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Entry version 34 (05 Jun 2019)
Sequence version 1 (06 Mar 2013)
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Protein
Submitted name:

Dedicator of cytokinesis protein 11

Gene

PAL_GLEAN10003568

Organism
Pteropus alecto (Black flying fox)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dedicator of cytokinesis protein 11Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PAL_GLEAN10003568Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPteropus alecto (Black flying fox)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9402 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMegachiropteraPteropodidaePteropodinaePteropus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010552 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9402.XP_006904771.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini156 – 263PHInterPro annotationAdd BLAST108
Domaini631 – 809DHR-1InterPro annotationAdd BLAST179
Domaini1600 – 2027DHR-2InterPro annotationAdd BLAST428

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1238 – 1258DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1242 – 1258PolarSequence analysisAdd BLAST17

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DOCK family.PROSITE-ProRule annotation

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
L5L5I5

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08697 C2_Dock-D, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR037809 C2_Dock-D
IPR035892 C2_domain_sf
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
IPR021816 DOCK_C/D_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain

The PANTHER Classification System

More...
PANTHERi
PTHR23317 PTHR23317, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit
PF11878 DUF3398, 1 hit
PF00169 PH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233 PH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

L5L5I5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDGSRPRVF RQLAFSEKNN RLAAKEKTKV VEPLDYENVI TQRKTQIYSD
60 70 80 90 100
PLRDLLMFPM EDISISVISR QRRTVQSTVP EDAEKRAQSL FVKECIKTYS
110 120 130 140 150
TDWHVVNYKY EDFSGDFRML PCKSLRPEKI PSHVFEIDED CEKDEDSSSL
160 170 180 190 200
CSQKGGVIKQ GWLHKANVNS TITVTMKVFK RRYFYLTQLP DGSYILNSYK
210 220 230 240 250
DEKNSKESKG CIYLDACIDV VQCPKMRRHA FELKMLDKYS HYLAAETEQE
260 270 280 290 300
MEEWLITLKK IIQINTDSLV QEKKETVETA QDDETSSQGK AENIMASLER
310 320 330 340 350
SMHPELMKYG RETEQLNKLS RGDGRQNLFS FDSEVQRLDF SGIEPDIKPF
360 370 380 390 400
EEKCNKRFLV NCHDLTFNIL GQVGDNAKGP PTNVEPFFIN LALFDIKNNC
410 420 430 440 450
KISADFHIDL NPPSVREMLW GTSTQLAGDG NAKCSSPESF IHGIAESHLR
460 470 480 490 500
YIKQGIFSVT NPHPEIFLVA RIEKVLQGNI THCAEPYIKN SDPAKTAQKV
510 520 530 540 550
YRTAKQVCSR LGQYRMPFAW AARPIFKDIQ GSLDLDGRFS PLYKQDSSKL
560 570 580 590 600
SNEDILKFLS EYKKPEKTKL QIIPGHLNIT IECVPVDLSN CITSSYVPLK
610 620 630 640 650
PFKKNCQNIT VEVEEFVPEM TKYCYPFTIY KNHLYVYPLQ LKYDSQKTFA
660 670 680 690 700
KARNIAVCVE FRDSDESDAR ALKCIYGKPA GSVFTTNAYV VVSHHNQNPE
710 720 730 740 750
FYDEIKVELP IHLHQKHHLL FTFYHVSCEI NTKGTTKKQD TVEIPVGFAW
760 770 780 790 800
VPLLKDGRII TFEQQLPVSA NLPPGYLNLN DEESRRQSNV DIKWVDGAKP
810 820 830 840 850
LLKIKSHLES TIYTQDLHVH KFFHHCQLIQ SGSKEVPGEL IKYLKCLHAM
