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Protein
Submitted name:

V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_a

Gene

KRAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_aImported
Gene namesi
Name:KRASImported
ORF Names:hCG_14731Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000133703.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiL7RSL8

Expressioni

Gene expression databases

BgeeiENSG00000133703
ExpressionAtlasiL7RSL8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiL7RSL8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395 Eukaryota
COG1100 LUCA
KOiK07827
OrthoDBiEOG091G0UAU

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type
PANTHERiPTHR24070 PTHR24070, 1 hit
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51421 RAS, 1 hit

Sequencei

Sequence statusi: Complete.

L7RSL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI
110 120 130 140 150
KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ
160 170 180
RVEDAFYTLV REIRQYRLKK ISKEEKTPGC VKIKKCIIM
Length:189
Mass (Da):21,656
Last modified:April 3, 2013 - v1
Checksum:i973547B2E11C2C81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX512447 Genomic DNA Translation: AGC09594.1
CH471094 Genomic DNA Translation: EAW96514.1
RefSeqiNP_203524.1, NM_033360.3
XP_006719132.1, XM_006719069.3
UniGeneiHs.505033

Genome annotation databases

GeneIDi3845
KEGGihsa:3845

Similar proteinsi

Entry informationi

Entry nameiL7RSL8_HUMAN
AccessioniPrimary (citable) accession number: L7RSL8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2013
Last sequence update: April 3, 2013
Last modified: July 18, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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