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Protein
Submitted name:

Eukaryotic translation initiation factor 3 subunit K

Gene

EIF3K

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorSAAS annotation
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 3 subunit KImported
Gene namesi
Name:EIF3KImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000178982.9
HGNCiHGNC:24656 EIF3K

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000178982

PTM / Processingi

Proteomic databases

MaxQBiK7EQM4
PeptideAtlasiK7EQM4
PRIDEiK7EQM4

Expressioni

Gene expression databases

BgeeiENSG00000178982 Expressed in 240 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiK7EQM4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EQM4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 170PCIInterPro annotationAdd BLAST165

Phylogenomic databases

GeneTreeiENSGT00390000009409

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.25.40.250, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR033464 CSN8_PSD8_EIF3K
IPR009374 eIF3k
IPR000717 PCI_dom
IPR016020 Transl_init_fac_sub12_N_euk
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR13022 PTHR13022, 1 hit
PfamiView protein in Pfam
PF10075 CSN8_PSD8_EIF3K, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

K7EQM4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMFEQMRAN VGKLLKGIDR YQFNPAFFQT TVTAQILLKA LTNLPHTDFT
60 70 80 90 100
LCKCMIDQAH QEERPIRQIL YLGDLLETCH FQAFWQALDE NMDLLEGITG
110 120 130 140 150
FEDSVRKFIC HVVGITYQHI DRWLLAEMLG DLSDSQLKVW MSKYGWSADE
160 170
SGQIFICSQE ESIKPKNIVE
Length:170
Mass (Da):19,684
Last modified:January 9, 2013 - v1
Checksum:iD3A1F2589D9F66E9
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UBQ5EIF3K_HUMAN
Eukaryotic translation initiation f...
EIF3K EIF3S12, ARG134, HSPC029, MSTP001, PTD001
218Annotation score:
A0A087WVB9A0A087WVB9_HUMAN
Eukaryotic translation initiation f...
EIF3K EIF3S12, hCG_2040051
185Annotation score:
K7ERF1K7ERF1_HUMAN
Eukaryotic translation initiation f...
EIF3K EIF3S12, hCG_2040051
192Annotation score:
K7EK53K7EK53_HUMAN
Eukaryotic translation initiation f...
EIF3K
131Annotation score:
B4DQ48B4DQ48_HUMAN
Eukaryotic translation initiation f...
EIF3K
124Annotation score:
K7ES31K7ES31_HUMAN
Eukaryotic translation initiation f...
EIF3K
137Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei170Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008649 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000591409; ENSP00000467895; ENSG00000178982
UCSCiuc060ydu.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008649 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EQM4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7EQM4
PeptideAtlasiK7EQM4
PRIDEiK7EQM4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000591409; ENSP00000467895; ENSG00000178982
UCSCiuc060ydu.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000178982.9
HGNCiHGNC:24656 EIF3K
OpenTargetsiENSG00000178982
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000009409

Miscellaneous databases

ChiTaRSiEIF3K human

Gene expression databases

BgeeiENSG00000178982 Expressed in 240 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiK7EQM4 baseline and differential

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.25.40.250, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR033464 CSN8_PSD8_EIF3K
IPR009374 eIF3k
IPR000717 PCI_dom
IPR016020 Transl_init_fac_sub12_N_euk
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR13022 PTHR13022, 1 hit
PfamiView protein in Pfam
PF10075 CSN8_PSD8_EIF3K, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EQM4_HUMAN
AccessioniPrimary (citable) accession number: K7EQM4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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