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Protein

Phospholipid-transporting ATPase

Gene

ATP8B1

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipid-transporting ATPaseUniRule annotation (EC:3.6.3.1UniRule annotation)
Gene namesi
Name:ATP8B1Imported
OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
Taxonomic identifieri13735 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
Proteomesi
  • UP000007267 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei119 – 136HelicalUniRule annotationAdd BLAST18
Transmembranei142 – 161HelicalUniRule annotationAdd BLAST20
Transmembranei339 – 362HelicalUniRule annotationAdd BLAST24
Transmembranei389 – 408HelicalUniRule annotationAdd BLAST20
Transmembranei950 – 971HelicalUniRule annotationAdd BLAST22
Transmembranei983 – 1003HelicalUniRule annotationAdd BLAST21
Transmembranei1033 – 1052HelicalUniRule annotationAdd BLAST20
Transmembranei1072 – 1090HelicalUniRule annotationAdd BLAST19
Transmembranei1097 – 1115HelicalUniRule annotationAdd BLAST19
Transmembranei1144 – 1166HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000013221

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 145PhoLip_ATPase_NInterPro annotationAdd BLAST80
Domaini919 – 1173PhoLip_ATPase_CInterPro annotationAdd BLAST255

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili832 – 859Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITKD Eukaryota
ENOG410XPYK LUCA
GeneTreeiENSGT00910000144008
KOiK01530
OMAiARTQNTI
OrthoDBiEOG091G0139
TreeFamiTF300654

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
InterProiView protein in InterPro
IPR030346 ATP8B1
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PTHR24092:SF48 PTHR24092:SF48, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 2 hits
SSF81660 SSF81660, 2 hits
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

K7FYW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSDRDSETT FEEDSQPNDE VMPYSDDETE DELESQLPPV EPEQNRINRE
60 70 80 90 100
AEESRETVKK DCSWQVKAND RNFHEQPQFK KTTFLCIKKS KYAGNAIKTY
110 120 130 140 150
KYNPITFLPL NLLEQFKRVA NFYFLVLLIL QTIPQITTLS WYTTLVPLLL
160 170 180 190 200
VLGVTAIKDL VDDIARHRMD NEINNRTCDV IRDGRFKTAK WKDIQVGDVI
210 220 230 240 250
RLKKNAFVPA DILLLSSSEP NSLCYVETAE LDGETNLKFK MSPEITDRYL
260 270 280 290 300
QEESAMAEFD GVVECEEPNN RLDKFTGTLF WRGMSYSLDA DKILLRGCKT
310 320 330 340 350
RNTDFCHGLV IFAGADTKIM KNSGKTRFKR TKIDSLMNYM VYTIFILLIL
360 370 380 390 400
LSAGLAIGHT YWEQQIGNTS WYLYDGKDYS PPYRGFLNFW GYIIVLNTMV
410 420 430 440 450
PISLYVSVEV IRLGQSYFIN WDLQMYYPEK DIAAKARTTT LNEQLGQIHY
460 470 480 490 500
IFSDKTGTLT QNIMTFKKCC INGQTYGESR DEFGQPQNHE EQVDFSWNMY
510 520 530 540 550
ADGKLAFCDH YLIEQIRCGK EPEVRQLFFL LAICHTVMVD VSDGQLNYQA
560 570 580 590 600
ASPDEGALVT AARNFGFAFL SRTQNTITIS ELGIERTYDV LAILDFNSDR
610 620 630 640 650
KRMSVIVREP DGNVRLYCKG ADTVIYERLH PVNPQRQTTL EALDTFANET
660 670 680 690 700
LRTLCLCYKD ISHREYEAWN KKFMEASVAT NNRDEALDKV YEEIEKNLIL
710 720 730 740 750
LGATAIEDKL QDGVPETISK LAKSDIKIWV LTGDKKETAE NIGFSCELLT
760 770 780 790 800
DETTICYGED ISALLQTRLE NQNNGAGSTI NPSKRTNEPF FQSGRNRALI
810 820 830 840 850
ITGSWLNEIL LEKKKKKKKL PKLKFPRTEE EREKQIQSKR QAEANKEQQQ
860 870 880 890 900
RNFVDLACEC SAVICCRVTP KQKAMVVELV KKYKKAITLA IGDGANDVNM
910 920 930 940 950
IKTAHIGVGI SGQEGMQAVM SSDYSFGQFR YLQRLLLVHG RWSYIRMCKF
960 970 980 990 1000
LRYFFYKNFA FTLVHFWYSF FNGYSAQTAY EDWFITLYNV LYSSLPVLLV
1010 1020 1030 1040 1050
GLLDQDVSDK LSLRFPGLYV SGQRDLLFNY KKFFVSLIHG IITSLIIFFI
1060 1070 1080 1090 1100
PYGAYLQTMG QDGEAPSDYQ SFAVTAASSL VVAVNFQMGL DTSYWTFVNA
1110 1120 1130 1140 1150
FSIFGSIALY FGIMFDLHSA GIHVLFPASF QFTGTAPNAL RQPYLWLTIL
1160 1170 1180 1190 1200
LSVALCLLPV IALRFLSMTI WPSESDKIQK NRKKYKAEEQ WKRRQSAFRR
1210 1220 1230 1240 1250
GISSRRSAYA FSHQRGYADL IASGRSIRKK RAPLDAVVGH HVAETRQVGE

AS
Length:1,252
Mass (Da):143,431
Last modified:January 9, 2013 - v1
Checksum:iF7DE38928EAEADDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01042706 Genomic DNA No translation available.
AGCU01042707 Genomic DNA No translation available.
AGCU01042708 Genomic DNA No translation available.
AGCU01042709 Genomic DNA No translation available.
RefSeqiXP_006116626.1, XM_006116564.2
XP_006116627.1, XM_006116565.2
XP_006116628.1, XM_006116566.2
XP_006116629.1, XM_006116567.2

Genome annotation databases

EnsembliENSPSIT00000013284; ENSPSIP00000013221; ENSPSIG00000011891
GeneIDi102461705
KEGGipss:102461705

Similar proteinsi

Entry informationi

Entry nameiK7FYW1_PELSI
AccessioniPrimary (citable) accession number: K7FYW1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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