UniProtKB - K7EJ90 (K7EJ90_HUMAN)
Protein
Submitted name:
NACHT, LRR and PYD domains-containing protein 2
Gene
NLRP2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: NACHT, LRR and PYD domains-containing protein 2Imported |
Gene namesi | Name:NLRP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:22948, NLRP2 |
VEuPathDBi | HostDB:ENSG00000022556.15 |
Expressioni
Gene expression databases
Bgeei | ENSG00000022556, Expressed in secondary oocyte and 167 other tissues |
ExpressionAtlasi | K7EJ90, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 94 | PyrinInterPro annotationAdd BLAST | 94 |
Phylogenomic databases
GeneTreei | ENSGT00940000161714 |
Family and domain databases
InterProi | View protein in InterPro IPR004020, DAPIN IPR011029, DEATH-like_dom_sf |
Pfami | View protein in Pfam PF02758, PYRIN, 1 hit |
SMARTi | View protein in SMART SM01289, PYRIN, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50824, DAPIN, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
K7EJ90-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVSSAQMGFN LQALLEQLSQ DELSKFKYLI TTFSLAHELQ KIPHKEVDKA
60 70 80 90 100
DGKQLVEILT THCDSYWVEM ASLQVFEKMH RMDLSERAKD EVREAALKSF
110 120
NKRKPLSLGI TRKERPPLDV DEML
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NX02 | NALP2_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 NALP2, NBS1, PAN1, PYPAF2 | 1,062 | Annotation score: | ||
J3KN39 | J3KN39_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 1,059 | Annotation score: | ||
K7EMK2 | K7EMK2_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 197 | Annotation score: | ||
A0A0G2JLX3 | A0A0G2JLX3_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 1,040 | Annotation score: | ||
A0A0G2JMG8 | A0A0G2JMG8_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 1,039 | Annotation score: | ||
A0A0G2JPQ2 | A0A0G2JPQ2_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 1,062 | Annotation score: | ||
F5H5B1 | F5H5B1_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 154 | Annotation score: | ||
F5GYZ4 | F5GYZ4_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 165 | Annotation score: | ||
F5H7Q5 | F5H7Q5_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 109 | Annotation score: | ||
K7ELX1 | K7ELX1_HUMAN | NACHT, LRR and PYD domains-containi... | NLRP2 | 140 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 124 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011476 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000588107; ENSP00000465069; ENSG00000022556 ENST00000615586; ENSP00000482327; ENSG00000273992 |
UCSCi | uc061cue.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011476 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 19479, 301 antibodies |
Genome annotation databases
Ensembli | ENST00000588107; ENSP00000465069; ENSG00000022556 ENST00000615586; ENSP00000482327; ENSG00000273992 |
UCSCi | uc061cue.1, human |
Organism-specific databases
HGNCi | HGNC:22948, NLRP2 |
OpenTargetsi | ENSG00000022556 |
VEuPathDBi | HostDB:ENSG00000022556.15 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161714 |
Miscellaneous databases
ChiTaRSi | NLRP2, human |
Gene expression databases
Bgeei | ENSG00000022556, Expressed in secondary oocyte and 167 other tissues |
ExpressionAtlasi | K7EJ90, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR004020, DAPIN IPR011029, DEATH-like_dom_sf |
Pfami | View protein in Pfam PF02758, PYRIN, 1 hit |
SMARTi | View protein in SMART SM01289, PYRIN, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50824, DAPIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | K7EJ90_HUMAN | |
Accessioni | K7EJ90Primary (citable) accession number: K7EJ90 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2013 |
Last sequence update: | January 9, 2013 | |
Last modified: | February 10, 2021 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |