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Protein
Submitted name:

Probable ATP-dependent RNA helicase DHX58

Gene

DHX58

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Probable ATP-dependent RNA helicase DHX58Imported
Gene namesi
Name:DHX58Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000108771.12
HGNCiHGNC:29517 DHX58

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000108771

PTM / Processingi

Proteomic databases

PeptideAtlasiK7EMZ5

Expressioni

Gene expression databases

BgeeiENSG00000108771 Expressed in 105 organ(s), highest expression level in left adrenal gland
ExpressionAtlasiK7EMZ5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EMZ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 99Helicase ATP-bindingInterPro annotationAdd BLAST99

Phylogenomic databases

eggNOGiKOG0354 Eukaryota
COG1111 LUCA
GeneTreeiENSGT00510000046789

Family and domain databases

InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

K7EMZ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDGRWTVTT LSGDMGPRAG FGHLARCHDL LICTAELLQM ALTSPEEEEH
60 70 80 90
VELTVFSLIV VDECHHTHKD TVYNVIMSQY LELKLQRAQP LPQVLGLTA
Length:99
Mass (Da):11,085
Last modified:January 9, 2013 - v1
Checksum:i475A5CF10674BFCB
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96C10DHX58_HUMAN
Probable ATP-dependent RNA helicase...
DHX58 D11LGP2E, LGP2
678Annotation score:
C9JG98C9JG98_HUMAN
Probable ATP-dependent RNA helicase...
DHX58
302Annotation score:
C9JE76C9JE76_HUMAN
Probable ATP-dependent RNA helicase...
DHX58
156Annotation score:
K7EPP0K7EPP0_HUMAN
Probable ATP-dependent RNA helicase...
DHX58
51Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei99Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105024 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000591220; ENSP00000466721; ENSG00000108771
UCSCiuc060fgs.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105024 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EMZ5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiK7EMZ5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000591220; ENSP00000466721; ENSG00000108771
UCSCiuc060fgs.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000108771.12
HGNCiHGNC:29517 DHX58
OpenTargetsiENSG00000108771
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0354 Eukaryota
COG1111 LUCA
GeneTreeiENSGT00510000046789

Miscellaneous databases

ChiTaRSiDHX58 human

Gene expression databases

BgeeiENSG00000108771 Expressed in 105 organ(s), highest expression level in left adrenal gland
ExpressionAtlasiK7EMZ5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EMZ5_HUMAN
AccessioniPrimary (citable) accession number: K7EMZ5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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