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Entry version 34 (31 Jul 2019)
Sequence version 1 (09 Jan 2013)
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Protein
Submitted name:

ABI family member 3 binding protein

Gene

ABI3BP

Organism
Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ABI family member 3 binding proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABI3BPImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13735 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraTrionychiaTrionychidaePelodiscus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007267 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500390479922 – 1519Sequence analysisAdd BLAST1498

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
13735.ENSPSIP00000004221

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini114 – 212Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini1284 – 1377Fibronectin type-IIIInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni340 – 374DisorderedSequence analysisAdd BLAST35
Regioni529 – 564DisorderedSequence analysisAdd BLAST36
Regioni630 – 659DisorderedSequence analysisAdd BLAST30
Regioni674 – 703DisorderedSequence analysisAdd BLAST30
Regioni724 – 970DisorderedSequence analysisAdd BLAST247
Regioni992 – 1021DisorderedSequence analysisAdd BLAST30
Regioni1073 – 1102DisorderedSequence analysisAdd BLAST30
Regioni1137 – 1240DisorderedSequence analysisAdd BLAST104
Regioni1360 – 1383DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi360 – 374PolarSequence analysisAdd BLAST15
Compositional biasi784 – 798PolarSequence analysisAdd BLAST15
Compositional biasi1171 – 1197PolarSequence analysisAdd BLAST27
Compositional biasi1215 – 1237PolarSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIJU Eukaryota
ENOG410YEIJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063558

Identification of Orthologs from Complete Genome Data

More...
OMAi
PHTTPQF

TreeFam database of animal gene trees

More...
TreeFami
TF331037

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041 fn3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853 FN3, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

