Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Keratin, type I cytoskeletal 17

Gene

KRT17

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin, type I cytoskeletal 17Imported
Gene namesi
Name:KRT17Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000128422.15
HGNCiHGNC:6427 KRT17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000128422

PTM / Processingi

Proteomic databases

MaxQBiK7ESE1
PeptideAtlasiK7ESE1
PRIDEiK7ESE1

Expressioni

Gene expression databases

BgeeiENSG00000128422 Expressed in 179 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiK7ESE1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ESE1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 95IF rodInterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili3 – 27Sequence analysisAdd BLAST25
Coiled coili44 – 68Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFTF Eukaryota
ENOG410Y9IV LUCA
GeneTreeiENSGT00900000140820

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR039008 IF_rod_dom
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PROSITEiView protein in PROSITE
PS51842 IF_ROD_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

K7ESE1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQIENLKEEL AYLKKNHEEE MNALRGQVGG EINVEMDAAP GVDLSRILNE
60 70 80 90
MRDQYEKMAE KNRKDAEDWF FSKTEELNRE VATNSELVQS GKSEI
Length:95
Mass (Da):10,991
Last modified:January 9, 2013 - v1
Checksum:iC5542B1E9BC7144F
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q04695K1C17_HUMAN
Keratin, type I cytoskeletal 17
KRT17
432Annotation score:
F5GWP8F5GWP8_HUMAN
Keratin, type I cytoskeletal 17
KRT17
349Annotation score:
K7EPJ9K7EPJ9_HUMAN
Keratin, type I cytoskeletal 17
KRT17
231Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei95Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130686 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000463128; ENSP00000468672; ENSG00000128422
UCSCiuc060fcf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130686 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7ESE1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7ESE1
PeptideAtlasiK7ESE1
PRIDEiK7ESE1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000463128; ENSP00000468672; ENSG00000128422
UCSCiuc060fcf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000128422.15
HGNCiHGNC:6427 KRT17
OpenTargetsiENSG00000128422
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFTF Eukaryota
ENOG410Y9IV LUCA
GeneTreeiENSGT00900000140820

Miscellaneous databases

ChiTaRSiKRT17 human

Gene expression databases

BgeeiENSG00000128422 Expressed in 179 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiK7ESE1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR039008 IF_rod_dom
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PROSITEiView protein in PROSITE
PS51842 IF_ROD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7ESE1_HUMAN
AccessioniPrimary (citable) accession number: K7ESE1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again