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UniProtKB - K7EKK2 (K7EKK2_HUMAN)
Protein
Submitted name:
Beclin-1
Gene
BECN1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- autophagy Source: InterPro
- endocytosis Source: InterPro
- regulation of cytokinesis Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Beclin-1 |
Gene namesi | Name:BECN1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:1034, BECN1 |
VEuPathDBi | HostDB:ENSG00000126581 |
Expressioni
Gene expression databases
Bgeei | ENSG00000126581, Expressed in frontal cortex and 243 other tissues |
ExpressionAtlasi | K7EKK2, baseline and differential |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 43 – 76 | DisorderedSequence analysisAdd BLAST | 34 |
Phylogenomic databases
GeneTreei | ENSGT00390000008164 |
HOGENOMi | CLU_2653822_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR007243, Atg6/Beclin IPR032913, BECN1 |
PANTHERi | PTHR12768, PTHR12768, 1 hit PTHR12768:SF6, PTHR12768:SF6, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
K7EKK2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGSKTSNNS TMQVSFVCQR CSQPLKLDTS FKILDRVTIQ ELTGQRDPWK
60 70
EGGQECGSSI TYHSPGETRR DPGGRD
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ14457 | BECN1_HUMAN | Beclin-1 | BECN1 GT197 | 450 | Annotation score: | ||
E7EV84 | E7EV84_HUMAN | Beclin-1 | BECN1 | 279 | Annotation score: | ||
K7ER46 | K7ER46_HUMAN | Beclin-1 | BECN1 | 132 | Annotation score: | ||
K7ELY9 | K7ELY9_HUMAN | Beclin-1 | BECN1 | 229 | Annotation score: | ||
K7EN35 | K7EN35_HUMAN | Beclin-1 | BECN1 | 176 | Annotation score: | ||
K7EMA2 | K7EMA2_HUMAN | Beclin-1 | BECN1 | 106 | Annotation score: | ||
K7ERY0 | K7ERY0_HUMAN | Beclin-1 | BECN1 | 72 | Annotation score: | ||
K7EQQ7 | K7EQQ7_HUMAN | Beclin-1 | BECN1 | 59 | Annotation score: | ||
A0A087WVZ2 | A0A087WVZ2_HUMAN | Beclin-1 | BECN1 | 20 | Annotation score: | ||
K7EL88 | K7EL88_HUMAN | Beclin-1 | BECN1 | 55 | Annotation score: | ||
There is more potential isoformShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016889 Genomic DNA No translation available. KF511232 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000591085.1; ENSP00000465658.1; ENSG00000126581.13 |
UCSCi | uc060fog.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016889 Genomic DNA No translation available. KF511232 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | K7EKK2 |
PRIDEi | K7EKK2 |
Genome annotation databases
Ensembli | ENST00000591085.1; ENSP00000465658.1; ENSG00000126581.13 |
UCSCi | uc060fog.1, human |
Organism-specific databases
HGNCi | HGNC:1034, BECN1 |
OpenTargetsi | ENSG00000126581 |
VEuPathDBi | HostDB:ENSG00000126581 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000008164 |
HOGENOMi | CLU_2653822_0_0_1 |
Miscellaneous databases
ChiTaRSi | BECN1, human |
Gene expression databases
Bgeei | ENSG00000126581, Expressed in frontal cortex and 243 other tissues |
ExpressionAtlasi | K7EKK2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR007243, Atg6/Beclin IPR032913, BECN1 |
PANTHERi | PTHR12768, PTHR12768, 1 hit PTHR12768:SF6, PTHR12768:SF6, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | K7EKK2_HUMAN | |
Accessioni | K7EKK2Primary (citable) accession number: K7EKK2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2013 |
Last sequence update: | January 9, 2013 | |
Last modified: | May 25, 2022 | |
This is version 46 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |