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Protein
Submitted name:

AP-2 complex subunit beta

Gene

AP2B1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processProtein transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
AP-2 complex subunit betaImported
Gene namesi
Name:AP2B1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000006125.16
HGNCiHGNC:563 AP2B1

Subcellular locationi

Keywords - Cellular componenti

MembraneSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000006125

PTM / Processingi

Proteomic databases

EPDiK7EJ01
MaxQBiK7EJ01
PeptideAtlasiK7EJ01
PRIDEiK7EJ01

Expressioni

Gene expression databases

BgeeiENSG00000006125 Expressed in 228 organ(s), highest expression level in testis
ExpressionAtlasiK7EJ01 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliK7EJ01
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 161Adaptin_NInterPro annotationAdd BLAST160

Phylogenomic databases

eggNOGiKOG1061 Eukaryota
COG5096 LUCA
GeneTreeiENSGT00530000063138

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR026739 AP_beta
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
PANTHERiPTHR11134 PTHR11134, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

K7EJ01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SEVLAELKEY ATEVDVDFVR KAVRAIGRCA IKVEQSAERC VSTLLDLIQT
60 70 80 90 100
KVNYVVQEAI VVIRDIFRKY PNKYESIIAT LCENLDSLDE PDARAAMIWI
110 120 130 140 150
VGEYAERIDN ADELLESFLE GFHDESTQVQ LTLLTAIVKL FLKKPSETQE
160
LVQQVLSLAT QLKK
Length:164
Mass (Da):18,606
Last modified:January 9, 2013 - v1
Checksum:i8C27D8F2DC0F8201
GO

Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P63010AP2B1_HUMAN
AP-2 complex subunit beta
AP2B1 ADTB2, CLAPB1
937Annotation score:
A0A087X253A0A087X253_HUMAN
AP complex subunit beta
AP2B1
913Annotation score:
A0A087WZQ6A0A087WZQ6_HUMAN
AP-2 complex subunit beta
AP2B1
677Annotation score:
A0A087WYD1A0A087WYD1_HUMAN
AP-2 complex subunit beta
AP2B1
639Annotation score:
A0A087WU93A0A087WU93_HUMAN
AP-2 complex subunit beta
AP2B1
663Annotation score:
K7EN71K7EN71_HUMAN
AP-2 complex subunit beta
AP2B1
132Annotation score:
K7EJX1K7EJX1_HUMAN
AP-2 complex subunit beta
AP2B1
80Annotation score:
K7ERB2K7ERB2_HUMAN
AP-2 complex subunit beta
AP2B1
151Annotation score:
K7EMN7K7EMN7_HUMAN
AP-2 complex subunit beta
AP2B1
181Annotation score:
A0A087WXS3A0A087WXS3_HUMAN
AP-2 complex subunit beta
AP2B1
49Annotation score:
There is more potential isoformShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004134 Genomic DNA No translation available.
AC006237 Genomic DNA No translation available.
AC015911 Genomic DNA No translation available.
KF456264 Genomic DNA No translation available.
KF456265 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000588116; ENSP00000464966; ENSG00000006125
UCSCiuc060eda.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004134 Genomic DNA No translation available.
AC006237 Genomic DNA No translation available.
AC015911 Genomic DNA No translation available.
KF456264 Genomic DNA No translation available.
KF456265 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliK7EJ01
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiK7EJ01
MaxQBiK7EJ01
PeptideAtlasiK7EJ01
PRIDEiK7EJ01

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000588116; ENSP00000464966; ENSG00000006125
UCSCiuc060eda.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000006125.16
HGNCiHGNC:563 AP2B1
OpenTargetsiENSG00000006125
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1061 Eukaryota
COG5096 LUCA
GeneTreeiENSGT00530000063138

Miscellaneous databases

ChiTaRSiAP2B1 human

Gene expression databases

BgeeiENSG00000006125 Expressed in 228 organ(s), highest expression level in testis
ExpressionAtlasiK7EJ01 baseline and differential

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR026739 AP_beta
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
PANTHERiPTHR11134 PTHR11134, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7EJ01_HUMAN
AccessioniPrimary (citable) accession number: K7EJ01
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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