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Protein
Submitted name:

Gamma-aminobutyric acid type A receptor gamma2 subunit

Gene

GABRG2

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Gamma-aminobutyric acid type A receptor gamma2 subunitImported
Gene namesi
Name:GABRG2Imported
OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
Taxonomic identifieri13735 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
Proteomesi
  • UP000007267 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei313 – 337HelicalSequence analysisAdd BLAST25
Transmembranei378 – 401HelicalSequence analysisAdd BLAST24
Transmembranei488 – 507HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000019947

Structurei

3D structure databases

ProteinModelPortaliK7GI36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 313Neur_chan_LBDInterPro annotationAdd BLAST204
Domaini320 – 441Neur_chan_membInterPro annotationAdd BLAST122

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3642 Eukaryota
ENOG410XNQG LUCA
GeneTreeiENSGT00760000119010
OMAiYPGFTSQ
OrthoDBiEOG091G0805
TreeFamiTF315453

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006028 GABAA/Glycine_rcpt
IPR005439 GABBAg2_rcpt
IPR005437 GABBAg_rcpt
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00253 GABAARECEPTR
PR01620 GABAARGAMMA
PR01622 GABAARGAMMA2
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

K7GI36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCHPIDGTWW RETTSKVNIK KERDISICNQ EKKGQGEGRK REMSLPYPTS
60 70 80 90 100
LGSTALSNPA FSLKMMVWAL VLFSLIQCSS QKGDDDYEDY TSNKTWVLTP
110 120 130 140 150
KVHESDVTLI LNGLLEGYDN KLRPDIGVKP TVIHTDMYVN SIGPVNAINM
160 170 180 190 200
EYTIDIFFAQ TWYDRRLKFN STIKVLRLNS NMVGKIWIPD TFFRNSKKAD
210 220 230 240 250
AHWITTPNRM LRIWNDGRVL YTLRLTIDAE CQLQLHNFPM DEHSCPLEFS
260 270 280 290 300
SYGYPREEII YQWKRSSVEV GDTRSWRLYQ FSFIGLRNTT EVVKTTSGDY
310 320 330 340 350
VVMSVYFDLS RRMGYFTIQT YIPCTLIVVL SWVSFWINKD AVPARTSLGI
360 370 380 390 400
TTVLTMTTLS TIARKSLPKV SYVTAMDLFV SVCFIFVFSA LVEYGTLHYF
410 420 430 440 450
VSNRKPSKDK DKKKKNPAPT IDIRPRSATI QMNNATHLQE RDEEYGYECL
460 470 480 490 500
DGKDCASFFC CFEDCRTGAW RHGRIHIRIA KMDSYARIFF PTAFCLFNLV

YWVSYLYL
Length:508
Mass (Da):58,925
Last modified:January 9, 2013 - v1
Checksum:iC81D6D3D2B23210B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01007424 Genomic DNA No translation available.
AGCU01007425 Genomic DNA No translation available.
AGCU01007426 Genomic DNA No translation available.
AGCU01007427 Genomic DNA No translation available.
AGCU01007428 Genomic DNA No translation available.
AGCU01007429 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSPSIT00000020041; ENSPSIP00000019947; ENSPSIG00000017652

Similar proteinsi

Entry informationi

Entry nameiK7GI36_PELSI
AccessioniPrimary (citable) accession number: K7GI36
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: March 28, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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