Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Phospholipid-transporting ATPase IK

Gene

ATP8B3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Phospholipid-transporting ATPase IKImported
Gene namesi
Name:ATP8B3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000130270.16
HGNCiHGNC:13535 ATP8B3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei157 – 174HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130270

PTM / Processingi

Proteomic databases

PRIDEiK7EJ52

Expressioni

Gene expression databases

BgeeiENSG00000130270 Expressed in 96 organ(s), highest expression level in right testis
ExpressionAtlasiK7EJ52 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EJ52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 184PhoLip_ATPase_NInterPro annotationAdd BLAST76

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410ITKD Eukaryota
ENOG410XPYK LUCA
GeneTreeiENSGT00910000144008

Family and domain databases

InterProiView protein in InterPro
IPR030349 ATP8B3
IPR023298 ATPase_P-typ_TM_dom_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
PANTHERiPTHR24092 PTHR24092, 1 hit
PTHR24092:SF78 PTHR24092:SF78, 1 hit
PfamiView protein in Pfam
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF81665 SSF81665, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

K7EJ52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTGPAQTPR STRAGPEPSP APPGPGDTGD SDVTQEGSGP AGIRGGETVI
60 70 80 90 100
RAGMGDSPGR GAPERRHKAQ PGRARKYEWR PEGPTSMGSL GQREDLQDED
110 120 130 140 150
RNSAFTWKVQ ANNRAYNGQF KEKVILCWQR KKYKTNVIRT AKYNFYSFLP
160 170 180 190 200
LNLYEQFHRV SNLFFLIIII LQSIPDISTL PWFSLSTPMV CLLFIRATRD

LVDDM
Length:205
Mass (Da):22,888
Last modified:February 19, 2014 - v2
Checksum:i3E214C7716717F92
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O60423AT8B3_HUMAN
Phospholipid-transporting ATPase IK
ATP8B3 ATP1K, FOS37502_2
1,300Annotation score:
F5H3R9F5H3R9_HUMAN
Phospholipid-transporting ATPase IK
ATP8B3
562Annotation score:
F5GZM8F5GZM8_HUMAN
Phospholipid-transporting ATPase IK
ATP8B3
86Annotation score:
H0YFS1H0YFS1_HUMAN
Phospholipid-transporting ATPase IK
ATP8B3
38Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei205Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004755 Genomic DNA No translation available.
AC012615 Genomic DNA No translation available.
KF456466 Genomic DNA No translation available.
KF459576 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000587160; ENSP00000465027; ENSG00000130270
UCSCiuc060rey.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004755 Genomic DNA No translation available.
AC012615 Genomic DNA No translation available.
KF456466 Genomic DNA No translation available.
KF459576 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EJ52
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiK7EJ52

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000587160; ENSP00000465027; ENSG00000130270
UCSCiuc060rey.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000130270.16
HGNCiHGNC:13535 ATP8B3
OpenTargetsiENSG00000130270
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITKD Eukaryota
ENOG410XPYK LUCA
GeneTreeiENSGT00910000144008

Miscellaneous databases

ChiTaRSiATP8B3 human

Gene expression databases

BgeeiENSG00000130270 Expressed in 96 organ(s), highest expression level in right testis
ExpressionAtlasiK7EJ52 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR030349 ATP8B3
IPR023298 ATPase_P-typ_TM_dom_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
PANTHERiPTHR24092 PTHR24092, 1 hit
PTHR24092:SF78 PTHR24092:SF78, 1 hit
PfamiView protein in Pfam
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF81665 SSF81665, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EJ52_HUMAN
AccessioniPrimary (citable) accession number: K7EJ52
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: February 19, 2014
Last modified: September 12, 2018
This is version 40 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again