Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoglycolate phosphatase

Gene

A13W_02567

Organism
Escherichia coli KTE193
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

2-phosphoglycolate + H2O = glycolate + phosphate.UniRule annotationSAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+UniRule annotationSAAS annotation
  • chlorideUniRule annotation

Pathwayi: glycolate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes glycolate from 2-phosphoglycolate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Phosphoglycolate phosphatase (A13W_02567)
This subpathway is part of the pathway glycolate biosynthesis, which is itself part of Organic acid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycolate from 2-phosphoglycolate, the pathway glycolate biosynthesis and in Organic acid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei13NucleophileUniRule annotation1
Metal bindingi13MagnesiumUniRule annotation1
Metal bindingi15MagnesiumUniRule annotation1
Metal bindingi192MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processCarbohydrate metabolismUniRule annotationSAAS annotation
LigandChlorideUniRule annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00865; UER00834

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycolate phosphataseUniRule annotation (EC:3.1.3.18UniRule annotation)
Short name:
PGPUniRule annotation
Short name:
PGPaseUniRule annotation
Gene namesi
ORF Names:A13W_02567Imported
OrganismiEscherichia coli KTE193Imported
Taxonomic identifieri1181739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000010651 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliL3C397
SMRiL3C397
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.SAAS annotation

Family and domain databases

Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_00495 GPH_hydrolase_bact, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR006346 PGPase/MupP
IPR037512 PGPase_prok
PRINTSiPR00413 HADHALOGNASE
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01549 HAD-SF-IA-v1, 1 hit
TIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01449 PGP_bact, 1 hit

Sequencei

Sequence statusi: Complete.

L3C397-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKFEDIRGV AFDLDGTLVD SAPGLAAAVD MALYALELPV AGEERVITWI
60 70 80 90 100
GNGADVLMER ALTWARQERA TQRKTMGKPP VDDDIPAEEQ VRILRKLFDR
110 120 130 140 150
YYGEVAEEGT FLFPHVADTL GALQAKGLPL GLVTNKPTPF VAPLLEALDI
160 170 180 190 200
AKYFSVVIGG DDVQNKKPHP DPLLLVAERM GIAPQQMLFV GDSRNDIQAA
210 220 230 240 250
KAAGCPSVGL TYGYNYGEAI DLSQPDVIYQ SINDLLPALG LPHSENQESK

ND
Length:252
Mass (Da):27,389
Last modified:March 6, 2013 - v1
Checksum:iFC306F044A1E5521
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ANTH01000026 Genomic DNA Translation: ELC94850.1
RefSeqiWP_001031729.1, NZ_KB732454.1

Genome annotation databases

EnsemblBacteriaiELC94850; ELC94850; A13W_02567
PATRICifig|1181739.3.peg.2641

Similar proteinsi

Entry informationi

Entry nameiL3C397_ECOLX
AccessioniPrimary (citable) accession number: L3C397
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: March 28, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health