K7F861-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISRLVFLLF CGHIALNLGN AQKLPRGQNL KVQINTTDDT ICMKYLRLIP
60 70 80 90 100
NTKLHGFILG YGSSFFSNQY IPLPSEGKSY VTEVDAEPRY LITVRAAPVR
110 120 130 140 150
NHRKTCSGKT KTQKPLQLVV GTLTPNSVFL SWGILVNPQH DWTATSSCAS
160 170 180 190 200
DRFYTVRYRE KDKNKKWGFQ LCPTTETVVD NLKPNTLYEF GVKDNTEDGI
210 220 230 240 250
WSKIFNHKTI LSNKNKGNGH LQNTYKFIPN SQTQFIPGDG TKRVPITRIK
260 270 280 290 300
QVIQNITHRI LPKATDRPSL AGAILVHLIV PGLNETPPKF PKTLGMFETP
310 320 330 340 350
KKKLIMNETQ MWPAESKTPK VQEISPQSFP ATIESFQESI KPTVPAASEK
360 370 380 390 400
SDTSSDYNES ELESTKPNIA PTPELSLNTL AHSETESGLE ETNSTPKPEL
410 420 430 440 450
AQTQNILATT KPALKSSFPF METPETVMVS DETQIVSSRP KPSDIPEKLP
460 470 480 490 500
TKSVTIQTTM KTVTPEASKA EAVSYDFPPV ATTPQTAEIS EIFDLDSVTN
510 520 530 540 550
SADLETSEPL ISRIPHLLGT MALDDIQPVV SSPTTSDEPD ITDTKPAATS
560 570 580 590 600
EPTVESFSPK TSSALEWPRE TLAPNEIPLI PSKLKPYPLP EVQHVKPAQK
610 620 630 640 650
PLLLGQSTPK ASKTIEWSKT TLAPWETKFV TSTPKPSARP KMPQSKPAEK
660 670 680 690 700
SIHLESNTPK FSIPLELPRT TLAPSKTKLI PSKPKVSLHP EEPKSKPAAT
710 720 730 740 750
RKPIAVPVTS KISSVTATTE TLEHPKSTMV SYEPQHIPSK PKASASAIPE
760 770 780 790 800
MPHSKPAKSP ITPEATHKIS SNDLEWPRAT LAPTETQFIP SKPNTSPEPE
810 820 830 840 850
LLHSKPVLEP ITLRIEPPKS TIAPKETRRV PLKPKPSPKP HVPQTKPALE
860 870 880 890 900
STTFRTEQPK TPLAPKEVRR VPSKPKISPS PDVPQAKPAP KETQRVPSKP
910 920 930 940 950
KTSPIPDTPP TKAATKEIRR ITSRPKTLAS PEVPPTKPVP KEIQRIPSKL
960 970 980 990 1000
KTSASPDVPH TKPGIIPSIQ EPVTATAPYS LERAKATLAP KEIRLIPSKP
1010 1020 1030 1040 1050
KASVRPEAPQ TKPVPNETYP ISFKPQTALT TENPQLKTVS YVVRTETIKP
1060 1070 1080 1090 1100
KISKPFGKTE ATLAPHKVHL TPARPKISDK PQTRPVLNKT TPGPGRTKTA
1110 1120 1130 1140 1150
GVVRWGGTPT EVVRDSTKFL MGSNVSLESN VTRKKIDSVA IPPDSRHPPV
1160 1170 1180 1190 1200
APARPTQVRR KPLPPNTVTG KPGSPGISST SRASASSTTS AVRPTGPTKS
1210 1220 1230 1240 1250
LKTEKPRKKP TVSASPEEPV NTTVFSSSPT SETDVQGQPR FKAPYVVYMP
1260 1270 1280 1290 1300
KGDNEPCSIT STLEHFPEEE ASNKEDATNP PQNPPSNLTV VTVEGCPSFV
1310 1320 1330 1340 1350
VLNWTKPEND TVTEYKVVST ENGAPTGKEM SILTTNQTHS TVENLKPNTS
1360 1370 1380 1390 1400
YEFQVKAINP SGEGPPSDKV QFDTESADPR VSEPISMGKD AIWTEIPFNS
1410 1420 1430 1440 1450
NAYSECKGKQ YVKRTWYKKF VGVQLCNSLR YKIYLSDSLT GKFYSIGDQR
1460 1470 1480 1490 1500
GHGEDHCQFV DSFLDGRTGQ QVSSDQLPME DGFFRAVRQE PVKFGKIGGS
1510
THINYVHWYE CGTSIPGKW
Length:1,519
Mass (Da):166,810
Last modified:January 9, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9693484410C203BC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGCU01137157 Genomic DNA No translation available.
AGCU01137158 Genomic DNA No translation available.
AGCU01137159 Genomic DNA No translation available.
AGCU01137160 Genomic DNA No translation available.
AGCU01137161 Genomic DNA No translation available.
AGCU01137162 Genomic DNA No translation available.
AGCU01137163 Genomic DNA No translation available.
AGCU01137164 Genomic DNA No translation available.
AGCU01137165 Genomic DNA No translation available.
AGCU01137166 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPSIT00000004244; ENSPSIP00000004221; ENSPSIG00000003970

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGCU01137157 Genomic DNA No translation available.
AGCU01137158 Genomic DNA No translation available.
AGCU01137159 Genomic DNA No translation available.
AGCU01137160 Genomic DNA No translation available.
AGCU01137161 Genomic DNA No translation available.
AGCU01137162 Genomic DNA No translation available.
AGCU01137163 Genomic DNA No translation available.
AGCU01137164 Genomic DNA No translation available.
AGCU01137165 Genomic DNA No translation available.
AGCU01137166 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi13735.ENSPSIP00000004221

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPSIT00000004244; ENSPSIP00000004221; ENSPSIG00000003970

Phylogenomic databases

eggNOGiENOG410IIJU Eukaryota
ENOG410YEIJ LUCA
GeneTreeiENSGT00530000063558
OMAiPHTTPQF
TreeFamiTF331037

Family and domain databases

CDDicd00063 FN3, 2 hits
Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF00041 fn3, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK7F861_PELSI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: K7F861
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: July 31, 2019
This is version 34 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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