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Entry version 55 (29 Sep 2021)
Sequence version 4 (02 Jun 2021)
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Protein

[Histone H3]-trimethyl-L-lysine(4) demethylase

Gene

kdm5a

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Fe2+ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulatorARBA annotation, DioxygenaseARBA annotation, Oxidoreductase
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
[Histone H3]-trimethyl-L-lysine(4) demethylaseARBA annotation (EC:1.14.11.67ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:kdm5aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-996070, kdm5a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
K9J7Q2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000003642, Expressed in gastrula and 11 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000007871

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini13 – 54JmjNInterPro annotationAdd BLAST42
Domaini78 – 168ARIDInterPro annotationAdd BLAST91
Domaini179 – 229PHD-typeInterPro annotationAdd BLAST51
Domaini323 – 489JmjCInterPro annotationAdd BLAST167
Domaini1045 – 1102PHD-typeInterPro annotationAdd BLAST58
Domaini1491 – 1545PHD-typeInterPro annotationAdd BLAST55

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1207 – 1231DisorderedSequence analysisAdd BLAST25
Regioni1292 – 1318DisorderedSequence analysisAdd BLAST27
Regioni1369 – 1393DisorderedSequence analysisAdd BLAST25
Regioni1546 – 1582DisorderedSequence analysisAdd BLAST37

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili733 – 753Sequence analysisAdd BLAST21
Coiled coili825 – 845Sequence analysisAdd BLAST21
Coiled coili1426 – 1469Sequence analysisAdd BLAST44

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the JARID1 histone demethylase family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1246, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157170

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000991_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
K9J7Q2

TreeFam database of animal gene trees

More...
TreeFami
TF106476

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit
3.30.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR003347, JmjC_dom
IPR003349, JmjN
IPR013637, Lys_sp_deMease-like_dom
IPR019786, Zinc_finger_PHD-type_CS
IPR004198, Znf_C5HC2
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388, ARID, 1 hit
PF02373, JmjC, 1 hit
PF02375, JmjN, 1 hit
PF00628, PHD, 2 hits
PF08429, PLU-1, 1 hit
PF02928, zf-C5HC2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501, BRIGHT, 1 hit
SM00558, JmjC, 1 hit
SM00545, JmjN, 1 hit
SM00249, PHD, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774, SSF46774, 1 hit
SSF57903, SSF57903, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011, ARID, 1 hit
PS51184, JMJC, 1 hit
PS51183, JMJN, 1 hit
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

