UniProtKB - K7ESD1 (K7ESD1_HUMAN)
Protein
DNA-directed RNA polymerase
Gene
POLRMT
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
- DNA-directed 5'-3' RNA polymerase activity Source: UniProtKB-KW
GO - Biological processi
- transcription, DNA-templated Source: InterPro
Keywordsi
Biological process | Transcription |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:POLRMTImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000099821.13 |
HGNCi | HGNC:9200, POLRMT |
Expressioni
Gene expression databases
Bgeei | ENSG00000099821, Expressed in left testis and 205 other tissues |
ExpressionAtlasi | K7ESD1, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 |
Sequence similaritiesi
Belongs to the phage and mitochondrial RNA polymerase family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00390000008060 |
HOGENOMi | CLU_1986600_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR002092, DNA-dir_Rpol_phage-type IPR043502, DNA/RNA_pol_sf |
PANTHERi | PTHR10102, PTHR10102, 1 hit |
Pfami | View protein in Pfam PF00940, RNA_pol, 1 hit |
SUPFAMi | SSF56672, SSF56672, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
K7ESD1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XPGLQGQANR RWNSEHHLHP QRRHQPPNTR KQKNGFPPNF IHSLDSSHMM
60 70 80 90 100
LTALHCYRKG LTFVSVHDCY WTHAADVSVM NQVCREQFVR LHSEPILQDL
110 120
SRFLVKRFCS EPQKILEASQ LKETLQA
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO00411 | RPOM_HUMAN | DNA-directed RNA polymerase, mitoch... | POLRMT | 1,230 | Annotation score: | ||
K7EMH3 | K7EMH3_HUMAN | DNA-directed RNA polymerase, mitoch... | POLRMT | 347 | Annotation score: | ||
R4GN79 | R4GN79_HUMAN | DNA-directed RNA polymerase, mitoch... | POLRMT | 56 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 127 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004449 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000590336; ENSP00000468658; ENSG00000099821 |
UCSCi | uc060qpm.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC004449 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | K7ESD1 |
PRIDEi | K7ESD1 |
Protocols and materials databases
Antibodypediai | 1270, 99 antibodies |
Genome annotation databases
Ensembli | ENST00000590336; ENSP00000468658; ENSG00000099821 |
UCSCi | uc060qpm.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000099821.13 |
HGNCi | HGNC:9200, POLRMT |
OpenTargetsi | ENSG00000099821 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000008060 |
HOGENOMi | CLU_1986600_0_0_1 |
Miscellaneous databases
ChiTaRSi | POLRMT, human |
Gene expression databases
Bgeei | ENSG00000099821, Expressed in left testis and 205 other tissues |
ExpressionAtlasi | K7ESD1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR002092, DNA-dir_Rpol_phage-type IPR043502, DNA/RNA_pol_sf |
PANTHERi | PTHR10102, PTHR10102, 1 hit |
Pfami | View protein in Pfam PF00940, RNA_pol, 1 hit |
SUPFAMi | SSF56672, SSF56672, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | K7ESD1_HUMAN | |
Accessioni | K7ESD1Primary (citable) accession number: K7ESD1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2013 |
Last sequence update: | October 29, 2014 | |
Last modified: | October 7, 2020 | |
This is version 36 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |