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Protein
Submitted name:

Guanine nucleotide-binding protein subunit alpha-11

Gene

GNA11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein subunit alpha-11Imported
Gene namesi
Name:GNA11Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000088256.8
HGNCiHGNC:4379 GNA11

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000088256

PTM / Processingi

Proteomic databases

EPDiK7EL62
MaxQBiK7EL62
PeptideAtlasiK7EL62
PRIDEiK7EL62

Expressioni

Gene expression databases

BgeeiENSG00000088256 Expressed in 238 organ(s), highest expression level in colonic mucosa
ExpressionAtlasiK7EL62 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliK7EL62
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0085 Eukaryota
ENOG410XNVQ LUCA
GeneTreeiENSGT00760000118851

Family and domain databases

CDDicd00066 G-alpha, 1 hit
InterProiView protein in InterPro
IPR000654 Gprotein_alpha_Q
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase
PANTHERiPTHR10218 PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503 G-alpha, 1 hit
PRINTSiPR00318 GPROTEINA
PR00442 GPROTEINAQ
SMARTiView protein in SMART
SM00275 G_alpha, 1 hit
SUPFAMiSSF47895 SSF47895, 1 hit
SSF52540 SSF52540, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

K7EL62-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XLSDSAKYYL TDVDRIATLG YLPTQQDVLR VRVPTTGIIE YPFDLENIIF
60 70 80 90 100
RMVDVGGQRS ERRKWIHCFE NVTSIMFLVA LSEYDQVLVE SDNENRMEES
110 120 130 140 150
KALFRTIITY PWFQNSSVIL FLNKKDLLED KILYSHLVDY FPEFDGPQRD
160 170 180 190 200
AQAAREFILK MFVDLNPDSD KIIYSHFTCA TDTENIRFVF AAVKDTILQL
210 220 230
NLKEYNLLSG DVHLSLRTLR APSHLLSTAK AAFFWP
Length:236
Mass (Da):27,434
Last modified:January 9, 2013 - v1
Checksum:i73A5073958D60E44
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P29992GNA11_HUMAN
Guanine nucleotide-binding protein ...
GNA11 GA11
359Annotation score:
A0A087WVZ3A0A087WVZ3_HUMAN
Guanine nucleotide-binding protein ...
GNA11
72Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005262 Genomic DNA No translation available.
KF456478 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000587636; ENSP00000465935; ENSG00000088256
UCSCiuc060roh.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005262 Genomic DNA No translation available.
KF456478 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EL62
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiK7EL62
MaxQBiK7EL62
PeptideAtlasiK7EL62
PRIDEiK7EL62

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000587636; ENSP00000465935; ENSG00000088256
UCSCiuc060roh.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000088256.8
HGNCiHGNC:4379 GNA11
OpenTargetsiENSG00000088256
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0085 Eukaryota
ENOG410XNVQ LUCA
GeneTreeiENSGT00760000118851

Miscellaneous databases

ChiTaRSiGNA11 human

Gene expression databases

BgeeiENSG00000088256 Expressed in 238 organ(s), highest expression level in colonic mucosa
ExpressionAtlasiK7EL62 baseline and differential

Family and domain databases

CDDicd00066 G-alpha, 1 hit
InterProiView protein in InterPro
IPR000654 Gprotein_alpha_Q
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase
PANTHERiPTHR10218 PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503 G-alpha, 1 hit
PRINTSiPR00318 GPROTEINA
PR00442 GPROTEINAQ
SMARTiView protein in SMART
SM00275 G_alpha, 1 hit
SUPFAMiSSF47895 SSF47895, 1 hit
SSF52540 SSF52540, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EL62_HUMAN
AccessioniPrimary (citable) accession number: K7EL62
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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