UniProtKB - K7EJY8 (K7EJY8_HUMAN)
Protein
Submitted name:
Galectin-3-binding protein
Gene
LGALS3BP
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- scavenger receptor activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Galectin-3-binding proteinImported |
Gene namesi | Name:LGALS3BPImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000108679.12 |
HGNCi | HGNC:6564, LGALS3BP |
Subcellular locationi
Other locations
- membrane Source: InterPro
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5003900771 | 19 – 144 | Sequence analysisAdd BLAST | 126 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 29 ↔ 39 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondPROSITE-ProRule annotationARBA annotationProteomic databases
PeptideAtlasi | K7EJY8 |
PRIDEi | K7EJY8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000108679, Expressed in heart left ventricle and 234 other tissues |
ExpressionAtlasi | K7EJY8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 18 – 60 | SRCRInterPro annotationAdd BLAST | 43 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000162516 |
Family and domain databases
Gene3Di | 3.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF00530, SRCR, 1 hit |
PRINTSi | PR00258, SPERACTRCPTR |
SMARTi | View protein in SMART SM00202, SR, 1 hit |
SUPFAMi | SSF56487, SSF56487, 1 hit |
PROSITEi | View protein in PROSITE PS50287, SRCR_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All
K7EJY8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTPPRLFWVW LLVAGTQGSG PIMLDEVQCT GTEASLADCK SLGWLKSNCR
60 70 80 90 100
HERDAGVVCT NETRSTHTLD LSRELSEALG QIFDSQRGCD LSISVNVQGE
110 120 130 140
DALGFCGHTV ILTANLEAQA LWKEPGSNVT MSVDAECVPM VRDL
Computationally mapped potential isoform sequencesi
There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ08380 | LG3BP_HUMAN | Galectin-3-binding protein | LGALS3BP M2BP | 585 | Annotation score: | ||
K7EP36 | K7EP36_HUMAN | Galectin-3-binding protein | LGALS3BP | 259 | Annotation score: | ||
K7EJD3 | K7EJD3_HUMAN | Galectin-3-binding protein | LGALS3BP | 205 | Annotation score: | ||
K7ESM3 | K7ESM3_HUMAN | Galectin-3-binding protein | LGALS3BP | 209 | Annotation score: | ||
K7EKQ5 | K7EKQ5_HUMAN | Galectin-3-binding protein | LGALS3BP | 210 | Annotation score: | ||
K7ES75 | K7ES75_HUMAN | Galectin-3-binding protein | LGALS3BP | 88 | Annotation score: | ||
K7EN99 | K7EN99_HUMAN | Galectin-3-binding protein | LGALS3BP | 113 | Annotation score: | ||
K7ERZ6 | K7ERZ6_HUMAN | Galectin-3-binding protein | LGALS3BP | 131 | Annotation score: | ||
K7EQT9 | K7EQT9_HUMAN | Galectin-3-binding protein | LGALS3BP | 48 | Annotation score: | ||
K7ER67 | K7ER67_HUMAN | Galectin-3-binding protein | LGALS3BP | 41 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 144 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC100788 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000589906; ENSP00000465380; ENSG00000108679 |
UCSCi | uc060kxo.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC100788 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | K7EJY8 |
PRIDEi | K7EJY8 |
Protocols and materials databases
Antibodypediai | 604, 392 antibodies |
Genome annotation databases
Ensembli | ENST00000589906; ENSP00000465380; ENSG00000108679 |
UCSCi | uc060kxo.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000108679.12 |
HGNCi | HGNC:6564, LGALS3BP |
OpenTargetsi | ENSG00000108679 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000162516 |
Miscellaneous databases
ChiTaRSi | LGALS3BP, human |
Gene expression databases
Bgeei | ENSG00000108679, Expressed in heart left ventricle and 234 other tissues |
ExpressionAtlasi | K7EJY8, baseline and differential |
Family and domain databases
Gene3Di | 3.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF00530, SRCR, 1 hit |
PRINTSi | PR00258, SPERACTRCPTR |
SMARTi | View protein in SMART SM00202, SR, 1 hit |
SUPFAMi | SSF56487, SSF56487, 1 hit |
PROSITEi | View protein in PROSITE PS50287, SRCR_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | K7EJY8_HUMAN | |
Accessioni | K7EJY8Primary (citable) accession number: K7EJY8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2013 |
Last sequence update: | January 9, 2013 | |
Last modified: | August 12, 2020 | |
This is version 47 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |