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Protein
Submitted name:

DNA-binding protein RFX2

Gene

RFX2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein RFX2Imported
Gene namesi
Name:RFX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000087903.12
HGNCiHGNC:9983 RFX2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087903

PTM / Processingi

Proteomic databases

PeptideAtlasiK7EQU2

Expressioni

Gene expression databases

BgeeiENSG00000087903 Expressed in 199 organ(s), highest expression level in testis
ExpressionAtlasiK7EQU2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EQU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 124RFX1_trans_actInterPro annotationAdd BLAST100

Phylogenomic databases

GeneTreeiENSGT00550000074532

Family and domain databases

InterProiView protein in InterPro
IPR039779 RFX-like
IPR007668 RFX1_trans_act
PANTHERiPTHR12619 PTHR12619, 1 hit
PfamiView protein in Pfam
PF04589 RFX1_trans_act, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

K7EQU2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQNSEGGADS PASVALRPSA AAPPVPASPQ VQPVQHVYPA QVQYVEGGDA
60 70 80 90 100
VYTNGAIRTA YTYNPEPQMY APSSTASYFE APGGAQVTVA ASSPPAVPSH
110 120 130 140 150
SMVGITMDVG GSPIVSSAGA YLIHGGMDST RHSLAHTSRS SPATLEMAIE
160
NLQKSEGITS HKSGLLNSH
Length:169
Mass (Da):17,288
Last modified:January 9, 2013 - v1
Checksum:iDA4F7044A24C0582
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P48378RFX2_HUMAN
DNA-binding protein RFX2
RFX2
723Annotation score:
K7EJE4K7EJE4_HUMAN
DNA-binding protein RFX2
RFX2
99Annotation score:
K7ES56K7ES56_HUMAN
DNA-binding protein RFX2
RFX2
105Annotation score:
K7EIN5K7EIN5_HUMAN
DNA-binding protein RFX2
RFX2
142Annotation score:
K7ENC9K7ENC9_HUMAN
DNA-binding protein RFX2
RFX2
93Annotation score:
K7EQY9K7EQY9_HUMAN
DNA-binding protein RFX2
RFX2
110Annotation score:
K7EQA0K7EQA0_HUMAN
DNA-binding protein RFX2
RFX2
147Annotation score:
K7EJD4K7EJD4_HUMAN
DNA-binding protein RFX2
RFX2
33Annotation score:
K7ELD5K7ELD5_HUMAN
DNA-binding protein RFX2
RFX2
180Annotation score:
K7ELQ7K7ELQ7_HUMAN
DNA-binding protein RFX2
RFX2
98Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei169Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011444 Genomic DNA No translation available.
AC011471 Genomic DNA No translation available.
AC104538 Genomic DNA No translation available.
KF456482 Genomic DNA No translation available.
KF456484 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000586302; ENSP00000467979; ENSG00000087903
UCSCiuc060sgh.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011444 Genomic DNA No translation available.
AC011471 Genomic DNA No translation available.
AC104538 Genomic DNA No translation available.
KF456482 Genomic DNA No translation available.
KF456484 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EQU2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiK7EQU2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000586302; ENSP00000467979; ENSG00000087903
UCSCiuc060sgh.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000087903.12
HGNCiHGNC:9983 RFX2
OpenTargetsiENSG00000087903
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00550000074532

Miscellaneous databases

ChiTaRSiRFX2 human

Gene expression databases

BgeeiENSG00000087903 Expressed in 199 organ(s), highest expression level in testis
ExpressionAtlasiK7EQU2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR039779 RFX-like
IPR007668 RFX1_trans_act
PANTHERiPTHR12619 PTHR12619, 1 hit
PfamiView protein in Pfam
PF04589 RFX1_trans_act, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EQU2_HUMAN
AccessioniPrimary (citable) accession number: K7EQU2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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