860 870 880 890 900
EIQVMIQFLP VILMQLFRVL TNMTHEDDVP INCTMVLLHI VSKCHEEGLD
910 920 930 940 950
NYLRSFIKYS FRPEKPSAPQ AQLIHETLAT TMIAILKQSA DFLAINKLLK
960 970 980 990 1000
YSWFFFEIIA KSMATYLLEE NKIKLPRGQR FPEAYHHVLH SLLLAIIPHV
1010 1020 1030 1040 1050
TIRYAEIPDE SRNVNYSLAS FLKRCLTLMD RGFVFNLIND YVSGFSPKDP
1060 1070 1080 1090 1100
KILAEYKFEF LQTICNHEHY IPLNLPMTFA KPKLQRVQDS NLEYSLSDEY
1110 1120 1130 1140 1150
CKHHFLVGLL LRETSIALQD NYEIRYTAIS VIKNLLIKHA FDTRYQHKNQ
1160 1170 1180 1190 1200
QAKIAQLYLP FIGLLLENIQ RLAGRDTLYS CAAMPHSASR DEFACGFTSP
1210 1220 1230 1240 1250
TIRGSLSTDK DTAYGSFQNG HGIKREDSRG SLIPEGATGF LDQGSTAENT
1260 1270 1280 1290 1300
RQSSTRSSVS QYNRLDQYEI RSLLMCYLYI VKMISEDTLL TYWNKVSPQE
1310 1320 1330 1340 1350
LINILILLEV CLFHFRYMGK RNIARVHDAW LSKHFGVDRK SQTMPALRNR
1360 1370 1380 1390 1400
SGVMQARLQH LSSLESSFTL NHSSTTTEAD IFHQALLEGN TATEVSLTVL
1410 1420 1430 1440 1450
DTISFFTQCF KSQLLNNDGH NPLMKKVFDI HLAFLKNGQS EVSLKHVFAS
1460 1470 1480 1490 1500
LRAFISKFPS AFFKGRVNMC AAFCYEVLKC CTSKISSTRN EASALLYLLM
1510 1520 1530 1540 1550
RNNFEYTKRK TFLRTHLQII IAVSQLIADV ALSGGSRFQE SLFIINNFAN
1560 1570 1580 1590 1600
SDRPMKATAF PTEVKDLTKR IRTVLMATAQ MKEHEKDPEM LIDLQYSLAK
1610 1620 1630 1640 1650
SYASTPELRK TWLDSMAKIH VKNGDFSEAA MCYVHVAALV AEFLHRKKLF
1660 1670 1680 1690 1700
PNGCSAFKKI TPNIDEEGAM KEDAGMMDVH YSEEVLLELL EQCVDGLWKA
1710 1720 1730 1740 1750
ERYEVISEIS KLIIPIYEKR REFEKLTQVY RTLHGAYTKI LEVMHTKKRL
1760 1770 1780 1790 1800
LGTFFRVAFY GQSFFEEEDG KEYIYKEPKL TGLSEISLRL VKLYGEKFGT
1810 1820 1830 1840 1850
ENVKIIQDSD KVNAKELDPK YAHIQVTYVK PYFDDKELTE RKTEFERNHN
1860 1870 1880 1890 1900
INKFVFEAPY TLTGKKQGCI EEQCKRRTVL TTSNSFPYVK KRIPINYEQQ
1910 1920 1930 1940 1950
INLKPIDVAT DEIKDKTAEL QKLCSSADVD MIQLQLKLQG CVSVQVNAGP
1960 1970 1980 1990 2000
LAYARAFLND SQASKYPPKK VSELKDMFRK FIQACSIALE LNERLIKEDQ
2010 2020 2030 2040 2050
IEYHEGLKSN FREMVKELSD IIHEQASIRI LQEDTMHSPW MSNTLHVFCA
2060
ISGTSSDRGY GSPRYAAEI
Length:2,069
Mass (Da):237,803
Last modified:March 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i540A01F0EB97191A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KB030280 Genomic DNA Translation: ELK18877.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB030280 Genomic DNA Translation: ELK18877.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9402.XP_006904771.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiL5L5I5

Family and domain databases

CDDicd08697 C2_Dock-D, 1 hit
Gene3Di2.30.29.30, 1 hit
2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR037809 C2_Dock-D
IPR035892 C2_domain_sf
IPR027007 DHR-1_domain
IPR027357 DHR-2
IPR026791 DOCK
IPR010703 DOCK_C
IPR021816 DOCK_C/D_N
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR23317 PTHR23317, 1 hit
PfamiView protein in Pfam
PF06920 DHR-2, 1 hit
PF14429 DOCK-C2, 1 hit
PF11878 DUF3398, 1 hit
PF00169 PH, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51650 DHR_1, 1 hit
PS51651 DHR_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiL5L5I5_PTEAL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: L5L5I5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: June 5, 2019
This is version 34 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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