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Protein
Submitted name:

AFG3-like protein 2

Gene

AFG3L2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
AFG3-like protein 2Imported
Gene namesi
Name:AFG3L2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000141385.9
HGNCiHGNC:315 AFG3L2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 42HelicalSequence analysisAdd BLAST18
Transmembranei132 – 150HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141385

PTM / Processingi

Proteomic databases

EPDiK7EP56
MaxQBiK7EP56
PeptideAtlasiK7EP56
PRIDEiK7EP56

Expressioni

Gene expression databases

BgeeiENSG00000141385 Expressed in 234 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiK7EP56 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EP56
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 119FtsH_extInterPro annotationAdd BLAST91

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0731 Eukaryota
COG0465 LUCA
GeneTreeiENSGT00890000139410

Family and domain databases

InterProiView protein in InterPro
IPR011546 Pept_M41_FtsH_extracell
PfamiView protein in Pfam
PF06480 FtsH_ext, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

K7EP56-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVGPGEQPCL RTGDIPWDDK DFRMFFLWTA LFWGGVMFYL LLKRSGREIT
60 70 80 90 100
WKDFVNNYLS KGVVDRLEVV NKRFVRVTFT PGKTPVDGQY VWFNIGSVDT
110 120 130 140 150
FERNLETLQQ ELGIEGENRV PVVYIAESDG SFLLSMLPTV LIIAFLLYTI
160 170 180 190 200
RRGPAGIGRT GRGMGGLFSV GETTAKVLKD EIDVKFKDVA GCEEAKLEIM

EFVNFLKNP
Length:209
Mass (Da):23,659
Last modified:January 9, 2013 - v1
Checksum:iD0BB3E505BA90243
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y4W6AFG32_HUMAN
AFG3-like protein 2
AFG3L2
797Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei209Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001029 Genomic DNA No translation available.
AP005264 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000590811; ENSP00000467236; ENSG00000141385
UCSCiuc060nne.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001029 Genomic DNA No translation available.
AP005264 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EP56
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiK7EP56
MaxQBiK7EP56
PeptideAtlasiK7EP56
PRIDEiK7EP56

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000590811; ENSP00000467236; ENSG00000141385
UCSCiuc060nne.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000141385.9
HGNCiHGNC:315 AFG3L2
OpenTargetsiENSG00000141385
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0731 Eukaryota
COG0465 LUCA
GeneTreeiENSGT00890000139410

Miscellaneous databases

ChiTaRSiAFG3L2 human

Gene expression databases

BgeeiENSG00000141385 Expressed in 234 organ(s), highest expression level in primary visual cortex
ExpressionAtlasiK7EP56 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011546 Pept_M41_FtsH_extracell
PfamiView protein in Pfam
PF06480 FtsH_ext, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EP56_HUMAN
AccessioniPrimary (citable) accession number: K7EP56
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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