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UniProtKB - K7EKD1 (K7EKD1_HUMAN)
Protein
Submitted name:
Glial fibrillary acidic protein
Gene
GFAP
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Glial fibrillary acidic proteinImported |
Gene namesi | Name:GFAPImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4235, GFAP |
VEuPathDBi | HostDB:ENSG00000131095 |
Subcellular locationi
Cytoskeleton
- intermediate filament Source: UniProtKB-KW
Keywords - Cellular componenti
Intermediate filamentARBA annotationExpressioni
Gene expression databases
Bgeei | ENSG00000131095, Expressed in dorsal motor nucleus of vagus nerve and 154 other tissues |
ExpressionAtlasi | K7EKD1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 57 | IF rodInterPro annotationAdd BLAST | 57 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 31 – 57 | Sequence analysisAdd BLAST | 27 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000159539 |
HOGENOMi | CLU_3001675_0_0_1 |
OMAi | QFLRKIH |
Family and domain databases
InterProi | View protein in InterPro IPR027701, GFAP IPR039008, IF_rod_dom |
PANTHERi | PTHR45652:SF9, PTHR45652:SF9, 1 hit |
Pfami | View protein in Pfam PF00038, Filament, 1 hit |
PROSITEi | View protein in PROSITE PS51842, IF_ROD_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All
K7EKD1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSNMHEAE EWYRSKFADL TDAAARNAEL LRQAKHEAND YRRQLQSLTC
DLESLRG
Computationally mapped potential isoform sequencesi
There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP14136 | GFAP_HUMAN | Glial fibrillary acidic protein | GFAP | 432 | Annotation score: | ||
A0A1W2PR46 | A0A1W2PR46_HUMAN | Glial fibrillary acidic protein | GFAP | 505 | Annotation score: | ||
A0A1X7SBR3 | A0A1X7SBR3_HUMAN | Glial fibrillary acidic protein | GFAP | 472 | Annotation score: | ||
K7EJU1 | K7EJU1_HUMAN | Glial fibrillary acidic protein | GFAP | 248 | Annotation score: | ||
A0A1X7SCE1 | A0A1X7SCE1_HUMAN | Glial fibrillary acidic protein | GFAP | 334 | Annotation score: | ||
A0A1W2PRT3 | A0A1W2PRT3_HUMAN | Glial fibrillary acidic protein | GFAP | 326 | Annotation score: | ||
K7EPI4 | K7EPI4_HUMAN | Glial fibrillary acidic protein | GFAP | 124 | Annotation score: | ||
A0A1W2PPA3 | A0A1W2PPA3_HUMAN | Glial fibrillary acidic protein | GFAP | 69 | Annotation score: | ||
K7EKH9 | K7EKH9_HUMAN | Glial fibrillary acidic protein | GFAP | 261 | Annotation score: | ||
K7ELP4 | K7ELP4_HUMAN | Glial fibrillary acidic protein | GFAP | 189 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 57 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015936 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000588957; ENSP00000465565; ENSG00000131095 |
UCSCi | uc060gdv.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015936 Genomic DNA No translation available. |
3D structure databases
SMRi | K7EKD1 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | K7EKD1 |
PRIDEi | K7EKD1 |
Protocols and materials databases
Antibodypediai | 3505, 3004 antibodies from 60 providers |
Genome annotation databases
Ensembli | ENST00000588957; ENSP00000465565; ENSG00000131095 |
UCSCi | uc060gdv.1, human |
Organism-specific databases
HGNCi | HGNC:4235, GFAP |
OpenTargetsi | ENSG00000131095 |
VEuPathDBi | HostDB:ENSG00000131095 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159539 |
HOGENOMi | CLU_3001675_0_0_1 |
OMAi | QFLRKIH |
Miscellaneous databases
ChiTaRSi | GFAP, human |
Gene expression databases
Bgeei | ENSG00000131095, Expressed in dorsal motor nucleus of vagus nerve and 154 other tissues |
ExpressionAtlasi | K7EKD1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR027701, GFAP IPR039008, IF_rod_dom |
PANTHERi | PTHR45652:SF9, PTHR45652:SF9, 1 hit |
Pfami | View protein in Pfam PF00038, Filament, 1 hit |
PROSITEi | View protein in PROSITE PS51842, IF_ROD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | K7EKD1_HUMAN | |
Accessioni | K7EKD1Primary (citable) accession number: K7EKD1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2013 |
Last sequence update: | January 9, 2013 | |
Last modified: | January 19, 2022 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |