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Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei284 – 309HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiK7DVA1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini187 – 275Ig-likeInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Fragment.

K7DVA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
WACSHSMRYF YTAVSRPGRG EPRFIAVGYV DDTQFVQFDS DAASPRGEPR
60 70 80 90 100
APWVEQEGPE YWDRETQKYK RQAQTDRVSL RNLRGYYNQS EAGSHTLQRM
110 120 130 140 150
YGCDLGPDGR LLRGYNQFAY DGKDYIALNE DLRSWTAADT AAQITQRKWE
160 170 180 190 200
AARTAEQLRA YLEGTCVEWL RRYPENGKKT LQRAEHPKTH VTHHPVSDHE
210 220 230 240 250
ATLRCWALGF YPAEITLTWQ RDGEDQTQDT ELVETRPAGD GTFQKWAAVV
260 270 280 290 300
VPSGEEQRYT CHVQHEGLPE PLTLRWGPSS QPTIPIVGIV AGLAVLAVLA
310 320
VLGAVMAVVM CRRKSSGGKG GSYSQAASS
Length:329
Mass (Da):36,988
Last modified:January 9, 2013 - v1
Checksum:i59E5133EA1005252
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei329Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JN887337 mRNA Translation: AFH75432.1
UniGeneiHs.656020
Hs.743218

Similar proteinsi

Entry informationi

Entry nameiK7DVA1_HUMAN
AccessioniPrimary (citable) accession number: K7DVA1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: February 28, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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