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Protein
Submitted name:

Nuclear factor 1 X-type

Gene

NFIX

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor 1 X-typeImported
Gene namesi
Name:NFIXImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000008441.16
HGNCiHGNC:7788 NFIX

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000008441

PTM / Processingi

Proteomic databases

MaxQBiK7EKH0
PeptideAtlasiK7EKH0
PRIDEiK7EKH0

Expressioni

Gene expression databases

BgeeiENSG00000008441 Expressed in 206 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiK7EKH0 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 128CTF/NF-IInterPro annotationAdd BLAST128

Phylogenomic databases

eggNOGiKOG3663 Eukaryota
ENOG410Y16G LUCA
GeneTreeiENSGT00390000009905

Family and domain databases

InterProiView protein in InterPro
IPR000647 CTF/NFI
IPR020604 CTF/NFI_DNA-bd-dom
IPR003619 MAD_homology1_Dwarfin-type
PANTHERiPTHR11492 PTHR11492, 1 hit
PfamiView protein in Pfam
PF03165 MH1, 1 hit
SMARTiView protein in SMART
SM00523 DWA, 1 hit
PROSITEiView protein in PROSITE
PS51080 CTF_NFI_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

K7EKH0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKDEERAVK DELLGEKPEI KQKWASRLLA KLRKDIRPEF REDFVLTITG
60 70 80 90 100
KKPPCCVLSN PDQKGKIRRI DCLRQADKVW RLDLVMVILF KGIPLESTDG
110 120
ERLYKSPQCS NPGLCVQPHH IGVTIKEL
Length:128
Mass (Da):14,721
Last modified:January 9, 2013 - v1
Checksum:iB5DDD074408840F5
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q14938NFIX_HUMAN
Nuclear factor 1 X-type
NFIX
502Annotation score:
C9JWJ8C9JWJ8_HUMAN
Nuclear factor 1
NFIX
403Annotation score:
K7EN08K7EN08_HUMAN
Nuclear factor 1
NFIX
455Annotation score:
K7EJB0K7EJB0_HUMAN
Nuclear factor 1 X-type
NFIX
183Annotation score:
K7ESG9K7ESG9_HUMAN
Nuclear factor 1 X-type
NFIX
125Annotation score:
K7EMQ5K7EMQ5_HUMAN
Nuclear factor 1 X-type
NFIX
101Annotation score:
K7EPU2K7EPU2_HUMAN
Nuclear factor 1 X-type
NFIX
59Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei128Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007787 Genomic DNA No translation available.
AC022152 Genomic DNA No translation available.
AC138474 Genomic DNA No translation available.
KF456509 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000590027; ENSP00000465616; ENSG00000008441
UCSCiuc060ugj.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007787 Genomic DNA No translation available.
AC022152 Genomic DNA No translation available.
AC138474 Genomic DNA No translation available.
KF456509 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiK7EKH0
PeptideAtlasiK7EKH0
PRIDEiK7EKH0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000590027; ENSP00000465616; ENSG00000008441
UCSCiuc060ugj.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000008441.16
HGNCiHGNC:7788 NFIX
OpenTargetsiENSG00000008441
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3663 Eukaryota
ENOG410Y16G LUCA
GeneTreeiENSGT00390000009905

Miscellaneous databases

ChiTaRSiNFIX human

Gene expression databases

BgeeiENSG00000008441 Expressed in 206 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiK7EKH0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000647 CTF/NFI
IPR020604 CTF/NFI_DNA-bd-dom
IPR003619 MAD_homology1_Dwarfin-type
PANTHERiPTHR11492 PTHR11492, 1 hit
PfamiView protein in Pfam
PF03165 MH1, 1 hit
SMARTiView protein in SMART
SM00523 DWA, 1 hit
PROSITEiView protein in PROSITE
PS51080 CTF_NFI_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EKH0_HUMAN
AccessioniPrimary (citable) accession number: K7EKH0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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