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Protein
Submitted name:

Centrosomal protein of 192 kDa

Gene

CEP192

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 192 kDaImported
Gene namesi
Name:CEP192Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000101639.18
HGNCiHGNC:25515 CEP192

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000101639

PTM / Processingi

Proteomic databases

MaxQBiK7ENP4
PRIDEiK7ENP4

Expressioni

Gene expression databases

BgeeiENSG00000101639 Expressed in 203 organ(s), highest expression level in heart
ExpressionAtlasiK7ENP4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7ENP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IG8G Eukaryota
ENOG4110RMB LUCA
GeneTreeiENSGT00510000048187

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR039103 Spd-2/CEP192
PANTHERiPTHR16029 PTHR16029, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

K7ENP4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGAECPHQNK TVLHMDGCLD TETPTVSIQE NVDVASLKPI SDSGINFTDA
60 70 80 90 100
IWSPTCERRT CECHESIEKN KDKTDLPQSV VYQNEEGRWV TDLAYYTSFN
110 120 130 140 150
SKQNLNVSLS DEMNEDFRSG SEAFDLIAQD EEEFNKEHQF IQPSFGYFIR
160 170 180 190 200
SPEKREPIAL IRKSDVSRGN LEKEMAHLNH DLYSGDLNEQ SQAQLSEGSI
210 220 230 240 250
TLQVEAVEST SQVDENDVTL TADKGKTEDT FFMSNKPQRY KDKLPDSGDS
260 270 280 290 300
MLRISTIASA IAEASVNTDP SQLAAMIKAL SNKTRDKTFQ EDEKQKDYSH
310 320 330 340 350
VRHFLPNDLE KSNGSNALDM EKYLKKTEVS RYESALENFS RASMSDTWDL
360 370 380 390 400
SLPKEQTTQD IHPVDLSATS VSVRAPEENT AAIVYVENGE SENQESFRTI
410 420 430 440 450
NSSNSVTNRE NNSAVVDVKT CSIDNKLQDV GNDEKATSIS TPSDSYSSVR
460 470 480 490 500
NPRITSLCLL KDCEEIRDNR ENQRQNECVS EISNSEKHVT FENHRIVSPK
510 520 530 540 550
NSDLKNTSPE HGGRGSEDEQ ESFRPSTSPL SHSSPSEISG TSSSGCALES
560 570 580 590 600
FGSAAQQQQP PCEQELSPLV CSPAGVSRLT YVSEPESSYP TTATDDALED
610 620 630 640 650
RKSDITSELS TTIIQGSPAA LEERAMEKLR EKVPFQNRGK GTLSSIIQNN
660 670 680 690 700
SDTRKATETT SLSSKPEYVK PDFRWSKDPS SKSGNLLETS EVGWTSNPEE
710 720 730 740 750
LDPIRLALLG KSGLSCQVGS ATSHPVSCQE PIDEDQRISP KDKSTAGREF
760 770 780 790 800
SGQVSHQTTS ENQCTPIPSS TVHSSVADMQ NMPAAVHALL TQPSLSAAPF
810 820 830 840 850
AQRYLGTLPS TGSTTLPQCH AGNATVCGFS GGLPYPAVAG EPVQNSVAVG
860 870 880 890 900
ICLGSNIGSG WMGTSSLCNP YSNTLNQNLL STTKPFPVPS VGTNCGIEPW
910 920 930 940 950
DSGVTSGLGS VRVPEELKLP HACCVGIASQ TLLSVLNPTD RWLQVSIGVL
960 970 980 990 1000
SISVNGEKVD LSTYRCLVFK NKAIIRPHAT EEIKVLFIPS SPGVFRCTFS
1010 1020 1030 1040 1050
VASWPCSTDA ETIVQAEALA STVTLTAIAE SPVIEVETEK KDVLDFGDLT
1060 1070 1080 1090 1100
YGGWKALPLK LINRTHATVP IRLIINANAV AWRCFTFSKE SVRAPVEVAP
1110 1120 1130 1140 1150
CADVVTRLAG PSVVNHMMPA SYDGQDPEFL MIWVLFHSPK KQISSSDILD
1160 1170 1180 1190 1200
SAEEFSAKVD IEVDSPNPTP VLRSVSLRAR AGIARIHAPR DLQTMHFLAK
1210 1220 1230 1240 1250
VASSRKQHLP LKNAGNIEVY LDIKVPEQGS HFSVDPKNLL LKPGEEHEVI
1260 1270 1280 1290 1300
VSFTPKDPEA CEERILKIFV QPFGPQYEVV LKGEVISSGS KPLSPGPCLD
1310 1320 1330 1340 1350
IPSILSNKQF LAWGGVPLGR TQLQKLALRN NSASTTQHLR LLIRGQDQDC
1360 1370 1380 1390 1400
FQLQNTFGSE QRLTSNCEIR IHPKEDIFIS VLFAPTRLSC MLARLEIKQL
1410 1420 1430 1440 1450
GNRSQPGIKF TIPLSGYGGT SNLILEGVKK LSDSYMVTVN GLVPGKESKI
1460 1470 1480 1490 1500
VFSVRNTGSR AAFVKAVGFK DSQKKVLLDP KVLRIFPDKF VLKERTQENV
1510 1520 1530 1540 1550
TLIYNPSDRG INNKTATELS TVYLFGGDEI SRQQYRRALL HKPEMIKQIL
1560 1570 1580 1590 1600
PEHSVLQNIN FVEAFQDELL VTEVYDLPQR PNDVQLFYGS MCKIILSVIG
1610 1620 1630 1640 1650
EFRDCISSRE FLQPSSKASL ESTSDLGASG KHGGNVSLDV LPVKGPQGSP
1660 1670 1680 1690 1700
LLSRAARPPL DQLASEEPWT VLPEHLILVA PSPCDMAKTG RFQIVNNSVR
1710 1720 1730 1740 1750
LLRFELCWPA HCLTVTPQHG CVAPESKLQI LVSPNSSLST KQSMFPWSGL
1760 1770 1780 1790 1800
IYIHCDDGQK KIVKVQIRED LTQVELLTRL TSKPFGILSP VSEPSVSHLV
1810 1820 1830 1840 1850
KPMTKPPSTK VEIRNKSITF PTTEPGETSE SCLELENHGT TDVKWHLSSL
1860 1870 1880 1890 1900
APPYVKGVDE SGDVFRATYA AFRCSPISGL LESHGIQKVS ITFLPRGRGD
1910 1920 1930 1940 1950
YAQFWDVECH PLKEPHMKHT LRFQLSGQSI EAENEPENAC LSTDSLIKID
1960 1970 1980 1990 2000
HLVKPRRQAV SEASARIPEQ LDVTARGVYA PEDVYRFRPT SVGESRTLKV
2010 2020 2030 2040 2050
NLRNNSFITH SLKFLSPREP FYVKHSKYSL RAQHYINMPV QFKPKSAGKF
2060 2070
EALLVIQTDE GKSIAIRLIG EALGKN
Length:2,076
Mass (Da):228,520
Last modified:January 9, 2013 - v1
Checksum:i029B7C23811602B7
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8TEP8CE192_HUMAN
Centrosomal protein of 192 kDa
CEP192 KIAA1569, PP8407
2,537Annotation score:
A0A0A0MR42A0A0A0MR42_HUMAN
Centrosomal protein of 192 kDa
CEP192
2,062Annotation score:
H0Y966H0Y966_HUMAN
Centrosomal protein of 192 kDa
CEP192
1,931Annotation score:
K7EPA2K7EPA2_HUMAN
Centrosomal protein of 192 kDa
CEP192
900Annotation score:
C9JT09C9JT09_HUMAN
Centrosomal protein of 192 kDa
CEP192
426Annotation score:
K7ELX0K7ELX0_HUMAN
Centrosomal protein of 192 kDa
CEP192
1,237Annotation score:
K7ERF9K7ERF9_HUMAN
Centrosomal protein of 192 kDa
CEP192
73Annotation score:
K7EQZ8K7EQZ8_HUMAN
Centrosomal protein of 192 kDa
CEP192
47Annotation score:
H0Y9P3H0Y9P3_HUMAN
Centrosomal protein of 192 kDa
CEP192
407Annotation score:
V9GYM2V9GYM2_HUMAN
Centrosomal protein of 192 kDa
CEP192
70Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001357 Genomic DNA No translation available.
AP002449 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000511820; ENSP00000467038; ENSG00000101639
UCSCiuc060npr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001357 Genomic DNA No translation available.
AP002449 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7ENP4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7ENP4
PRIDEiK7ENP4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000511820; ENSP00000467038; ENSG00000101639
UCSCiuc060npr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000101639.18
HGNCiHGNC:25515 CEP192
OpenTargetsiENSG00000101639
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IG8G Eukaryota
ENOG4110RMB LUCA
GeneTreeiENSGT00510000048187

Miscellaneous databases

ChiTaRSiCEP192 human

Gene expression databases

BgeeiENSG00000101639 Expressed in 203 organ(s), highest expression level in heart
ExpressionAtlasiK7ENP4 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR039103 Spd-2/CEP192
PANTHERiPTHR16029 PTHR16029, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7ENP4_HUMAN
AccessioniPrimary (citable) accession number: K7ENP4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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