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Protein

Olfactory receptor

Gene

Olfr1053

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • G protein-coupled receptor activity Source: UniProtKB-KW
  • odorant binding Source: GO_Central
  • olfactory receptor activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr1053Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3030887 Olfr1053

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 47HelicalUniRule annotationAdd BLAST23
Transmembranei59 – 78HelicalUniRule annotationAdd BLAST20
Transmembranei98 – 118HelicalUniRule annotationAdd BLAST21
Transmembranei130 – 151HelicalUniRule annotationAdd BLAST22
Transmembranei197 – 225HelicalUniRule annotationAdd BLAST29
Transmembranei237 – 261HelicalUniRule annotationAdd BLAST25
Transmembranei273 – 292HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiL7MU59
PRIDEiL7MU59

PTM databases

iPTMnetiL7MU59
PhosphoSitePlusiL7MU59

Expressioni

Gene expression databases

BgeeiENSMUSG00000075192 Expressed in 1 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097481

Structurei

3D structure databases

ProteinModelPortaliL7MU59
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IK5R Eukaryota
ENOG4111AZY LUCA
GeneTreeiENSGT00910000144048
InParanoidiL7MU59
KOiK04257
OMAiTFQALMF
OrthoDBiEOG091G0AZH
PhylomeDBiL7MU59

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

L7MU59-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGQQNTTSLP GFILMGITQR TELQLPLFGA FFIIYAVTVM GNLGMIILTK
60 70 80 90 100
LDSHLETPMY FFIRHLAFID LGNSTVICPK MLVDFVMNDK TISFCECATQ
110 120 130 140 150
LSFFLMFIIT EFFILSAMAY DRYVAICNPL LYSVIMSQRL CHVLVGIPYL
160 170 180 190 200
YSTVQALLVT SRIFTSTFCG SNIISHFYCD GIFLLPILCS NAEEIQLVII
210 220 230 240 250
SFSALNLISS FLVVLGSYVL ILIAICRMHS AEGRRKAFST CGSHLTVVVV
260 270 280 290 300
FYGTLFFMYL QPKSTDSLEN DKIASVFYTL VIPMLNPLIY SLRNKEVKNA
310
FYRVLKGQFK INT
Length:313
Mass (Da):35,348
Last modified:March 6, 2013 - v1
Checksum:i8D901F649301E817
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935138 Genomic DNA No translation available.
RefSeqiNP_001171328.1, NM_001177857.1
UniGeneiMm.469867

Genome annotation databases

EnsembliENSMUST00000099897; ENSMUSP00000097481; ENSMUSG00000075192
GeneIDi257974
KEGGimmu:257974
UCSCiuc012bys.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935138 Genomic DNA No translation available.
RefSeqiNP_001171328.1, NM_001177857.1
UniGeneiMm.469867

3D structure databases

ProteinModelPortaliL7MU59
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097481

Protein family/group databases

GPCRDBiSearch...

PTM databases

iPTMnetiL7MU59
PhosphoSitePlusiL7MU59

Proteomic databases

PaxDbiL7MU59
PRIDEiL7MU59

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000099897; ENSMUSP00000097481; ENSMUSG00000075192
GeneIDi257974
KEGGimmu:257974
UCSCiuc012bys.1 mouse

Organism-specific databases

CTDi257974
MGIiMGI:3030887 Olfr1053

Phylogenomic databases

eggNOGiENOG410IK5R Eukaryota
ENOG4111AZY LUCA
GeneTreeiENSGT00910000144048
InParanoidiL7MU59
KOiK04257
OMAiTFQALMF
OrthoDBiEOG091G0AZH
PhylomeDBiL7MU59

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000075192 Expressed in 1 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiL7MU59_MOUSE
AccessioniPrimary (citable) accession number: L7MU59
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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