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Protein

Inhibin alpha chain

Gene

PAL_GLEAN10014381

Organism
Pteropus alecto (Black flying fox)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation, HormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibin alpha chainUniRule annotation
Gene namesi
ORF Names:PAL_GLEAN10014381Imported
OrganismiPteropus alecto (Black flying fox)Imported
Taxonomic identifieri9402 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMegachiropteraPteropodidaePteropodinaePteropus
Proteomesi
  • UP000010552 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500396974721 – 367Inhibin alpha chainSequence analysisAdd BLAST347

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 367TGF_BETA_2InterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

InParanoidiL5L0K0
KOiK05500

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR017175 Inhibin_asu
IPR001839 TGF-b_C
IPR015615 TGF-beta-rel
IPR017948 TGFb_CS
PANTHERiPTHR11848 PTHR11848, 1 hit
PTHR11848:SF117 PTHR11848:SF117, 1 hit
PfamiView protein in Pfam
PF00019 TGF_beta, 1 hit
PIRSFiPIRSF037328 Inhibin_alpha_subunit, 1 hit
SMARTiView protein in SMART
SM00204 TGFB, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS00250 TGF_BETA_1, 1 hit
PS51362 TGF_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

L5L0K0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPQLPLLLL LLVVPQRVHS CHGPEVDREL VLAKVRALFL DALGPPAVTG
60 70 80 90 100
EGGNPGVRRL LRRHAVGGFM RRGSEPVEED VSQAILFPAT GASCEDQPAV
110 120 130 140 150
GELAQEAEEG LFTYMFRPSQ HTRSRQVTSA QLWFHTGLDR QATASSNSSG
160 170 180 190 200
PLLGLLALSS KGPTAVPTSL GQAPPCWAVL HMAASALPLL THPVLVLLLR
210 220 230 240 250
CPLCSCSARP ETTPFLVAHT RAKPASRGDR ARRSTPPLPW PWSPAALRLL
260 270 280 290 300
QRPPEEPAAH AHCHRAALNI SFQELGWDQW IVHPPSFVFH YCHGGCGLPT
310 320 330 340 350
QSDLPLPVSG VPPTPVQPFS LVPGAQPCCA ALPGTMRPLR VRTTSDGGYS
360
FKYETVPNLL TQHCACI
Length:367
Mass (Da):39,524
Last modified:March 6, 2013 - v1
Checksum:i46A91C2DDF0344D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB030407 Genomic DNA Translation: ELK17167.1
RefSeqiXP_006906741.1, XM_006906679.2

Genome annotation databases

GeneIDi102896496
KEGGipale:102896496

Similar proteinsi

Entry informationi

Entry nameiL5L0K0_PTEAL
AccessioniPrimary (citable) accession number: L5L0K0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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