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Entry version 30 (26 Feb 2020)
Sequence version 1 (06 Mar 2013)
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Protein
Submitted name:

Type VI secretion protein IcmF

Gene

Psest_4246

Organism
Pseudomonas stutzeri RCH2
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PSTU644801:G1HDU-4187-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion protein IcmFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Psest_4246Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas stutzeri RCH2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri644801 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010820 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei16 – 38HelicalSequence analysisAdd BLAST23
Transmembranei50 – 69HelicalSequence analysisAdd BLAST20
Transmembranei448 – 466HelicalSequence analysisAdd BLAST19

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
644801.Psest_4246

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini200 – 452ImcF-related_NInterPro annotationAdd BLAST253
Domaini502 – 793IcmF-relatedInterPro annotationAdd BLAST292
Domaini927 – 1127IcmF_CInterPro annotationAdd BLAST201

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_003353_2_1_6

KEGG Orthology (KO)

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KOi
K11891

Database of Orthologous Groups

More...
OrthoDBi
393769at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR027417 P-loop_NTPase
IPR017731 T6SS_IcmF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR03348 VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

L0GTK4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTFFGKLGA VLRRTWVWSL LLVLLLAVVV WFVGPLLAVD DYRFWEASTA
60 70 80 90 100
RLLSISVLFL GWGLAMVFTS WRASARRKRD AEDQDVQEQL RRDGLIGEEQ
110 120 130 140 150
QELRHRFKQA LRTLKTSSLY RGRSEKWRSE LPWYLLIGPQ GSGKTSLLDF
160 170 180 190 200
SGLDFPLNRS EQQRLTKDVS GTRYADWYFA DHAVLIDTAG RYLTQPDAAV
210 220 230 240 250
DGSVWDTLLG LLRKRRARPL NGVLVNLPVD QLQGGSELEL ENLARQTRQR
260 270 280 290 300
LHEIHQRLNV DVPVYLVLSK ADRILGFDDF FEQLSREESD QVLGASFRKE
310 320 330 340 350
QNGSDAQVVR QEFEELLRRL NSQVILRMHQ ERDTQRRGRI LDFPHQLGQI
360 370 380 390 400
GERLSLFIEL AFAGNRYQRA SQLRGFYLTS APQLRETLDP LTAGIGRQLG
410 420 430 440 450
LSSSALPTFR SGRARFINQL LSRVIFPEAE LAGLDQREVR RIDWGQRALY
460 470 480 490 500
AGAFGCLLLF GAAWALNFSG NHERLEQLRD IAQRLGSERK TIEAGDEALR
510 520 530 540 550
TLKALDASYA ATQVFPPKDE VSWLRRGGLY QGEAVDPTLH EAYRRDLENL
560 570 580 590 600
LLPRVARQLE AQIRANLNDR EQLLGSLRAY LMLNLAERRE AAFLKDWLAA
610 620 630 640 650
DWSLRHSGNA VAQQGLNTHF ARLLEESFAA YQLNDNLVAK ARAQLRSESL
660 670 680 690 700
AAVVYRMLRD QARNLPDYRL NTQLGPQASL FVGGDYTIPG FYTQRGYQKL
710 720 730 740 750
FVAQGADLVS EILRDNWVLG EGDSLSAKDL GRLLVEMEQL YFRDYAAHWS
760 770 780 790 800
EAIAQLNILP AGSAAQGAAQ LAGLTAANSP LLQLLLEVRE NTRFAGLAEA
810 820 830 840 850
TAGAGELAEA AQGAGGKLGK AAKLATAAAE QAQAALLKNT PDTARKTLER
860 870 880 890 900
RFAPLHQLLD ENGAAGPELS ASLQALDALQ LQLASLAHAS APEQAAFEMA
910 920 930 940 950
KARMGGQRDA INQLRSSAAR LPQPVGKWLG LLAEDSWSLV LTDAYHYLNQ
960 970 980 990 1000
RYRNELYASY RGSLRERYPF SAHSASDVAL ADFREFFKAQ GLADSFFERY
1010 1020 1030 1040 1050
LKPFVSGSAG QYQLRRVDGR GLPLSEHFLA QMSRAQTIRR SFFAENPNEP
1060 1070 1080 1090 1100
QILFKLEPYS LDSSLGRADF RFGNQQLEYR HGPIVQTAFR WPAEADDGRT
1110 1120 1130 1140 1150
SLVVEELGGR RVGIEKNTGP WSLFRLIDLM QVDYHSGRDV LMLKADLGGL
1160 1170
RANYLLHAQR SPNPFDLALL RGFKLPATL
Length:1,179
Mass (Da):132,431
Last modified:March 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC4BE53D83C9DDF57
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CP003071 Genomic DNA Translation: AGA88715.1

NCBI Reference Sequences

More...
RefSeqi
WP_015278870.1, NC_019936.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AGA88715; AGA88715; Psest_4246

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
psh:Psest_4246

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|644801.3.peg.4145

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003071 Genomic DNA Translation: AGA88715.1
RefSeqiWP_015278870.1, NC_019936.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi644801.Psest_4246

Genome annotation databases

EnsemblBacteriaiAGA88715; AGA88715; Psest_4246
KEGGipsh:Psest_4246
PATRICifig|644801.3.peg.4145

Phylogenomic databases

HOGENOMiCLU_003353_2_1_6
KOiK11891
OrthoDBi393769at2

Enzyme and pathway databases

BioCyciPSTU644801:G1HDU-4187-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR027417 P-loop_NTPase
IPR017731 T6SS_IcmF
PfamiView protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03348 VI_IcmF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiL0GTK4_PSEST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: L0GTK4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: February 26, 2020
This is version 30 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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