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Protein
Submitted name:

Uncharacterized protein

Gene

CHRNB1

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CHRNB1Imported
OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
Taxonomic identifieri13735 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
Proteomesi
  • UP000007267 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei238 – 262HelicalSequence analysisAdd BLAST25
Transmembranei269 – 287HelicalSequence analysisAdd BLAST19
Transmembranei299 – 324HelicalSequence analysisAdd BLAST26
Transmembranei462 – 480HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500390205421 – 493Sequence analysisAdd BLAST473

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 237Neur_chan_LBDInterPro annotationAdd BLAST213
Domaini244 – 479Neur_chan_membInterPro annotationAdd BLAST236

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645 Eukaryota
ENOG410XQGR LUCA
GeneTreeiENSGT00910000144023
KOiK04812

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

K7FRE7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARRAPVLVT LWLIPTVVVG SLQTEERLLE KLFENYNSNV RPARTLTDKV
60 70 80 90 100
FIRVGMSLSQ LISLNEKNEE LTTKVYMDLE WTDYRLSWNL SDFDYISSIR
110 120 130 140 150
LSSDKVWLPD IYLMNNNDGN VDIALPVNVL VSHVGTVQWL PPALYRSSCS
160 170 180 190 200
IQVTYFPFDW QNCSMVFQSY AYGATELGLL HPLDEAGREV QEIIIFENTF
210 220 230 240 250
IDNGQWEIRH KPARRNTLPG ELQHEDITFY LIIRRRPLFY IINVIIPCIL
260 270 280 290 300
ITILAIFVFY LPPDAGEKMT LSIFALLTLT VFLLLLADKV PETSLAVPII
310 320 330 340 350
VKYLMFTMIL VTFSVILSVV VLNLHHRSPN THDMPFWVRQ IFIHQLPRYL
360 370 380 390 400
GLQRPKPEPI LKPPPASKRE LVVKSNRSTD EYFIRKPTCD FLFPKPSRFY
410 420 430 440 450
QDPFLQDLRR FIDGPSECLV LPLDLKSAMD AVTYIAQQLQ DQEDYDTLKE
460 470 480 490
DWQYVAMVVD RLFLWTFITF TSVGTLTIFL DASCNLPPLH PFP
Length:493
Mass (Da):57,135
Last modified:January 9, 2013 - v1
Checksum:i61E4C09899550547
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7FRE1K7FRE1_PELSI
Uncharacterized protein
CHRNB1
497Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01013025 Genomic DNA No translation available.
AGCU01013026 Genomic DNA No translation available.
RefSeqiXP_006112165.1, XM_006112103.2

Genome annotation databases

EnsembliENSPSIT00000010660; ENSPSIP00000010607; ENSPSIG00000009407
GeneIDi102461595
KEGGipss:102461595

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01013025 Genomic DNA No translation available.
AGCU01013026 Genomic DNA No translation available.
RefSeqiXP_006112165.1, XM_006112103.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPSIT00000010660; ENSPSIP00000010607; ENSPSIG00000009407
GeneIDi102461595
KEGGipss:102461595

Organism-specific databases

CTDi1140

Phylogenomic databases

eggNOGiKOG3645 Eukaryota
ENOG410XQGR LUCA
GeneTreeiENSGT00910000144023
KOiK04812

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7FRE7_PELSI
AccessioniPrimary (citable) accession number: K7FRE7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: October 10, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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