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Protein
Submitted name:

Modulator of macroautophagy TMEM150B

Gene

TMEM150B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Modulator of macroautophagy TMEM150BImported
Gene namesi
Name:TMEM150BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000180061.9
HGNCiHGNC:34415 TMEM150B

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei44 – 62HelicalSequence analysisAdd BLAST19
Transmembranei74 – 93HelicalSequence analysisAdd BLAST20
Transmembranei105 – 126HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000180061

Expressioni

Gene expression databases

BgeeiENSG00000180061 Expressed in 89 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiK7EKL2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EKL2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4320 Eukaryota
ENOG4111KNB LUCA
GeneTreeiENSGT00730000110794

Family and domain databases

InterProiView protein in InterPro
IPR019402 Frag1/DRAM/Sfk1
PfamiView protein in Pfam
PF10277 Frag1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

K7EKL2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
GSFPPQSCIF SQVLNMGAAL AAWICIVRYH QLRDWGVRRW PNQLILWTGL
60 70 80 90 100
LCALGTSVVG NFQEKNQRPT HLAGAFLAFI LGNVYFWLQL LLWRLKRLPQ
110 120 130 140 150
PGAAWIGPLR LGLCSVCTIL IVAMIVLHAC SLRSVSAACE WVVAMLLFAL

FG
Length:152
Mass (Da):16,922
Last modified:April 3, 2013 - v2
Checksum:i67A2EBEA6E527406
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6NC51T150B_HUMAN
Modulator of macroautophagy TMEM150...
TMEM150B TMEM224
233Annotation score:
K7EM00K7EM00_HUMAN
Modulator of macroautophagy TMEM150...
TMEM150B
134Annotation score:
K7EKW5K7EKW5_HUMAN
Modulator of macroautophagy TMEM150...
TMEM150B
84Annotation score:
K7ENI3K7ENI3_HUMAN
Modulator of macroautophagy TMEM150...
TMEM150B
63Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei152Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020922 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000585918; ENSP00000465672; ENSG00000180061
UCSCiuc061czk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020922 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EKL2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000585918; ENSP00000465672; ENSG00000180061
UCSCiuc061czk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000180061.9
HGNCiHGNC:34415 TMEM150B
OpenTargetsiENSG00000180061
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4320 Eukaryota
ENOG4111KNB LUCA
GeneTreeiENSGT00730000110794

Gene expression databases

BgeeiENSG00000180061 Expressed in 89 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiK7EKL2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR019402 Frag1/DRAM/Sfk1
PfamiView protein in Pfam
PF10277 Frag1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EKL2_HUMAN
AccessioniPrimary (citable) accession number: K7EKL2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 27 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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