UniProtKB - K7U1I2 (K7U1I2_MAIZE)
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
ZEAMMB73_Zm00001d049649
Functioni
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
UniRule annotationARBA annotationCatalytic activityi
- EC:1.3.5.1ARBA annotation
Cofactori
Protein has several cofactor binding sites:- [2Fe-2S] clusterUniRule annotationNote: Binds 1 [2Fe-2S] cluster.UniRule annotation
- [3Fe-4S] clusterUniRule annotationNote: Binds 1 [3Fe-4S] cluster.UniRule annotation
- [4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster.UniRule annotation
: tricarboxylic acid cycle Pathwayi
This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotationARBA annotation This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.
GO - Molecular functioni
- 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
- 3 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
- electron transfer activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
- structural constituent of ribosome Source: InterPro
- succinate dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
GO - Biological processi
- aerobic respiration Source: GO_Central
- respiratory electron transport chain Source: GO_Central
- translation Source: InterPro
- tricarboxylic acid cycle Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal proteinARBA annotation |
Biological process | Tricarboxylic acid cycleARBA annotation |
Ligand | 2Fe-2SUniRule annotationARBA annotation, 3Fe-4SUniRule annotationARBA annotation, 4Fe-4SUniRule annotation, Iron, Iron-sulfur, Metal-binding |
Enzyme and pathway databases
UniPathwayi | UPA00223;UER01006 |
Names & Taxonomyi
Protein namesi | Recommended name: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation) |
Gene namesi | ORF Names:ZEAMMB73_Zm00001d049649Imported |
Organismi | Zea mays (Maize)Imported |
Taxonomic identifieri | 4577 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Tripsacinae › Zea |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Matrix side UniRule annotation
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
- mitochondrion Source: GO_Central
Other locations
- respiratory chain complex II Source: UniProt
- ribosome Source: UniProtKB-KW
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotationARBA annotationInteractioni
Subunit structurei
Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.
ARBA annotationProtein-protein interaction databases
STRINGi | 4577.GRMZM2G302259_P02 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1741, Eukaryota KOG3049, Eukaryota |
Family and domain databases
CDDi | cd00207, fer2, 1 hit |
Gene3Di | 1.10.1060.10, 1 hit 3.10.20.30, 1 hit 4.10.830.10, 1 hit |
InterProi | View protein in InterPro IPR036010, 2Fe-2S_ferredoxin-like_sf IPR001041, 2Fe-2S_ferredoxin-type IPR006058, 2Fe2S_fd_BS IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR012675, Beta-grasp_dom_sf IPR009051, Helical_ferredxn IPR001209, Ribosomal_S14 IPR043140, Ribosomal_S14/S29 IPR018271, Ribosomal_S14_CS IPR004489, Succ_DH/fum_Rdtase_Fe-S IPR025192, Succ_DH/fum_Rdtase_N |
Pfami | View protein in Pfam PF13085, Fer2_3, 1 hit PF00253, Ribosomal_S14, 1 hit |
SUPFAMi | SSF54292, SSF54292, 1 hit |
TIGRFAMsi | TIGR00384, dhsB, 1 hit |
PROSITEi | View protein in PROSITE PS00197, 2FE2S_FER_1, 1 hit PS51085, 2FE2S_FER_2, 1 hit PS00198, 4FE4S_FER_1, 1 hit PS51379, 4FE4S_FER_2, 1 hit PS00527, RIBOSOMAL_S14, 1 hit |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MAAALLRRSP AVRALLSPAL SSRLVASKPH SSSPAPPPPA KAASSTKTFS
60 70 80 90 100
IYRWDPDSPS TKPHLKDYQV DLSDCGPMVL DALLKIKNEQ DPSLTFRRSC
110 120 130 140 150
REGICGSCAM NIDGDNGLAC LTKISGASSA STVSPLPHMF VVKDLVVDMT
160 170 180 190 200
NFYSQYKSVE PWLKRKDQPP QQGKEIPQTK ADRAKLDGMY ECILCACCST
210 220 230 240 250
SCPSYWWNPE EYLGPAALLH ANRLPLWGTL IKPKPNMFMH LQARGYHGVS
260 270 280 290 300
EKRNLRDHKR RLLAEKYELR GKMYKAVCRD PDLPLDMREK FRYKLSKLPR
310 320 330 340 350
NSSMTRLRNR CIFTGRSRAV YKKFRMSRIV FRTLANKGEL MGVKKASWWI
360 370 380 390 400
QDSRDQFTKE RLDAINDEFK LYRCHTIKNC THACPKGLNP AKQIDTIKKL
QLGAPSA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000780 Genomic DNA Translation: AQK51001.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CM000780 Genomic DNA Translation: AQK51001.1 |
3D structure databases
AlphaFoldDBi | K7U1I2 |
SMRi | K7U1I2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4577.GRMZM2G302259_P02 |
Proteomic databases
PaxDbi | K7U1I2 |
Phylogenomic databases
eggNOGi | KOG1741, Eukaryota KOG3049, Eukaryota |
Enzyme and pathway databases
UniPathwayi | UPA00223;UER01006 |
Family and domain databases
CDDi | cd00207, fer2, 1 hit |
Gene3Di | 1.10.1060.10, 1 hit 3.10.20.30, 1 hit 4.10.830.10, 1 hit |
InterProi | View protein in InterPro IPR036010, 2Fe-2S_ferredoxin-like_sf IPR001041, 2Fe-2S_ferredoxin-type IPR006058, 2Fe2S_fd_BS IPR017896, 4Fe4S_Fe-S-bd IPR017900, 4Fe4S_Fe_S_CS IPR012675, Beta-grasp_dom_sf IPR009051, Helical_ferredxn IPR001209, Ribosomal_S14 IPR043140, Ribosomal_S14/S29 IPR018271, Ribosomal_S14_CS IPR004489, Succ_DH/fum_Rdtase_Fe-S IPR025192, Succ_DH/fum_Rdtase_N |
Pfami | View protein in Pfam PF13085, Fer2_3, 1 hit PF00253, Ribosomal_S14, 1 hit |
SUPFAMi | SSF54292, SSF54292, 1 hit |
TIGRFAMsi | TIGR00384, dhsB, 1 hit |
PROSITEi | View protein in PROSITE PS00197, 2FE2S_FER_1, 1 hit PS51085, 2FE2S_FER_2, 1 hit PS00198, 4FE4S_FER_1, 1 hit PS51379, 4FE4S_FER_2, 1 hit PS00527, RIBOSOMAL_S14, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | K7U1I2_MAIZE | |
Accessioni | K7U1I2Primary (citable) accession number: K7U1I2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 6, 2013 |
Last sequence update: | February 6, 2013 | |
Last modified: | May 25, 2022 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |