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Protein
Submitted name:

Protein Hook homolog 2

Gene

HOOK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Hook homolog 2Imported
Gene namesi
Name:HOOK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000095066.11
HGNCiHGNC:19885 HOOK2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000095066

PTM / Processingi

Proteomic databases

EPDiK7EJ65
PeptideAtlasiK7EJ65
PRIDEiK7EJ65

Expressioni

Gene expression databases

BgeeiENSG00000095066 Expressed in 179 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiK7EJ65 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EJ65
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 158Calponin-homology (CH)InterPro annotationAdd BLAST153

Phylogenomic databases

GeneTreeiENSGT00690000101702

Family and domain databases

Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR008636 Hook-like_fam
PfamiView protein in Pfam
PF05622 HOOK, 2 hits
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

K7EJ65-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVDKAELCG SLLTWLQTFH VPSPCASPQD LSSGLAVAYV LNQIDPSWFN
60 70 80 90 100
EAWLQGISED PGPNWKLKVT SGLLIRGQTG EEMTRDGPAR HMSWVMGRKR
110 120 130 140 150
DRCLVSNLKM VLRSLVEYSQ DVLAHPVSEE HLPDVSLIGE FSDPAELGKL
160 170 180 190 200
LQLVLGCAIS CEKKQDHIQR IMTLEESVQH VVMEAIQELM TKDTPDSLSP

ETYGNFDSQ
Length:209
Mass (Da):23,279
Last modified:January 9, 2013 - v1
Checksum:iEBE87AB77336BC65
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96ED9HOOK2_HUMAN
Protein Hook homolog 2
HOOK2
719Annotation score:
K7EJ48K7EJ48_HUMAN
Protein Hook homolog 2
HOOK2
226Annotation score:
K7EMR5K7EMR5_HUMAN
Protein Hook homolog 2
HOOK2
157Annotation score:
K7ENU5K7ENU5_HUMAN
Protein Hook homolog 2
HOOK2
270Annotation score:
K7EMG7K7EMG7_HUMAN
Protein Hook homolog 2
HOOK2
127Annotation score:
K7EK29K7EK29_HUMAN
Protein Hook homolog 2
HOOK2
93Annotation score:
K7EJA7K7EJA7_HUMAN
Protein Hook homolog 2
HOOK2
71Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei209Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018761 Genomic DNA No translation available.
AC020934 Genomic DNA No translation available.
KF456503 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000587178; ENSP00000465042; ENSG00000095066
UCSCiuc060ude.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018761 Genomic DNA No translation available.
AC020934 Genomic DNA No translation available.
KF456503 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EJ65
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiK7EJ65
PeptideAtlasiK7EJ65
PRIDEiK7EJ65

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000587178; ENSP00000465042; ENSG00000095066
UCSCiuc060ude.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000095066.11
HGNCiHGNC:19885 HOOK2
OpenTargetsiENSG00000095066
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00690000101702

Miscellaneous databases

ChiTaRSiHOOK2 human

Gene expression databases

BgeeiENSG00000095066 Expressed in 179 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiK7EJ65 baseline and differential

Family and domain databases

Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR008636 Hook-like_fam
PfamiView protein in Pfam
PF05622 HOOK, 2 hits
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EJ65_HUMAN
AccessioniPrimary (citable) accession number: K7EJ65
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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