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Entry version 56 (13 Nov 2019)
Sequence version 1 (06 Mar 2013)
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Protein
Submitted name:

Dynein, axonemal, heavy chain 7B

Gene

Dnah7b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi2297 – 2308PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dynein, axonemal, heavy chain 7BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dnah7bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2684953 Dnah7b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
L7N1Y0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
L7N1Y0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
L7N1Y0

PRoteomics IDEntifications database

More...
PRIDEi
L7N1Y0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
L7N1Y0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
L7N1Y0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000041144 Expressed in 25 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
L7N1Y0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000068738

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
L7N1Y0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2284 – 2319EF-handInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 79DisorderedSequence analysisAdd BLAST79
Regioni143 – 166DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili566 – 586Sequence analysisAdd BLAST21
Coiled coili766 – 786Sequence analysisAdd BLAST21
Coiled coili2474 – 2494Sequence analysisAdd BLAST21
Coiled coili2875 – 2923Sequence analysisAdd BLAST49
Coiled coili3219 – 3239Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi150 – 166PolyampholyteSequence analysisAdd BLAST17

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3595 Eukaryota
COG5245 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155282

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
L7N1Y0

Identification of Orthologs from Complete Genome Data

More...
OMAi
DKSMYTI

Database of Orthologous Groups

More...
OrthoDBi
2079at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.20.180.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 AAA_9
IPR041658 AAA_lid_11
IPR042219 AAA_lid_11_sf
IPR026983 DHC_fam
IPR041589 DNAH3_AAA_lid_1
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013602 Dynein_heavy_dom-2
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676 PTHR10676, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF17857 AAA_lid_1, 1 hit
PF18198 AAA_lid_11, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

L7N1Y0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQRATLLDL SESSAPNLAD ADDRKWIPPQ RSRPILPGPQ VLAAMSSKKD
60 70 80 90 100
KLSTKGTSKP PARFLPQLPM DKLSSREKDK LPTTVLPQLT STGVKPQWQQ
110 120 130 140 150
IAPSFHLNMK QENPILEPYP VKNEQSFADY MEYFQQKGKQ LYQIDDKRSG
160 170 180 190 200
PSTSRSKVKS PQKERENFRS TLVKLIMQQD GDLESDVIDE SGIPKATTTA
210 220 230 240 250
REKDISRYYY YIRHGLDTDH VAPMEDSWLE HVLQLVPQHL KILNNSIMVL
260 270 280 290 300
SDEIREDYLL SVKKSIVDFV LKDPRKKDDD GKITELPPHR AEMEVLPKPW
310 320 330 340 350
RRSFLSACSY IRDHLNAMNP MMLAVLDLWH STFKKLRLVD IEEFHNRQDS
360 370 380 390 400
LELSEFQNIV IKHMESAKEM LLKTWFPEVQ NIYYKGNKKK QLPTGKSSAK
410 420 430 440 450
LDSFFNCAAT LMTLQLQDLI LVSMQDFTDL IAQPPESTRA FEHPGFIMRL
460 470 480 490 500
ILDKKTIKFA PDFNDYIDIL INVYEIMIKM VSFVPRVETK LYSQWESKSK
510 520 530 540 550
PTTLKPIILN EIIDTHKEKI REVVLRESVA PTEHLKMYDK YQFLITGKAE
560 570 580 590 600
RDIDEFLFQS QNYERLIEEI RKYQKLEEEI QYTSRKAVRL GMFEMHCEEL
610 620 630 640 650
IKSLVKRADV ICGKLIAKMF RDHQEVNTML CDEFEKIAEK ALSMPLNTAE
660 670 680 690 700
LMEMKAHVQK LETTDMLELR QRLVDSKNCL AFLIECVNFS PADIRLNNSV
710 720 730 740 750
FQWYGRMGEI FDEHRKIIKD KTEQYQEALK FRCERFVEEL ESYAKQVEEF
760 770 780 790 800
HTFGDLLDVQ RYLKKAQVLN GKLDAAADKI EQFNAEEEAY GWVPSVYPQR
810 820 830 840 850
KKIQDGLNPY LRLYETAVEF STKHRGWTEG PYHKVNPDQV EADVGNYWRG
860 870 880 890 900
LYKLEKVFHD SPNALAMTKK VQSMVEEFKQ YIPLIQVICN PGLRPRHWEA
910 920 930 940 950
MSTIVGFPLL PSDDSTVFSF IDMNLEPFLD RFEGISEAAS KEYSLEKAMD
960 970 980 990 1000
KMMTEWDSME FVILPYRESG TYILSSVDDI QMLLDDHIIK TQTMRGSPFI
1010 1020 1030 1040 1050
KPYEKQMREW EGKLLLLQEI LDEWLKVQAT WLYLEPIFSS PDIMSQMPEE
1060 1070 1080 1090 1100
GRRFKAVDKT WRDVMKTVVQ DKRVLAVVTI ERMLERLKKS NELLELILKG
1110 1120 1130 1140 1150
LNEYLEKKRL FFPRFFFLSN DELLEILSET KDPTRVQPHL KKCFEGIAKV
1160 1170 1180 1190 1200
EFTETLDITH MKSSEGEVVE LVDTISTAKA RGQVEKWLVE LERTMIKSIH
1210 1220 1230 1240 1250
KVIGDAIAAY TKNSRISWVR DWPGQTVLCV SQTFWTVEVQ TAIPKGHRAL
1260 1270 1280 1290 1300
EGYLAKCNHQ IDDIVTLVRG KLSKQNRVTL GALVVLDVHA RDVLASLVDK
1310 1320 1330 1340 1350
KISDDSDFQW LSQLRYYWQE NNLETKMINA GLRYGYEYLG NSPRLVITPL
1360 1370 1380 1390 1400
TDRCYRTLFG ALHLHLGGAP EGPAGTGKTE TTKDLAKAVA KQCVVFNCSD
1410 1420 1430 1440 1450
GLDYLALGKF FKGLLSCGAW ACFDEFNRID LEVLSVVAQQ ILTIQRGINA
1460 1470 1480 1490 1500
GTELLVFEGT ELKLDPTCAV FITMNPGYAG RSELPDNLKA LFRTVAMMVP
1510 1520 1530 1540 1550
DYAMIAEIVL YSCGFVTARP LSIKIVATYR LCSEQLSSQH HYNYGMRAVK
1560 1570 1580 1590 1600
SVLTAAGNLK LKYPNENEEI LLLRSIIDVN LPKFLSHDLP LFEGITSDLF
1610 1620 1630 1640 1650
PGVKLPKPDY NELLAAIREN CHTMNLQMTD FFSEKILQIY EMMIVRHGFM
1660 1670 1680 1690 1700
IVGEPFGGKT SAYRVLAGAL NDICEKGLME ENKVQITVLN PKSVTMGQLY
1710 1720 1730 1740 1750
GQFDLVSHEW SDGILAVSFR AFAASSTPDR KWLIFDGPVD AVWIENMNTV
1760 1770 1780 1790 1800
LDDNKKLCLM SGEIIQMSPQ MNLIFEPMDL EVASPATVSR CGMIYMEPHM
1810 1820 1830 1840 1850
LGWRPLMVSW INTLPQSVSI IQKEFIEGLF DRMVPLSVEF IRRHTKELSP
1860 1870 1880 1890 1900
TSDTNLVQSL MNLIDCFMDD FADENKQKER NDRESFSLLE GIFMFSLAWS
1910 1920 1930 1940 1950
VGATCTDDDR LKFDKILREL MEGPISDLTR NKFKLLSGTE QTSSKVFIVP
1960 1970 1980 1990 2000
FPEKGTIYEY QFIPEGLGRW DKWIKKLADT PPIPKDVQFI EIIVPTLDTI
2010 2020 2030 2040 2050
RYSALMHLLT THQKPSIFVG PTGTGKSVYI INFLLNQLNK DIYKPLIVNF
2060 2070 2080 2090 2100
SAQTTAAQTQ NIIMSKLDKR RKGVFGPPLG KRMIVFVDDV NMPAREVYGA
2110 2120 2130 2140 2150
QPPIELLRQW LDHWNWYDLK DCSVIKLVDI QIMCAMGPPG GGRNPITPRY
2160 2170 2180 2190 2200
MRHFNIVTIN EFSDKSMFTI FSRILAWHLR TCYKFPDDFL DLTTQIVNGT
2210 2220 2230 2240 2250
MALYKDAMKN LLPTPAKSHY LFNLRDFSRV IQGVCLSRPE TAENKEAIKR
2260 2270 2280 2290 2300
