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Protein
Submitted name:

DNA-binding protein RFXANK

Gene

RFXANK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein RFXANKImported
Gene namesi
Name:RFXANKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000064490.13
HGNCiHGNC:9987 RFXANK

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000064490

PTM / Processingi

Proteomic databases

MaxQBiK7ENE6
PeptideAtlasiK7ENE6
PRIDEiK7ENE6

Expressioni

Gene expression databases

BgeeiENSG00000064490 Expressed in 217 organ(s), highest expression level in body of stomach
ExpressionAtlasiK7ENE6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 145ANK_REP_REGIONInterPro annotationAdd BLAST58
Repeati122 – 145ANKPROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0502 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00930000150856

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

K7ENE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELTQPAEDL IQTQQTPASE LGDPEDPGEE AADGSDTVVL SLFPCTPEPV
60 70 80 90 100
NPEPDASVSS PQGSSLKHST TLTNRQRGNE VSALPATLDS LSIHQLAAQG
110 120 130 140
ELDQLKEHLR KGDNLVNKPD ERGFTPLIWA SAFGEIETVR FLLEW
Length:145
Mass (Da):15,715
Last modified:January 9, 2013 - v1
Checksum:i40E9A9E67482563D
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O14593RFXK_HUMAN
DNA-binding protein RFXANK
RFXANK ANKRA1, RFXB
260Annotation score:
A0A024R7P0A0A024R7P0_HUMAN
DNA-binding protein RFXANK
RFXANK hCG_38560
237Annotation score:
F5GY33F5GY33_HUMAN
DNA-binding protein RFXANK
RFXANK
188Annotation score:
F5H7D2F5H7D2_HUMAN
DNA-binding protein RFXANK
RFXANK
83Annotation score:
H0YGQ6H0YGQ6_HUMAN
DNA-binding protein RFXANK
RFXANK
182Annotation score:
H0YFZ0H0YFZ0_HUMAN
DNA-binding protein RFXANK
RFXANK
47Annotation score:
H0YFU5H0YFU5_HUMAN
DNA-binding protein RFXANK
RFXANK
41Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei145Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002126 Genomic DNA No translation available.
AC003110 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000593273; ENSP00000466913; ENSG00000064490
UCSCiuc060vyf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002126 Genomic DNA No translation available.
AC003110 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7ENE6
PeptideAtlasiK7ENE6
PRIDEiK7ENE6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000593273; ENSP00000466913; ENSG00000064490
UCSCiuc060vyf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000064490.13
HGNCiHGNC:9987 RFXANK
OpenTargetsiENSG00000064490
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0502 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00930000150856

Gene expression databases

BgeeiENSG00000064490 Expressed in 217 organ(s), highest expression level in body of stomach
ExpressionAtlasiK7ENE6 baseline and differential

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7ENE6_HUMAN
AccessioniPrimary (citable) accession number: K7ENE6
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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