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Protein
Submitted name:

Ubiquitin carboxyl-terminal hydrolase 22

Gene

USP22

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin carboxyl-terminal hydrolase 22Imported
Gene namesi
Name:USP22Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000124422.11
HGNCiHGNC:12621 USP22

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000124422

PTM / Processingi

Proteomic databases

MaxQBiK7ESK0
PeptideAtlasiK7ESK0
PRIDEiK7ESK0

Expressioni

Gene expression databases

BgeeiENSG00000124422 Expressed in 239 organ(s), highest expression level in cerebellum
ExpressionAtlasiK7ESK0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ESK0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 107USPInterPro annotationAdd BLAST37

Phylogenomic databases

eggNOGiKOG1867 Eukaryota
ENOG410XQQ0 LUCA
GeneTreeiENSGT00890000139343

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR001394 Peptidase_C19_UCH
IPR018200 USP_CS
IPR028889 USP_dom
PfamiView protein in Pfam
PF00443 UCH, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00972 USP_1, 1 hit
PS50235 USP_3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

K7ESK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYGGIYCFLC QDYIYDKDME IIAKEEQRKA WKMQGVGEKF STWEPTKREL
60 70 80 90 100
ELLKHNPKRR KITSNCTIGL RGLINLGNTC FMNCIVQALT HTPLLRDFFL

SDRHRCE
Length:107
Mass (Da):12,650
Last modified:January 9, 2013 - v1
Checksum:i760E63E335FD67F0
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UPT9UBP22_HUMAN
Ubiquitin carboxyl-terminal hydrola...
USP22 KIAA1063, USP3L
525Annotation score:
K7ERX6K7ERX6_HUMAN
Ubiquitin carboxyl-terminal hydrola...
USP22
125Annotation score:
J3QS30J3QS30_HUMAN
Ubiquitin carboxyl-terminal hydrola...
USP22
102Annotation score:
J3QRV6J3QRV6_HUMAN
Ubiquitin carboxyl-terminal hydrola...
USP22
194Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei107Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087393 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000584538; ENSP00000468748; ENSG00000124422
UCSCiuc060crl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087393 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7ESK0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7ESK0
PeptideAtlasiK7ESK0
PRIDEiK7ESK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000584538; ENSP00000468748; ENSG00000124422
UCSCiuc060crl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000124422.11
HGNCiHGNC:12621 USP22
OpenTargetsiENSG00000124422
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1867 Eukaryota
ENOG410XQQ0 LUCA
GeneTreeiENSGT00890000139343

Miscellaneous databases

ChiTaRSiUSP22 human

Gene expression databases

BgeeiENSG00000124422 Expressed in 239 organ(s), highest expression level in cerebellum
ExpressionAtlasiK7ESK0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR038765 Papain_like_cys_pep_sf
IPR001394 Peptidase_C19_UCH
IPR018200 USP_CS
IPR028889 USP_dom
PfamiView protein in Pfam
PF00443 UCH, 1 hit
SUPFAMiSSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS00972 USP_1, 1 hit
PS50235 USP_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7ESK0_HUMAN
AccessioniPrimary (citable) accession number: K7ESK0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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