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UniProtKB - L7MZQ4 (L7MZQ4_ANOCA)

Entry version 37 (07 Apr 2021)
Sequence version 2 (26 Jun 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

SFSWAP

Organism
Anolis carolinensis (Green anole) (American chameleon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingARBA annotation
Biological processTranscription, Transcription regulationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SFSWAPImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnolis carolinensis (Green anole) (American chameleon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28377 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Iguania › Dactyloidae › Anolis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001646 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSACAG00000007220, Expressed in forelimb bud and 14 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		28377.ENSACAP00000007135

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini150 – 192SURP motifInterPro annotationAdd BLAST43
Domaini400 – 440SURP motifInterPro annotationAdd BLAST41

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni205 – 236DisorderedSequence analysisAdd BLAST32
Regioni352 – 389DisorderedSequence analysisAdd BLAST38
Regioni458 – 505DisorderedSequence analysisAdd BLAST48
Regioni537 – 625DisorderedSequence analysisAdd BLAST89
Regioni677 – 855DisorderedSequence analysisAdd BLAST179

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili56 – 80Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi205 – 222PolyampholyteSequence analysisAdd BLAST18
Compositional biasi363 – 386PolarSequence analysisAdd BLAST24
Compositional biasi460 – 501PolarSequence analysisAdd BLAST42
Compositional biasi556 – 579PolarSequence analysisAdd BLAST24
Compositional biasi580 – 625PolyampholyteSequence analysisAdd BLAST46
Compositional biasi682 – 697PolyampholyteSequence analysisAdd BLAST16
Compositional biasi698 – 713BasicSequence analysisAdd BLAST16
Compositional biasi722 – 758BasicSequence analysisAdd BLAST37
Compositional biasi771 – 785PolarSequence analysisAdd BLAST15
Compositional biasi788 – 807BasicSequence analysisAdd BLAST20
Compositional biasi808 – 843PolarSequence analysisAdd BLAST36

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1847, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153892

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_015459_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		L7MZQ4

Identification of Orthologs from Complete Genome Data

More...OMAi		LRAEPCQ

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.790, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000061, Surp
IPR040397, SWAP
IPR035967, SWAP/Surp_sf
IPR019147, SWAP_N_domain

The PANTHER Classification System

More...PANTHERi		PTHR13161, PTHR13161, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09750, DRY_EERY, 1 hit
PF01805, Surp, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01141, DRY_EERY, 1 hit
SM00648, SWAP, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109905, SSF109905, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50128, SURP, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

L7MZQ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDASIMIDR YDGRGHLHDL SEYDAEYSTW NRDYQLSEEE ARIEALCDEE 
        60         70         80         90        100
RYLALRTDLL EEEARQEEEY KRLSEALAED DTYNAVGFTY SSDYYDPSEP 
       110        120        130        140        150
TEEEEQPSRG KVSAMKIENL EENEEPFIAP LGLNVPSDVE LPPTAKMHAI 
       160        170        180        190        200
IERTANFVCK QGAQFEIMLK AKQARNSQFD FLRFDHYLNP YYKFIQKAIK 
       210        220        230        240        250
EGRYATSAQK KKDEKRNINE DADKDDADED DGDNYLHPSL FASKKHNRLE 
       260        270        280        290        300
ELMKPLKVVD PDHPLAVLVR KTQAENNLAA SQSAEGATVP SSQIEYSSDS 
       310        320        330        340        350
TMAAMYYSYY MLPDGSYCLA PPPPGIDMAT YYSALPAGVT VSSTTGVATI 
       360        370        380        390        400
TAPPPPGTIP PQSSEAADES RGGISATTSS TSTIPPVVAI IPPPPDIQPV 
       410        420        430        440        450
IDKLAEYVAR NGIKFETSVR SKNDPRFEFL QPWHQYNAYY EFKKQFFLQK 
       460        470        480        490        500
EDNDSSKHVA SLSEDIPVST ASDVPGETPF STDQTSEDLE SVSQGSNKKD 
       510        520        530        540        550
PNIIKVGNDG KLVKASFAPI SFAIRVKEND LLPLEKNRVK LDDDSDEEGE 
       560        570        580        590        600
EGKEGQENAS STSNSGVAFA SSSNAPEERK PQLTQEELEA KQAKQKLEDR 
       610        620        630        640        650
LAAAAREKLA QASKESKEKQ LQAERKRKAA LFLQNLKNPL ADADVEKMEE 
       660        670        680        690        700
NAFNIETISN MPCSLLTGIK TLPALEAKMP ESPLSRSRDL PREEEKEKKK 
       710        720        730        740        750
KKHKKRSRSR SRSPLSKYHS SSKSRSRTHS KAKHSLPTAY RTVRHSRSRS 
       760        770        780        790        800
RSPRRRAHTP ERRREERSVP TAYRVTNSPG MSRRRTRSRS PNERKKRRSH 
       810        820        830        840        850
SHSKSKARSH SPSISPSKQL VYKNSTHSAS VSPVESRGSS QERAGGASLE 
       860        870        880        890
KEGQISSAIV SSVQSKITQD LMAKVRAMLA ASKNIPTSAS
Length:890
Mass (Da):99,403
Last modified:June 26, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF1FC383048072C3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAWZ02026141 Genomic DNA No translation available.
AAWZ02026142 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSACAT00000007290; ENSACAP00000007135; ENSACAG00000007220

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAWZ02026141 Genomic DNA No translation available.
AAWZ02026142 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi28377.ENSACAP00000007135

Genome annotation databases

EnsembliENSACAT00000007290; ENSACAP00000007135; ENSACAG00000007220

Phylogenomic databases

eggNOGiKOG1847, Eukaryota
GeneTreeiENSGT00940000153892
HOGENOMiCLU_015459_0_0_1
InParanoidiL7MZQ4
OMAiLRAEPCQ

Gene expression databases

BgeeiENSACAG00000007220, Expressed in forelimb bud and 14 other tissues

Family and domain databases

Gene3Di1.10.10.790, 2 hits
InterProiView protein in InterPro
IPR000061, Surp
IPR040397, SWAP
IPR035967, SWAP/Surp_sf
IPR019147, SWAP_N_domain
PANTHERiPTHR13161, PTHR13161, 1 hit
PfamiView protein in Pfam
PF09750, DRY_EERY, 1 hit
PF01805, Surp, 2 hits
SMARTiView protein in SMART
SM01141, DRY_EERY, 1 hit
SM00648, SWAP, 2 hits
SUPFAMiSSF109905, SSF109905, 2 hits
PROSITEiView protein in PROSITE
PS50128, SURP, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiL7MZQ4_ANOCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: L7MZQ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: June 26, 2013
Last modified: April 7, 2021
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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