K9J7Q2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATYIEFVPP PECPVFEPSW EEFSDPLSFI GRIRPIAEKT GICKIRPPKD
60 70 80 90 100
WQPPFACDVK SFCFTPRVQR LNELEAMTRV KLDFLDQLGK FWELQGSALR
110 120 130 140 150
IPVVDRKLLD VYALSKVVSS EGGFEVVTKE KKWSQVGNRM GYQPGKGTGS
160 170 180 190 200
LLKLHYDRIL YPYELFQSGV SLMVRNVDLY ICLFCARGDC EDKLLLCDGC
210 220 230 240 250
DDSYHTFCLI PPLSEVPKGD WRCPKCVAEE CSKPREAFGF EQAVREYTLQ
260 270 280 290 300
SFGEMADSFK SDYFNMPVHM VPTELVEKEF WRLVSSIEED VIVEYGADIS
310 320 330 340 350
SRDFGSGFPV MDGRRKLTAD EEDYAHCGWN LNNMPVLEQS VLAHINADIS
360 370 380 390 400
GMKVPWLYVG MCFSSFCWHI EDHWSYSINY LHWGEPKTWY GVPSHAAEQL
410 420 430 440 450
EDVMRTLAPE LFETQPDLLH QLVTIMNPNV LMEHGVPVYR TNQCAGEFVI
460 470 480 490 500
TFPRAYHSGF NQGYNFAEAV NFCTADWLSM GRQCVSHYRR LRRHCVFSHE
510 520 530 540 550
ELIFKMASDP ECLDVGLAAA VCKEMTIMIE EETKLRELIV QLGVVQAEEE
560 570 580 590 600
AFELVPDDER QCSSCRTTCF LSALTCSCSL DQLVCLNHAE ELCSCPMQNK
610 620 630 640 650
CLRYRYSLED LPSLLYGVKL RAQSYESWVN RVTDALSASL NHKKDVIELK
660 670 680 690 700
VMLEDAEDRK FPENDLYRKL RDAVKEAETC ASVAQLLLTK KQKHNRLNPE
710 720 730 740 750
YGKTRTKLTM EELKAFVHQL FSLPCIISQA RQVKNLLDDV EEFHERAHEA
760 770 780 790 800
MRDDIPDSSK LQALIDLGSS LYVELPELPR LKQELLQARW LDEVRQTLSD
810 820 830 840 850
PHRVTLDVMK KLIDSGVGLA PHHAVEKAMA DLQELLTVSE RMEEKAKTCL
860 870 880 890 900
QARPQHSMGG IESIIVEAKN IHAYLPNVLA LKEALQRAKD WTAKVEAIQS
910 920 930 940 950
GSHYAYLEQL ENLLVKGRPI PVRLDALPQV ESQVAAARAW RERTARTFLK
960 970 980 990 1000
KNSSYTLLQV LSPRTDIGVY GSSRSKRKKV KELMDEKDLD LDSMSELEEP
1010 1020 1030 1040 1050
MEEPRDAASV VAVFKDMEHK EVDAIRSLRS ANLVKMTMVD RIEEVRFCVC
1060 1070 1080 1090 1100
RKAASGFMLQ CELCKDWFHS TCVPLPKTSS QKKGSNWQSK DVKFLCTQCM
1110 1120 1130 1140 1150
RSRRPRLETI LSLLVSLQKL PVRLPEGEAL QCLTERAMSW QDQARQALAT
1160 1170 1180 1190 1200
DELSCALAKL SVLSQRMVEQ AAREKTEKII SAELQKAAAN PDLQGHLPIF
1210 1220 1230 1240 1250
QQSSFSRGLS SMAPSPQTPL DYDDEETDSD EDIRETYGYD IKDSGSVKSS
1260 1270 1280 1290 1300
SSLEPNLFCD EEIPIKSEEV VSHMWTTSSF CAEHAYSSAS KSCVQGESTP
1310 1320 1330 1340 1350
RKQPRKSPLV PRSLEPPVLE LSPGAKCQLE ELLMLGDLLE VSLDETQHIW
1360 1370 1380 1390 1400
RILQATHPPS EEKFLHVMED DSLDEKPMKV KSKDSSEKKR KRKLERAEQL
1410 1420 1430 1440 1450
LAEGKQRSRE FKKLDKNKKK KLKLGHDKAK ELSKLAKRLA KEEERKRKKE
1460 1470 1480 1490 1500
KVAAAKAELS KEIAEKKREK KVLDIPSKYD WSGAEESDDE NAVCAAQNCQ
1510 1520 1530 1540 1550
RPCKDKVDWV QCDGGCDEWF HQVCVGVSSE MAENEDYICT NCSRKRVQGS
1560 1570 1580
GPPCPPCPSN LTFSPVLKEP GEAGDKCTKG TE
Length:1,582
Mass (Da):179,852
Last modified:June 2, 2021 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDE92A3C8394BCE2B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8RI64A0A6I8RI64_XENTR
[Histone H3]-trimethyl-L-lysine(4) ...
kdm5a
1,636Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SFL3A0A6I8SFL3_XENTR
[Histone H3]-trimethyl-L-lysine(4) ...
kdm5a
1,685Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8SJJ0A0A6I8SJJ0_XENTR
[Histone H3]-trimethyl-L-lysine(4) ...
kdm5a
1,618Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8Q4P8A0A6I8Q4P8_XENTR
[Histone H3]-trimethyl-L-lysine(4) ...
kdm5a
1,635Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_002942386.1, XM_002942340.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000007871; ENSXETP00000007871; ENSXETG00000003642

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100492975

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xtr:100492975

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_002942386.1, XM_002942340.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000007871

Proteomic databases

PaxDbiK9J7Q2

Genome annotation databases

EnsembliENSXETT00000007871; ENSXETP00000007871; ENSXETG00000003642
GeneIDi100492975
KEGGixtr:100492975

Organism-specific databases

XenbaseiXB-GENE-996070, kdm5a

Phylogenomic databases

eggNOGiKOG1246, Eukaryota
GeneTreeiENSGT00940000157170
HOGENOMiCLU_000991_2_0_1
InParanoidiK9J7Q2
TreeFamiTF106476

Gene expression databases

BgeeiENSXETG00000003642, Expressed in gastrula and 11 other tissues

Family and domain databases

Gene3Di1.10.150.60, 1 hit
3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR003347, JmjC_dom
IPR003349, JmjN
IPR013637, Lys_sp_deMease-like_dom
IPR019786, Zinc_finger_PHD-type_CS
IPR004198, Znf_C5HC2
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF01388, ARID, 1 hit
PF02373, JmjC, 1 hit
PF02375, JmjN, 1 hit
PF00628, PHD, 2 hits
PF08429, PLU-1, 1 hit
PF02928, zf-C5HC2, 1 hit
SMARTiView protein in SMART
SM00501, BRIGHT, 1 hit
SM00558, JmjC, 1 hit
SM00545, JmjN, 1 hit
SM00249, PHD, 3 hits
SUPFAMiSSF46774, SSF46774, 1 hit
SSF57903, SSF57903, 3 hits
PROSITEiView protein in PROSITE
PS51011, ARID, 1 hit
PS51184, JMJC, 1 hit
PS51183, JMJN, 1 hit
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 3 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK9J7Q2_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K9J7Q2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2013
Last sequence update: June 2, 2021
Last modified: September 29, 2021
This is version 55 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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