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Protein
Submitted name:

Unconventional myosin-XV

Gene

MYO15A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Unconventional myosin-XVImported
Gene namesi
Name:MYO15AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000091536.16
HGNCiHGNC:7594 MYO15A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000091536

Expressioni

Gene expression databases

BgeeiENSG00000091536 Expressed in 110 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiK7EL45 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EL45
SMRiK7EL45
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 109MyTH4InterPro annotationAdd BLAST109

Phylogenomic databases

eggNOGiKOG4229 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00900000140810

Family and domain databases

Gene3Di1.25.40.530, 1 hit
InterProiView protein in InterPro
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
PfamiView protein in Pfam
PF00784 MyTH4, 1 hit
SMARTiView protein in SMART
SM00139 MyTH4, 1 hit
PROSITEiView protein in PROSITE
PS51016 MYTH4, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

K7EL45-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LCNLLKLCGD HEVMRDECYC QVVKQITDNT SSKQDSCQRG WRLLYIVTAY
60 70 80 90 100
HSCSEVLHPH LTRFLQDVSR TPGLPFQGIA KACEQNLQKT LRFGGRLELP
110 120 130 140 150
SSIELRAMLA GRSSKRQLFL LPGGLERHLK IKTCTVALDV VEEICAEMAL
160 170 180 190 200
TRPEAFNEYV IFVVTNRGGK SRSTSQPSST VQRQARPGST WSASTGSRHR
210 220 230 240 250
RSAPTRPVPS FWASSAPYLC SAPPSSSSRA AATLLCQPLA SLPSTTMAST

FSAQRLM
Length:257
Mass (Da):28,335
Last modified:January 9, 2013 - v1
Checksum:iC228C6356E704738
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UKN7MYO15_HUMAN
Unconventional myosin-XV
MYO15A MYO15
3,530Annotation score:
A0A087WYA1A0A087WYA1_HUMAN
Unconventional myosin-XV
MYO15A
3,530Annotation score:
A0A2R8Y712A0A2R8Y712_HUMAN
Unconventional myosin-XV
MYO15A
716Annotation score:
K7EQV1K7EQV1_HUMAN
Unconventional myosin-XV
MYO15A
123Annotation score:
G3V4G3G3V4G3_HUMAN
Unconventional myosin-XV
MYO15A
153Annotation score:
K7EMS7K7EMS7_HUMAN
Unconventional myosin-XV
MYO15A
120Annotation score:
G3V4Q3G3V4Q3_HUMAN
Unconventional myosin-XV
MYO15A
35Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087164 Genomic DNA No translation available.
KF456256 Genomic DNA No translation available.
KF456257 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000579848; ENSP00000465910; ENSG00000091536
UCSCiuc060cbm.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087164 Genomic DNA No translation available.
KF456256 Genomic DNA No translation available.
KF456257 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EL45
SMRiK7EL45
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000579848; ENSP00000465910; ENSG00000091536
UCSCiuc060cbm.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000091536.16
HGNCiHGNC:7594 MYO15A
OpenTargetsiENSG00000091536
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4229 Eukaryota
COG5022 LUCA
GeneTreeiENSGT00900000140810

Miscellaneous databases

ChiTaRSiMYO15A human

Gene expression databases

BgeeiENSG00000091536 Expressed in 110 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiK7EL45 baseline and differential

Family and domain databases

Gene3Di1.25.40.530, 1 hit
InterProiView protein in InterPro
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
PfamiView protein in Pfam
PF00784 MyTH4, 1 hit
SMARTiView protein in SMART
SM00139 MyTH4, 1 hit
PROSITEiView protein in PROSITE
PS51016 MYTH4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EL45_HUMAN
AccessioniPrimary (citable) accession number: K7EL45
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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