Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Transmembrane channel-like protein 6

Gene

TMC6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane channel-like protein 6Imported
Gene namesi
Name:TMC6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000141524.15
HGNCiHGNC:18021 TMC6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei205 – 224HelicalSequence analysisAdd BLAST20
Transmembranei245 – 271HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141524

PTM / Processingi

Proteomic databases

PeptideAtlasiK7ERH0
PRIDEiK7ERH0

Expressioni

Gene expression databases

BgeeiENSG00000141524
ExpressionAtlasiK7ERH0 baseline and differential

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IH09 Eukaryota
ENOG410XR0Y LUCA
GeneTreeiENSGT00760000119171

Family and domain databases

InterProiView protein in InterPro
IPR038900 TMC
PANTHERiPTHR23302 PTHR23302, 1 hit

Sequencei

Sequence statusi: Fragment.

K7ERH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQPLAFILD VPETPGDQGQ GPSPYDESEV HDSFQQLIQE QSQCTAQEGL
60 70 80 90 100
ELQQREREVT GSSQQTLWRP EGTQSTATLR ILASMPSRTI GRSRGAIISQ
110 120 130 140 150
YYNRTVQLRC RSSRPLLGNF VRSAWPSLRL YDLELDPTAL EEEEKQSLLV
160 170 180 190 200
KELQSLAVAQ RDHMLRGMPL SLAEKRSLRE KSRTPRGKWR GQPGSGGVCS
210 220 230 240 250
CCGRLRYACV LALHSLGLAL LSALQALMPW RYALKRIGGQ FGSSVLSYFL
260 270 280
FLKTLLAFNA LLLLLLVAFI MGPQVAFPPA LPGPA
Length:285
Mass (Da):31,582
Last modified:October 5, 2016 - v8
Checksum:i0B32B17FA5684520
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei285Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021593 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000589271; ENSP00000468255; ENSG00000141524
UCSCiuc060krx.1 human

Similar proteinsi

Entry informationi

Entry nameiK7ERH0_HUMAN
AccessioniPrimary (citable) accession number: K7ERH0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: October 5, 2016
Last modified: July 18, 2018
This is version 34 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health