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UniProtKB - K9V5C5 (K9V5C5_9CYAN)

Entry version 35 (07 Oct 2020)
Sequence version 1 (06 Mar 2013)
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Protein
Submitted name:

Tetratricopeptide TPR_2 repeat-containing protein

Gene

Cal6303_3698

Organism
Calothrix sp. PCC 6303
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Tetratricopeptide TPR_2 repeat-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Cal6303_3698Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCalothrix sp. PCC 6303Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1170562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Cyanobacteria › Nostocales › Calotrichaceae › Calothrix ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010477 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		1170562.Cal6303_3698

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini552 – 862TPR_REGIONInterPro annotationAdd BLAST311
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati556 – 589TPRPROSITE-ProRule annotationAdd BLAST34
Repeati590 – 623TPRPROSITE-ProRule annotationAdd BLAST34
Repeati624 – 657TPRPROSITE-ProRule annotationAdd BLAST34
Repeati691 – 724TPRPROSITE-ProRule annotationAdd BLAST34
Repeati727 – 760TPRPROSITE-ProRule annotationAdd BLAST34
Repeati761 – 794TPRPROSITE-ProRule annotationAdd BLAST34
Repeati795 – 828TPRPROSITE-ProRule annotationAdd BLAST34
Repeati829 – 862TPRPROSITE-ProRule annotationAdd BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

TPR repeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG0265, Bacteria
COG0457, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_005774_2_0_3

Database of Orthologous Groups

More...OrthoDBi		21905at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 2 hits
2.40.10.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR013105, TPR_2
IPR019734, TPR_repeat

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00515, TPR_1, 1 hit
PF07719, TPR_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00028, TPR, 8 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452, SSF48452, 2 hits
SSF50494, SSF50494, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50005, TPR, 8 hits
PS50293, TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K9V5C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRKKLTWVVH HPRYRTLAVT AWMGTLLVLP LQVGELLISS PQVLAQPASA 
        60         70         80         90        100
QLSEAQIKQL AAAITVKVIA GENGGSGILI RKEAQKAGYL YTVVTNQHVL 
       110        120        130        140        150
EPGKAAQIQT GDGKKYPATL LKGVNFRGKD IALLQFSTNA NYTVSSLGNL 
       160        170        180        190        200
STVTVNEPIY SAGFPFEKKA NQNPFVFKSG KVLLVPERAF KEGYQIGYDN 
       210        220        230        240        250
TVEKGMSGGP ILNRRGQVIG INGIHAYPLW GNPYVYEDGS QPTAALKDLM 
       260        270        280        290        300
SRYSWGIPIQ TFAQLAPQYT SKESLPTGKT PVASKLPPIA NDVSNIAKEI 
       310        320        330        340        350
TVLIDVPSMP QCSGSGVIIS KQGNTYSVLS AEHVIRGSQK CDRTQLEIVT 
       360        370        380        390        400
SDGKRYPIQV NDRNVRSLPD SDLALLQFNS DQNYRTATLA NYNITGYDGF 
       410        420        430        440        450
IFVSGWQDTK AKNPALQHKF TAGNVVSKQL GSSILAKNSL SSSYGYGMIY 
       460        470        480        490        500
TNLTEQGMSG GPILDIRGRV IGIHGRSEVE SVKDQAGKNR LITLGFSLGV 
       510        520        530        540        550
PISDFINWSK SAGILSASKV ETTIAPALTQ PESDAILQSL LQPVKPQNNA 
       560        570        580        590        600
DAIDWVNYGW ELIRTSTSKT NTSESIQSFD KAIQLRPNFY QAWYLRGFVY 
       610        620        630        640        650
MTQNNYQESL KSFDKSVQIE PNFSTAWRWR GMILANLNKY QEALACFEQL 
       660        670        680        690        700
AKLDPGDSGA QTFRSIMLIG LQRFPEALEI AEKSLKQYPN SWNYFARGIA 
       710        720        730        740        750
RFGTKDQKGA LADLNEAIRL NPEAIEDTAY SVRATIRYAQ GDIQGALTDY 
       760        770        780        790        800
NEAIRLNPQK AEPILSRAAI HLQQKDYKSA VVDLNEAIRL KPEYREAFEL 
       810        820        830        840        850
RGTLYFLQNK HQEAVKDLTQ AIRLNSQNPD VYSIRGGAWL QLKDKKAASL 
       860        870 
DFQKAADLYK QQGNNERYQQ VLQAIKSLN
Length:879
Mass (Da):97,214
Last modified:March 6, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7A23AC540C905D0F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP003610 Genomic DNA Translation: AFZ02622.1

NCBI Reference Sequences

More...RefSeqi		WP_015199248.1, NC_019751.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AFZ02622; AFZ02622; Cal6303_3698

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		calt:Cal6303_3698

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1170562.3.peg.4026

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003610 Genomic DNA Translation: AFZ02622.1
RefSeqiWP_015199248.1, NC_019751.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi1170562.Cal6303_3698

Genome annotation databases

EnsemblBacteriaiAFZ02622; AFZ02622; Cal6303_3698
KEGGicalt:Cal6303_3698
PATRICifig|1170562.3.peg.4026

Phylogenomic databases

eggNOGiCOG0265, Bacteria
COG0457, Bacteria
HOGENOMiCLU_005774_2_0_3
OrthoDBi21905at2

Family and domain databases

Gene3Di1.25.40.10, 2 hits
2.40.10.10, 4 hits
InterProiView protein in InterPro
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR013105, TPR_2
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF00515, TPR_1, 1 hit
PF07719, TPR_2, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 8 hits
SUPFAMiSSF48452, SSF48452, 2 hits
SSF50494, SSF50494, 2 hits
PROSITEiView protein in PROSITE
PS50005, TPR, 8 hits
PS50293, TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK9V5C5_9CYAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K9V5C5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2013
Last sequence update: March 6, 2013
Last modified: October 7, 2020
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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