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Protein

Coatomer subunit gamma

Gene

COPG2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Coatomer subunit gammaUniRule annotation
Gene namesi
Name:COPG2Imported
ORF Names:CK820_G0013807Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 7

Organism-specific databases

VGNCiVGNC:13640 COPG2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSPTRG00000022792 Expressed in 6 organ(s), highest expression level in cerebellum

Interactioni

Subunit structurei

Oligomeric complex.UniRule annotation

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000033748

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 538Adaptin_NInterPro annotationAdd BLAST514
Domaini610 – 756COP-gamma_platfInterPro annotationAdd BLAST147
Domaini758 – 870Coatomer_g_CplaInterPro annotationAdd BLAST113

Sequence similaritiesi

Belongs to the COPG family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
GeneTreeiENSGT00390000016313
KOiK17267
OrthoDBiEOG091G0HWQ

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

K7DFG0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKKFDKKDE ESGSGSNPFQ HLEKSAVLQE ARIFNETPIN PRRCLHILTK
60 70 80 90 100
ILYLLNQGEH FGTTEATEAF FAMTRLFQSN DQTLRRMCYL TIKEMATISE
110 120 130 140 150
DVIIVTSSLT KDMTGKEDVY RGPAIRALCR ITDGTMLQAI ERYMKQAIVD
160 170 180 190 200
KVSSVSSSAL VSSLHMMKIS YDVVKRWINE AQEAASSDNI MVQYHALGVL
210 220 230 240 250
YHLRKNDRLA VSKMLNKFTK SGLKSQFAYC MLIRIASRLL KETEDGHESP
260 270 280 290 300
LFDFIESCLR NKHEMVIYEA ASAIIHLPNC TARELAPAVS VLQLFCSSPK
310 320 330 340 350
PALRYAAVRT LNKVAMKHPS AVTACNLDLE NLITDSNRSI ATLAITTLLK
360 370 380 390 400
TGSESSVDRL MKQISSFVSE ISDEFKVVVV QAISALCQKY PRKHSVMMTF
410 420 430 440 450
LSNMLRDDGG FEYKRAIVDC IISIVEENPE SKEAGLAHLC EFIEDCEHTV
460 470 480 490 500
LATKILHLLG KEGPRTPVPS KYIRFIFNRV VLENEAVRAA AVSALAKFGA
510 520 530 540 550
QNESLLPSIL VLLQRCMMDT DDEVRDRATF YLNVLQQRQM ALNATYIFNG
560 570 580 590 600
LTVSVPGMEK ALHQYTLEPS EKPFDMKSIP LAMAPVFEQK AEITLVATKP
610 620 630 640 650
EKLAPSRQDI FQEQLAAIPE FLNIGPLFKS SEPVQLTEAE TEYFVRCIKH
660 670 680 690 700
MFTNHIVFQF DCTNTLNDQL LEKVTVQMEP SDSYEVLSCI PAPSLPYNQP
710 720 730 740 750
GICYTLVRLP DDDPTAVAGS FSCTMKFTVR DCDPNTGVPD EDGYDDEYVL
760 770 780 790 800
EDLEVTVSDH IQKVLKPNFA AAWEEVGDTF EKEETFALSS TKTLEEAVNN
810 820 830 840 850
IITFLGMQPC ERSDKVPENK NSHSLYLAGI FRGGYDLLVR SRLALADGVT
860 870
MQVTVRSKER TPVDVILASV G
Length:871
Mass (Da):97,622
Last modified:January 9, 2013 - v1
Checksum:iD361A0E74069CBEB
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3TN91A0A2I3TN91_PANTR
Coatomer subunit gamma
COPG2 CK820_G0013807
726Annotation score:
A0A2I3TBJ3A0A2I3TBJ3_PANTR
Coatomer subunit gamma
729Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC187610 Genomic DNA No translation available.
AC216085 Genomic DNA No translation available.
GABC01005235 mRNA Translation: JAA06103.1
GABE01004970 mRNA Translation: JAA39769.1
NBAG03000017 Genomic DNA Translation: PNI99538.1
RefSeqiXP_519383.3, XM_519383.6

Genome annotation databases

EnsembliENSPTRT00000036502; ENSPTRP00000033748; ENSPTRG00000022792
GeneIDi463730
KEGGiptr:463730

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC187610 Genomic DNA No translation available.
AC216085 Genomic DNA No translation available.
GABC01005235 mRNA Translation: JAA06103.1
GABE01004970 mRNA Translation: JAA39769.1
NBAG03000017 Genomic DNA Translation: PNI99538.1
RefSeqiXP_519383.3, XM_519383.6

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000033748

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000036502; ENSPTRP00000033748; ENSPTRG00000022792
GeneIDi463730
KEGGiptr:463730

Organism-specific databases

CTDi26958
VGNCiVGNC:13640 COPG2

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
GeneTreeiENSGT00390000016313
KOiK17267
OrthoDBiEOG091G0HWQ

Gene expression databases

BgeeiENSPTRG00000022792 Expressed in 6 organ(s), highest expression level in cerebellum

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiK7DFG0_PANTR
AccessioniPrimary (citable) accession number: K7DFG0
Secondary accession number(s): A0A2J8QTD3, H2QVE1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2013
Last sequence update: January 9, 2013
Last modified: November 7, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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