAE QVARTPEVTA LVFEGEALSY RELDARANRL
1510 1520 1530 1540 1550
AHWLIGQGVG PEARVAVVLP RSVELAVALL AVLKAGGAYV PVDPEYPEAR
1560 1570 1580 1590 1600
RAFVLADAAP VLVLDDEAVR QDLSAHPDTA PVTGLRPAHP AYVIHTSGST
1610 1620 1630 1640 1650
GTPKGVVVTH TGLAALAASQ AERFAVTGQS RVLQFASPSF DASVSEMCVT
1660 1670 1680 1690 1700
WLTGAALVMA PGERLLPGAG LEELLAEQRV THATLPPSVL AALPPQATLP
1710 1720 1730 1740 1750
GLASLVVAGE ACPADLVERW SAGRHMVNAY GPTEATVCAT VGEPLSGRVV
1760 1770 1780 1790 1800
PSLGAPIGDV RLFVLDALLR PVPDGAAGEL YLAGSGLARG YLGRSALTAE
1810 1820 1830 1840 1850
RFVACPFGPA GARMYRTGDL VRRRADGGLE FVGRADDQVK VRGHRIEPGE
1860 1870 1880 1890 1900
VEQALTAHPA VRQAAVAARA DRTGDLRLTG YVVPTADAAR QTLAADLRRD
1910 1920 1930 1940 1950
LLGRLPEHLV PSVITVLDAL PLTPNGKVDR KALPAPDPAR TGGDAGGRAP
1960 1970 1980 1990 2000
RSPQEEILCE LYADLLGVTR VGIDDSFFAL GGHSLLATRL VSRIRAVLGV
2010 2020 2030 2040 2050
ELPIAALFEA PTVEALVERL GLSTARTRTA LRPMPRPEVL PLSYAQRRLW
2060 2070 2080 2090 2100
FQYRLEGPSP TYNIPLMLRI AGPVDEQALR AALGDLLARH ESLRTVFRET
2110 2120 2130 2140 2150
GGTPQQVVLD PATEPDAFDI LSVTEDVPDD PAAFRELLKQ GARHRFDLTA
2160 2170 2180 2190 2200
DLPLHVKLFR VGPQETVLLL LLHHIAGDGW SMAPLSRDVA TAYDARRAGR
2210 2220 2230 2240 2250
APRWTPLPVQ YADYTLWQRQ FLGDPEDPDS VYGRQIAYWR EQLRDLPEEI
2260 2270 2280 2290 2300
ALPFDRPRPQ RASFRGDSIT WEIPADLHQR LHALAGETGT SLYMVLQAGL
2310 2320 2330 2340 2350
ATLFTRLGAG TDIPLGSPVA GRTDQALDDH IGFFVNTLVL RTDTSGDPTF
2360 2370 2380 2390 2400
RELLQRVRNT ALTGWAHQDL PFEQLVEALN PVRSAARNSL FQTMLTLDNA
2410 2420 2430 2440 2450
PEGEFTLGGH PAHTEPVHVD ASRFDMSVFL TERRGAHGER PGMDGAIEFS
2460 2470 2480 2490 2500
TDLFDRGTVE ALAARLVALL DAVTTDPDQS LAHLDVLTAD ERALLLGEVN
2510 2520 2530 2540 2550
ATDRPVPRTS LAEAFQARAS AHPDAPAVTA DGTTLTYAEL NARANRLARH
2560 2570 2580 2590 2600
LISEYGVGRE SRVAVLLDRS ADLVVAILAV LKAGGVYVPL DRRYPAARMR
2610 2620 2630 2640 2650
LIAAETEAVL VLTQRDLPAA AYLPGVPAVH VDDCAGTVAD LPATDLAAPT
2660 2670 2680 2690 2700
AHADTVAYVM YTSGSTGTPK GIAVTQGDVV GLAADHCWGE GAPDGARHTV
2710 2720 2730 2740 2750
LGHASIAFDA STFDLWIPLL NGGHLVMAPP GDLTPDDYRS LLTDHHITAV
2760 2770 2780 2790 2800
LLTTALFNLL AEECPGALAG VRQVWTGGEA ASPSAVQKIL GACPDTRVFN
2810 2820 2830 2840 2850
VYGPTEVTMA ATYHALQGPQ RVAGTVPIGR PMDNMRAYVL DSALRPVAPS
2860 2870 2880 2890 2900
VTGELYVGGA GLARGYLNRP GLTAERFLPD PFGAPGTRMY RTGDLVRWTA
2910 2920 2930 2940 2950
DGRLDYVGRA DTQVKMRGFR IEPGEIETVL DAHPTVAQAT VNLREIAPGD
2960 2970 2980 2990 3000
TRLIAHLVPV TKEAFDATAL RRHLRDRLPA YMVPSALVAL DALPLTPNGK
3010 3020 3030 3040 3050
VDRKALPAPD PRSELGGRGP RSPKEEILCA LYADVLRVPR VGIDDSFFVL
3060 3070 3080 3090 3100
GGHSLMATRL ISRIRTALNV ELPIGALFEA PTVAALAQRI DSATAQPRPP
3110 3120 3130 3140 3150
VKPAARPDTP IPLSYAQRRL WFLHRLEGPS PTYNIPLALR FSGTLDPEAL
3160 3170 3180 3190 3200
RAAIGDLVAR HESLRTVFPR RARAAQQIIL PPDSGRDLLT VVELTPDDLA
3210 3220 3230 3240 3250
PALGKAARHP FDITTEHPLK ATLFTTGPTD HVLLLLLHHI AGDGWSMAPL
3260 3270 3280 3290 3300
SRDLAAAYDA RSAGEGPQWT PLPVQYADYT LWQQQFLGDP ADPDSTYSRQ
3310 3320 3330 3340 3350
LAYWRTQLAD LPAEIPLPLD HPRPEATTYQ GDMFPLQIPA DLHQGLHALA
3360 3370 3380 3390 3400
GDTGTSLYMV VQAGLAALLT HLGAGTDIPL GSPIAGRTDQ ALDDLVGFFV
3410 3420 3430 3440 3450
NTLVLRTDTS GDPTFRELLT RVRETDLAAW SHQDLPFEQL VEALNPARST
3460 3470 3480 3490 3500
ARHPLFQTLL TLDNAPERHF TLAGNPARTE PLDLGVSHFD LSFGLTERRS
3510 3520 3530 3540 3550
GEGAPEGLDG FVEFNTDVFE KGTVVGIAEK LVGVLGAAVA GPDVPISELL

P
Length:3,551
Mass (Da):380,351
Last modified:April 3, 2013 - v1
Checksum:i35963932686B582F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ANSJ01000029 Genomic DNA Translation: ELQ82988.1
RefSeqiWP_003981346.1, NZ_ANSJ01000029.1

Genome annotation databases

EnsemblBacteriaiELQ82988; ELQ82988; SRIM_12553
GeneIDi29533618
PATRICifig|1265868.3.peg.2588

Similar proteinsi

Entry informationi

Entry nameiL8ETW6_STRR1
AccessioniPrimary (citable) accession number: L8ETW6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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