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Protein
Submitted name:

Endothelin receptor type A

Gene

EDNRA

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Endothelin receptor type AImported
Gene namesi
Name:EDNRAImported
OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
Taxonomic identifieri13735 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
Proteomesi
  • UP000007267 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei75 – 100HelicalSequence analysisAdd BLAST26
Transmembranei112 – 134HelicalSequence analysisAdd BLAST23
Transmembranei154 – 175HelicalSequence analysisAdd BLAST22
Transmembranei187 – 212HelicalSequence analysisAdd BLAST26
Transmembranei251 – 277HelicalSequence analysisAdd BLAST27
Transmembranei298 – 316HelicalSequence analysisAdd BLAST19
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501409953521 – 421Sequence analysisAdd BLAST401

Interactioni

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000006983

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 363G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST273

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000119177
KOiK04197
OMAiYDEMDKN
OrthoDBiEOG091G0CJV
TreeFamiTF331292

Family and domain databases

InterProiView protein in InterPro
IPR000499 Endthln_rcpt
IPR002175 ETA_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00570 ENDOTHELINAR
PR00366 ENDOTHELINR
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

K7FG23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESFCLKVAL LFLVAGCVLS DSSDGYYANL SDSGNYLTTY SGIEPSLLLT
60 70 80 90 100
TIRPVVPNKT LYCAQRTKIA ATFKYINTVI SCIIFIIGLV GNATLLRIIY
110 120 130 140 150
QNKCMRNGPN ALIASLALGD LLYIVIDIPI NVYKLLAQRW PFGDSDFGLF
160 170 180 190 200
LCKFLPFIQK ASVGITVLNL CALSVDRYRA VASWSRVQGI GIPMITAIEI
210 220 230 240 250
FSIWILSFIL AIPEAIGFVM VPFKYKDEQI VTCMLNNTNK FITFYKNVKD
260 270 280 290 300
WWLFGFYFCV PLACTAVFYT LMTCEMLNRR NSNLRIALSE HLKQRREVAK
310 320 330 340 350
TVFCLVVIFA LCWFPLHLSR ILKKMVYNER DPNRCELLSF LLPLDYISIN
360 370 380 390 400
LATMNSCINP IALYFVSKKF KNCFQSCLCC CCYQSKSLTT SVPMNGTSIQ
410 420
WKNQELNNHN TDRSSHKDSI N
Length:421
Mass (Da):47,794
Last modified:January 9, 2013 - v1
Checksum:iF1699B09350FA52A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01157316 Genomic DNA No translation available.
AGCU01157317 Genomic DNA No translation available.
AGCU01157318 Genomic DNA No translation available.
RefSeqiXP_006133905.1, XM_006133843.2
XP_014434421.1, XM_014578935.1

Genome annotation databases

EnsembliENSPSIT00000007023; ENSPSIP00000006983; ENSPSIG00000006356
ENSPSIT00000007028; ENSPSIP00000006988; ENSPSIG00000006356
GeneIDi102455997
KEGGipss:102455997

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01157316 Genomic DNA No translation available.
AGCU01157317 Genomic DNA No translation available.
AGCU01157318 Genomic DNA No translation available.
RefSeqiXP_006133905.1, XM_006133843.2
XP_014434421.1, XM_014578935.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000006983

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPSIT00000007023; ENSPSIP00000006983; ENSPSIG00000006356
ENSPSIT00000007028; ENSPSIP00000006988; ENSPSIG00000006356
GeneIDi102455997
KEGGipss:102455997

Organism-specific databases

CTDi1909

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000119177
KOiK04197
OMAiYDEMDKN
OrthoDBiEOG091G0CJV
TreeFamiTF331292

Family and domain databases

InterProiView protein in InterPro
IPR000499 Endthln_rcpt
IPR002175 ETA_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00570 ENDOTHELINAR
PR00366 ENDOTHELINR
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7FG23_PELSI
AccessioniPrimary (citable) accession number: K7FG23
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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