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Protein
Submitted name:

Formin-like protein 1

Gene

FMNL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Formin-like protein 1Imported
Gene namesi
Name:FMNL1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000184922.13
HGNCiHGNC:1212 FMNL1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei117 – 148HelicalSequence analysisAdd BLAST32

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184922

PTM / Processingi

Proteomic databases

PeptideAtlasiK7ERL1
PRIDEiK7ERL1

Expressioni

Gene expression databases

BgeeiENSG00000184922 Expressed in 190 organ(s), highest expression level in blood
ExpressionAtlasiK7ERL1 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ERL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili23 – 50Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118986

Family and domain databases

InterProiView protein in InterPro
IPR027657 FMNL1
PANTHERiPTHR23213:SF188 PTHR23213:SF188, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

K7ERL1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XRQDDCMVLK EFLRANSPTM DKLLADSKTA QKAEQEVEQW KKEAAAQEAG
60 70 80 90 100
ADTPGKGEPP APKSPPKARR PQMDLISELK RRQQKEPLIY ESDRDGAIED
110 120 130 140 150
IITGKGLARP WSYPQSVLLC FLLTQCAILW GTGCHTASCY LFCFSFLFPF

S
Length:151
Mass (Da):16,937
Last modified:October 5, 2016 - v8
Checksum:iE549B2360755E92A
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O95466FMNL1_HUMAN
Formin-like protein 1
FMNL1 C17orf1, C17orf1B, FMNL, FRL1
1,100Annotation score:
K7EK60K7EK60_HUMAN
Formin-like protein 1
FMNL1
682Annotation score:
K7EJE6K7EJE6_HUMAN
Formin-like protein 1
FMNL1
488Annotation score:
A0A0A0MR62A0A0A0MR62_HUMAN
Formin-like protein 1
FMNL1
626Annotation score:
K7EMY8K7EMY8_HUMAN
Formin-like protein 1
FMNL1
127Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei151Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008105 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000586092; ENSP00000468301; ENSG00000184922
UCSCiuc060ggo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008105 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7ERL1
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiK7ERL1
PRIDEiK7ERL1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000586092; ENSP00000468301; ENSG00000184922
UCSCiuc060ggo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000184922.13
HGNCiHGNC:1212 FMNL1
OpenTargetsiENSG00000184922
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118986

Miscellaneous databases

ChiTaRSiFMNL1 human

Gene expression databases

BgeeiENSG00000184922 Expressed in 190 organ(s), highest expression level in blood
ExpressionAtlasiK7ERL1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027657 FMNL1
PANTHERiPTHR23213:SF188 PTHR23213:SF188, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiK7ERL1_HUMAN
AccessioniPrimary (citable) accession number: K7ERL1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 35 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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