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Protein
Submitted name:

Galectin-3-binding protein

Gene

LGALS3BP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Galectin-3-binding proteinImported
Gene namesi
Name:LGALS3BPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000108679.12
HGNCiHGNC:6564 LGALS3BP

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000108679

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500390331919 – 88Sequence analysisAdd BLAST70

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiK7ES75
PRIDEiK7ES75

Expressioni

Gene expression databases

BgeeiENSG00000108679 Expressed in 221 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiK7ES75 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ES75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 88SRCRInterPro annotationAdd BLAST65

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IY2Y Eukaryota
ENOG410YBYF LUCA
GeneTreeiENSGT00530000063814

Family and domain databases

Gene3Di3.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 1 hit
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 1 hit
SUPFAMiSSF56487 SSF56487, 1 hit
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 1 hit
PS50287 SRCR_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

K7ES75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPPRLFWVW LLVAGTQGVN DGDMRLADGG ATNQGRVEIF YRGQWGTVCD
60 70 80
NLWDLTDASV VCRALGFENA TQALGRAAFG QGSGPIML
Length:88
Mass (Da):9,490
Last modified:January 9, 2013 - v1
Checksum:iA52FFF03DDF710D5
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q08380LG3BP_HUMAN
Galectin-3-binding protein
LGALS3BP M2BP
585Annotation score:
K7EJY8K7EJY8_HUMAN
Galectin-3-binding protein
LGALS3BP
144Annotation score:
K7EJD3K7EJD3_HUMAN
Galectin-3-binding protein
LGALS3BP
205Annotation score:
K7ESM3K7ESM3_HUMAN
Galectin-3-binding protein
LGALS3BP
209Annotation score:
K7EKQ5K7EKQ5_HUMAN
Galectin-3-binding protein
LGALS3BP
210Annotation score:
K7EP36K7EP36_HUMAN
Galectin-3-binding protein
LGALS3BP
259Annotation score:
K7ERZ6K7ERZ6_HUMAN
Galectin-3-binding protein
LGALS3BP
131Annotation score:
K7EN99K7EN99_HUMAN
Galectin-3-binding protein
LGALS3BP
113Annotation score:
K7EQT9K7EQT9_HUMAN
Galectin-3-binding protein
LGALS3BP
48Annotation score:
K7EM15K7EM15_HUMAN
Galectin-3-binding protein
LGALS3BP
62Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei88Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100788 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000591274; ENSP00000468586; ENSG00000108679
UCSCiuc060kxt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC100788 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7ES75
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiK7ES75
PRIDEiK7ES75

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000591274; ENSP00000468586; ENSG00000108679
UCSCiuc060kxt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000108679.12
HGNCiHGNC:6564 LGALS3BP
OpenTargetsiENSG00000108679
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IY2Y Eukaryota
ENOG410YBYF LUCA
GeneTreeiENSGT00530000063814

Miscellaneous databases

ChiTaRSiLGALS3BP human

Gene expression databases

BgeeiENSG00000108679 Expressed in 221 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiK7ES75 baseline and differential

Family and domain databases

Gene3Di3.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 1 hit
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 1 hit
SUPFAMiSSF56487 SSF56487, 1 hit
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 1 hit
PS50287 SRCR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7ES75_HUMAN
AccessioniPrimary (citable) accession number: K7ES75
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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