LWVHEVLRVY YDRLVDNADR SWLIHYIQEI LKNYMQEDFH DLFKNLDFNQ
2310 2320 2330 2340 2350
DGTVEEDDLR SLMFCDFHDP KREDFGYREI ANVDALRMIV EGHLDEYNNM
2360 2370 2380 2390 2400
SKKPMNLVLF RFAIEHISRI SRILKQPRSH ALLVGVGGSG RQSVTRLAAH
2410 2420 2430 2440 2450
MADYSLFQVE ISKGYGSHEW HEDLKVILRK CAENDMQGVF LFTDTQIKRE
2460 2470 2480 2490 2500
SFLEDVNNLL NAGEVPNLFA LDEKQEICEK MRQLDRQRDK TRQTDGSPIA
2510 2520 2530 2540 2550
LFNMFIDRCR NQLHVVLAMS PIGDAFRIRL RKFPALVNCC TIDWFQSWPE
2560 2570 2580 2590 2600
DALEAVASRF LEDIEMSEEI QEGCIDMCKR FHTSTINLST SFHNELQRYN
2610 2620 2630 2640 2650
YVTPTSYLEL ISTFKLLLEK KRNEVMKMKR RYEVGLDKLD SASSQVATMQ
2660 2670 2680 2690 2700
SELEALHPQL KVASREVDEM MIIIERESME VAKTEKIVKA DETVANDQAM
2710 2720 2730 2740 2750
AAKAIKDECD ADLAEALPIL ESALAALDTL TAQDITVVKS MKSPPAGVKL
2760 2770 2780 2790 2800
VMEAICILKG IKADKIPDPT GSGKKIEDFW GPAKRLLGDI RFLQSLHEYD
2810 2820 2830 2840 2850
KDNIPPAYMN IIRKSYIPNP DFVPEKIRNA STAAEGLCKW VIAMDSYDKV
2860 2870 2880 2890 2900
AKIVAPKKIK LAAAEGKLRI AMEGLRKKQA ALYEVQDKLA KLQDTLELNK
2910 2920 2930 2940 2950
QKKADLENQV DLCSKKLERA EQLIGGLGGE KTRWSNSALE LGHLYINLTG
2960 2970 2980 2990 3000
DILISSGVVA YLGAFTSNYR QNQTQEWSQS CKERDIPCSD DYSLMGTLGE
3010 3020 3030 3040 3050
AVTIRAWNIA GLPSDSFSID NGIIIMNARR WPLMIDPQGQ ANKWIKNMEK
3060 3070 3080 3090 3100
TNSLQLIKLS DPDYVRTLEN CIQFGTPVLL ENVGEELDPI LEPLLLKQTF
3110 3120 3130 3140 3150
KQGGSTCIRL GDSTIEYAPD FRFYITTKLR NPHYLPETSV KVTLLNFMIT
3160 3170 3180 3190 3200
PEGMQDQLLG IVVARERPDL EEEKQSLIVQ GADNKRQLKE IEDKILEVLS
3210 3220 3230 3240 3250
LSEGNILEDE TAIKILSSSK SLANEISQKQ EVAEETEKKI DNTRMGYRII
3260 3270 3280 3290 3300
AIHSSILFFS IADLANIEPM YQYSLTWFIN LFILSIENSE KSDILSKRLQ
3310 3320 3330 3340 3350
ILRDHFTYSL YVNICRSLFE KDKLLFSFCL TVNLLIHENA INKTEWRFLL
3360 3370 3380 3390 3400
TGGIGLDNPY TNPCTWLPQK SWDEICRLDD LPAFKTIRRE FMRLKDGWKK
3410 3420 3430 3440 3450
VYDSMEPHHE MFPEDWENKA NDFQRMLIIR CLRPDKVIPM LQEFIIKKLG
3460 3470 3480 3490 3500
RPFIEPPPFD LAKAFGDSNC CAPLIFVLSP GADPMNALLK FADDQGYGGS
3510 3520 3530 3540 3550
KLSSLSLGQG QGPIAMKMLE KAVKDGTWVV LQNCHLATSW MPTLEKVCEE
3560 3570 3580 3590 3600
LSAESTHPDF RIWLTSYPSP NFPVSVLQNG VKMTNEAPKG LRANIIRSYL
3610 3620 3630 3640 3650
MDPISDPEFF GSCKKPEEFK KLLYGLCFFH ALVQERRKFG PLGWNIPYEF
3660 3670 3680 3690 3700
NETDLRISVQ QLHMFLDQYE ELPYDALRYM TGECNYGGRV TDDWDRRTLR
3710 3720 3730 3740 3750
SILNKFFCTE LVENPQYKFD SSGIYFVPPS GDHKSYINYT KTLPLIPAPE
3760 3770 3780 3790 3800
VFGMNANADI TKDQSETQLL FDNILLTQSQ SSGSGTKSSD EVVNEVAGDI
3810 3820 3830 3840 3850
LSKLPNNFDV EAAMRRYPTT YTQSMNTVLV QEMGRFNKLL ITIRESCINI
3860 3870 3880 3890 3900
QKAIKGLVVM STELEEVVSS ILNVKIPVMW MGKSYPSLKP LGSYVNDFLE
3910 3920 3930 3940 3950
RLKFLQQWYE VGPPPVFWLS GFFFTQAFLT GAQQNFARKF TIPIDLLGFD
3960 3970 3980 3990 4000
YEVMDDKEYK NAPEDGVYIH GLFLDGASWN RKTKKLAESH PKVLYDTVPV
4010 4020 4030 4040 4050
MWLKPCKKSD IPKRPSYVAP LYKTSERRGT LSTTGHSTNF VIAMILPSDQ
4060
PKEHWIGRGV ALLCQLNS
Length:4,068
Mass (Da):466,690
Last modified:March 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0849F6AA471F8D0F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A571BD48A0A571BD48_MOUSE
Dynein, axonemal, heavy chain 7B
Dnah7b
4,024Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WPC9A0A087WPC9_MOUSE
Dynein, axonemal, heavy chain 7B
Dnah7b
24Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC108850 Genomic DNA No translation available.
AC122879 Genomic DNA No translation available.
AC125310 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
NP_001153858.1, NM_001160386.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000069293; ENSMUSP00000068738; ENSMUSG00000041144

UCSC genome browser

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UCSCi
uc007awx.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108850 Genomic DNA No translation available.
AC122879 Genomic DNA No translation available.
AC125310 Genomic DNA No translation available.
RefSeqiNP_001153858.1, NM_001160386.1

3D structure databases

SMRiL7N1Y0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000068738

PTM databases

iPTMnetiL7N1Y0
PhosphoSitePlusiL7N1Y0

Proteomic databases

EPDiL7N1Y0
MaxQBiL7N1Y0
PaxDbiL7N1Y0
PRIDEiL7N1Y0

Genome annotation databases

EnsembliENSMUST00000069293; ENSMUSP00000068738; ENSMUSG00000041144
UCSCiuc007awx.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
227058
MGIiMGI:2684953 Dnah7b

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00940000155282
InParanoidiL7N1Y0
OMAiDKSMYTI
OrthoDBi2079at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Dnah7b mouse

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000041144 Expressed in 25 organ(s), highest expression level in testis
ExpressionAtlasiL7N1Y0 baseline and differential

Family and domain databases

Gene3Di1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.20.180.20, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 AAA_9
IPR041658 AAA_lid_11
IPR042219 AAA_lid_11_sf
IPR026983 DHC_fam
IPR041589 DNAH3_AAA_lid_1
IPR042228 Dynein_2_C
IPR042222 Dynein_2_N
IPR041466 Dynein_AAA5_ext
IPR041228 Dynein_C
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_D6_P-loop
IPR013602 Dynein_heavy_dom-2
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF17857 AAA_lid_1, 1 hit
PF18198 AAA_lid_11, 1 hit
PF08393 DHC_N2, 1 hit
PF17852 Dynein_AAA_lid, 1 hit
PF18199 Dynein_C, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 5 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiL7N1Y0_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: L7N1Y0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: November 13, 2019
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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