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Protein

Rhomboid-like protein

Gene

RHBDF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, ProteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Rhomboid-like proteinUniRule annotation (EC:3.4.21.-UniRule annotation)
Gene namesi
Name:RHBDF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000129667.12
HGNCiHGNC:20788 RHBDF2

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000129667

PTM / Processingi

Proteomic databases

PeptideAtlasiK7EQ53
PRIDEiK7EQ53

Expressioni

Gene expression databases

BgeeiENSG00000129667 Expressed in 193 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiK7EQ53 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S54 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000012532

Family and domain databases

InterProiView protein in InterPro
IPR002610 Peptidase_S54_rhomboid
PANTHERiPTHR22936 PTHR22936, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

K7EQ53-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASADKNGGS VSSVSSSRLQ SRKPPNLSIT IPPPEKETQA PGEQDSMLPE
60 70 80
RKNPAYLKSV SLQEPRSRWQ ESSEKRPGFR RQASLSQSI
Length:89
Mass (Da):9,809
Last modified:October 5, 2016 - v8
Checksum:iE99AC24BD1F5DBDB
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6PJF5RHDF2_HUMAN
Inactive rhomboid protein 2
RHBDF2 IRHOM2, RHBDL5, RHBDL6
856Annotation score:
K7EPN8K7EPN8_HUMAN
Rhomboid-like protein
RHBDF2
86Annotation score:
K7EIY3K7EIY3_HUMAN
Rhomboid-like protein
RHBDF2
74Annotation score:
K7EKA3K7EKA3_HUMAN
Rhomboid-like protein
RHBDF2
73Annotation score:
K7EKI1K7EKI1_HUMAN
Rhomboid-like protein
RHBDF2
112Annotation score:
K7EQT5K7EQT5_HUMAN
Rhomboid-like protein
RHBDF2
47Annotation score:
K7EPV3K7EPV3_HUMAN
Inactive rhomboid protein
RHBDF2
185Annotation score:
K7EJ10K7EJ10_HUMAN
Inactive rhomboid protein 2
RHBDF2
28Annotation score:
K7ELA9K7ELA9_HUMAN
Inactive rhomboid protein 2
RHBDF2
26Annotation score:
K7EJD6K7EJD6_HUMAN
Inactive rhomboid protein 2
RHBDF2
13Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei89Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015802 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000589526; ENSP00000467677; ENSG00000129667
UCSCiuc060kjp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015802 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiK7EQ53
PRIDEiK7EQ53

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000589526; ENSP00000467677; ENSG00000129667
UCSCiuc060kjp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000129667.12
HGNCiHGNC:20788 RHBDF2
OpenTargetsiENSG00000129667
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000012532

Miscellaneous databases

ChiTaRSiRHBDF2 human

Gene expression databases

BgeeiENSG00000129667 Expressed in 193 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiK7EQ53 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002610 Peptidase_S54_rhomboid
PANTHERiPTHR22936 PTHR22936, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EQ53_HUMAN
AccessioniPrimary (citable) accession number: K7EQ53
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 38 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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