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Protein

Alanine racemase

Gene

Osc7112_1877

Organism
Oscillatoria nigro-viridis PCC 7112
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (Osc7112_1877)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei63Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei162SubstrateUniRule annotation1
Active sitei291Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei339Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciONIG179408:G1HCR-1882-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:Osc7112_1877Imported
OrganismiOscillatoria nigro-viridis PCC 7112Imported
Taxonomic identifieri179408 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesOscillatoriaceaeOscillatoria
Proteomesi
  • UP000010478 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei63N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliK9VEI3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini270 – 398Ala_racemase_CInterPro annotationAdd BLAST129

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01775
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

K9VEI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSWEQTAAE SPTKESRQTL LWDGDGELCQ RAWVEIDLAA LTHNVKQLKK
60 70 80 90 100
LLSPHTELMA VVKADAYGHG AVAVSQTALQ AGASWLGVAT IPEGIELREA
110 120 130 140 150
GIEAPILLLG ATHTAQQVKA IAQWHLQPTI CTAKQALIFS EVLAGLNQSL
160 170 180 190 200
PVHAKLDTGM SRLGTPWQEA TEFVQLVKRL PNLKLASIYS HLATADSPDP
210 220 230 240 250
AVMREQHQRF QRAIEQIKIA GINPPRLHLA NSAAALADPD LHYDLVRVGL
260 270 280 290 300
ATYGLYPAPH LQPIANLKPA MQVKARVTQV KTIEAGTGVS YGYQFIAQRP
310 320 330 340 350
TQIAVIGIGY ADGIPRNLSN KIQVLVRGQF VRQVGAVTMD QLMLDVTDIP
360 370 380 390 400
DLEVGEVVTL LGKDGENQIT ADDWAVILGT ISWEILCGFK HRLPRVAVHY
Length:400
Mass (Da):43,574
Last modified:March 6, 2013 - v1
Checksum:iBD98D02CBF2D6E33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003614 Genomic DNA Translation: AFZ06361.1
RefSeqiWP_015175673.1, NC_019729.1

Genome annotation databases

EnsemblBacteriaiAFZ06361; AFZ06361; Osc7112_1877
KEGGioni:Osc7112_1877
PATRICifig|179408.3.peg.2280

Similar proteinsi

Entry informationi

Entry nameiK9VEI3_9CYAN
AccessioniPrimary (citable) accession number: K9VEI3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: February 28, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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